Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Ana M. Aransay"'
Autor:
Neda Kathami, Carolina Moreno-Vicente, Pablo Martín, Jhonatan A. Vergara-Arce, Raquel Ruiz-Hernández, Daniela Gerovska, Ana M. Aransay, Marcos J. Araúzo-Bravo, Sandra Camarero-Espinosa, Ander Abarrategi
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Recombinant human bone morphogenetic protein 2 (rhBMP-2) and human bone marrow mesenchymal stromal cells (hBM-MSCs) have been thoroughly studied for research and translational bone regeneration purposes. rhBMP-2 induces bone forma
Externí odkaz:
https://doaj.org/article/21c10d54bce543f89cca0a7db72fcc07
Autor:
Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana García-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asís Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113924- (2024)
Summary: The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R (HuR), a hub in liver cancer. Here, we show that HuR is
Externí odkaz:
https://doaj.org/article/ac05448b67bf43d08eefd6737eb5e995
Autor:
Ainize Peña-Cearra, Deguang Song, Janire Castelo, Ainhoa Palacios, Jose Luis Lavín, Mikel Azkargorta, Felix Elortza, Miguel Fuertes, Miguel Angel Pascual-Itoiz, Diego Barriales, Itziar Martín-Ruiz, Asier Fullaondo, Ana M. Aransay, Hector Rodríguez, Noah W. Palm, Juan Anguita, Leticia Abecia
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Recent evidence demonstrates potential links between mitochondrial dysfunction and inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the intestinal microbiota and host mitochondria may modulate intestinal inf
Externí odkaz:
https://doaj.org/article/3dff9ee3e3a641b592f1a6aa0abdf433
Autor:
Raquel García-Vílchez, Ana M. Añazco-Guenkova, Sabine Dietmann, Judith López, Virginia Morón-Calvente, Silvia D’Ambrosi, Paz Nombela, Kepa Zamacola, Isabel Mendizabal, Saioa García-Longarte, Amaia Zabala-Letona, Ianire Astobiza, Sonia Fernández, Alejandro Paniagua, Borja Miguel-López, Virginie Marchand, Diego Alonso-López, Angelika Merkel, Ignacio García-Tuñón, Aitziber Ugalde-Olano, Ana Loizaga-Iriarte, Isabel Lacasa-Viscasillas, Miguel Unda, Mikel Azkargorta, Félix Elortza, Laura Bárcena, Monika Gonzalez-Lopez, Ana M. Aransay, Tomás Di Domenico, Manuel A. Sánchez-Martín, Javier De Las Rivas, Sònia Guil, Yuri Motorin, Mark Helm, Pier Paolo Pandolfi, Arkaitz Carracedo, Sandra Blanco
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-36 (2023)
Abstract Newly growing evidence highlights the essential role that epitranscriptomic marks play in the development of many cancers; however, little is known about the role and implications of altered epitranscriptome deposition in prostate cancer. He
Externí odkaz:
https://doaj.org/article/23776f080b2242829817059af1fa8867
Autor:
Silvia D’Ambrosi, Raquel García-Vílchez, Darek Kedra, Patrice Vitali, Nuria Macias-Cámara, Laura Bárcena, Monika Gonzalez-Lopez, Ana M. Aransay, Sabine Dietmann, Antonio Hurtado, Sandra Blanco
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-18 (2024)
ABSTRACTRNA modifications, including N-7-methylguanosine (m7G), are pivotal in governing RNA stability and gene expression regulation. The accurate detection of internal m7G modifications is of paramount significance, given recent associations betwee
Externí odkaz:
https://doaj.org/article/0c1d37e430854e06bcbba4378800058e
Autor:
Ana García-del Río, Endika Prieto-Fernández, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Borja Jimenez-Lasheras, So Young Lee, Adrián Barreira-Manrique, Samanta Romina Zanetti, Ander de Blas, Paloma Velasco-Beltrán, Alexandre Bosch, Ana M. Aransay, Asis Palazon
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Factor-inhibiting HIF (FIH) is an asparagine hydroxylase that acts on hypoxia-inducible factors (HIFs) to control cellular adaptation to hypoxia. FIH is expressed in several tumor types, but its impact in tumor progression remains largely unexplored.
Externí odkaz:
https://doaj.org/article/cb78c3a835404ee1b3efceb52718347e
Autor:
Montse Baldan-Martin, Cristina Rubín de Célix, Macarena Orejudo, Lorena Ortega Moreno, Samuel Fernández-Tomé, Irene Soleto, Cristina Ramirez, Ricardo Arroyo, Paloma Fernández, Cecilio Santander, José Andrés Moreno-Monteagudo, María José Casanova, Fernando Casals, Sergio Casabona, Irene Becerro, Juan J. Lozano, Ana M. Aransay, María Chaparro, Javier P. Gisbert
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15691 (2023)
Biological therapies only benefit one-third of patients with Crohn’s disease (CD). For this reason, a deeper understanding of the mechanisms by which biologics elicit their effect on intestinal mucosa is needed. Increasing evidence points toward th
Externí odkaz:
https://doaj.org/article/f83f7d7f18df4b6a859293ce39bab831
Autor:
Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Several proteomic approaches allow the analysis of covalent protein SUMOylation, but it remains challenging to systematically study the consequences of a substrate being modified. Here, the authors combine proximity biotinylation and protein-fragment
Externí odkaz:
https://doaj.org/article/a373110170724930bd012a7ad3fa350e
Autor:
Ainara Cano, Mercedes Vazquez-Chantada, Javier Conde-Vancells, Aintzane Gonzalez-Lahera, David Mosen-Ansorena, Francisco J. Blanco, Karine Clément, Judith Aron-Wisnewsky, Albert Tran, Philippe Gual, Carmelo García-Monzón, Joan Caballería, Azucena Castro, María Luz Martínez-Chantar, José M. Mato, Huiping Zhu, Richard H. Finnell, Ana M. Aransay
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 337 (2023)
Low serum folate levels are inversely related to metabolic associated fatty liver disease (MAFLD). The role of the folate transporter gene (SLC19A1) was assessed to clarify its involvement in lipid accumulation during the onset of MAFLD in humans and
Externí odkaz:
https://doaj.org/article/604e1f5cef3f4e0f877c63c8750f776b
Autor:
Marc Clos-Garcia, Naiara Andrés-Marin, Gorka Fernández-Eulate, Leticia Abecia, José L. Lavín, Sebastiaan van Liempd, Diana Cabrera, Félix Royo, Alejandro Valero, Nerea Errazquin, María Cristina Gómez Vega, Leila Govillard, Michael R. Tackett, Genesis Tejada, Esperanza Gónzalez, Juan Anguita, Luis Bujanda, Ana María Callejo Orcasitas, Ana M. Aransay, Olga Maíz, Adolfo López de Munain, Juan Manuel Falcón-Pérez
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 499-511 (2019)
Background: Fibromyalgia is a complex, relatively unknown disease characterised by chronic, widespread musculoskeletal pain. The gut-brain axis connects the gut microbiome with the brain through the enteric nervous system (ENS); its disruption has be
Externí odkaz:
https://doaj.org/article/743742b5d6904901a05c89b0a7d10850