Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ana M. Rossi"'
Autor:
Xiangdong Su, Wolfgang Dohle, Stephen J. Mills, Joanna M. Watt, Ana M. Rossi, Colin W. Taylor, Barry V. L. Potter
Publikováno v:
ACS Omega, Vol 5, Iss 44, Pp 28793-28811 (2020)
Externí odkaz:
https://doaj.org/article/d94ccb6b6c4f468785da8db2c6a81162
Autor:
Ana M. Rossi, Andrew M. Riley, Geneviève Dupont, Taufiq Rahman, Barry V.L. Potter, Colin W. Taylor
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109932- (2021)
Summary: Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels that link extracellular stimuli to Ca2+ signals. Ca2+ release from intracellular stores is “quantal”: low IP3 concentrations rapidly release a fraction of the
Externí odkaz:
https://doaj.org/article/d8a24df4d63f46e6850a128da1909549
Publikováno v:
Cell Calcium. :102761
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b4606f64463772a48734a97838989be
https://doi.org/10.1016/j.ceca.2023.102761
https://doi.org/10.1016/j.ceca.2023.102761
Autor:
Colin W. Taylor, Barry V. L. Potter, Stephen J Mills, Xiangdong Su, Ana M. Rossi, Wolfgang Dohle, Joanna M. Watt
Publikováno v:
ACS Omega, Vol 5, Iss 44, Pp 28793-28811 (2020)
d-myo-Inositol 1,4,5-trisphosphate receptors (IP3Rs) are Ca2+ channels activated by the intracellular messenger inositol 1,4,5-trisphosphate (IP3, 1). The glyconucleotide adenophostin A (AdA, 2) is a potent agonist of IP3Rs. A recent synthesis of d-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41599b32dc386f30400b670167e80a8c
https://doaj.org/article/d94ccb6b6c4f468785da8db2c6a81162
https://doaj.org/article/d94ccb6b6c4f468785da8db2c6a81162
Autor:
Stephen J Mills, Ana M. Rossi, Daniel Bakowski, Vera Konieczny, Colin W. Taylor, Barry V. L. Potter
Publikováno v:
Journal of Medicinal Chemistry
Analogues of the Ca2+-releasing intracellular messenger d-myo-inositol 1,4,5-trisphosphate [1, Ins(1,4,5)P3] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural product mimic adenophostin 2 by d-chiro-inositol i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92890ded947a792bbeaa992d5f20b5ce
http://europepmc.org/articles/PMC7104261
http://europepmc.org/articles/PMC7104261
Autor:
Ana M. Rossi, Andrew M. Riley, Colin W. Taylor, Taufiq Rahman, Barry V. L. Potter, Geneviève Dupont
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109932-(2021)
Cell Reports
Cell Reports
Summary Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels that link extracellular stimuli to Ca2+ signals. Ca2+ release from intracellular stores is “quantal”: low IP3 concentrations rapidly release a fraction of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736722494650aa7d895e81ababb6b67b
https://ora.ox.ac.uk/objects/uuid:783f4d6d-0ebb-4780-a849-6882b4946f44
https://ora.ox.ac.uk/objects/uuid:783f4d6d-0ebb-4780-a849-6882b4946f44
Publikováno v:
Biochemical Journal
Binding of IP3 (inositol 1,4,5-trisphosphate) to the IP3-binding core (residues 224–604) of IP3Rs (IP3 receptors) initiates opening of these ubiquitous intracellular Ca2+ channels. The mechanisms are unresolved, but require conformational changes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0312b59c3c22173611e3ca00a9de370
Work-related stress jeopardizes the organizational member’s health, with 50 to 80% of all diseases being psychosomatic or of a stress-related nature. Psychological consequences of stress have been studied at the University of Michigan Institute for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ee61d1d528cfe1d726aa96e1e42993c
https://doi.org/10.1201/9781003072430-6
https://doi.org/10.1201/9781003072430-6
Autor:
Andrew M. Riley, Megan L. Shipton, Charles A. Brearley, Colin W. Taylor, Barry V. L. Potter, Ana M. Rossi
Publikováno v:
Journal of Medicinal Chemistry
Chiral sugar derivatives are potential cyclitol surrogates of the Ca2+-mobilizing intracellular messenger d-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P3]. Six novel polyphosphorylated analogues derived from both d- and l-glucose were synthesized. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b86de8579e66044c43db0bd2da75a48
https://ueaeprints.uea.ac.uk/id/eprint/74760/
https://ueaeprints.uea.ac.uk/id/eprint/74760/
Autor:
Ana M. Rossi, Colin W. Taylor
Synthetic Ca2+ indicators are widely used to report changes in free [Ca2+], usually in the cytosol but also within organelles. Mag-Fluo-4, loaded into the endoplasmic reticulum (ER) by incubating cells with Mag-Fluo-4 AM, has been used to measure cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72e27b1e859a9637ba01cbd187d4b4f
https://www.repository.cam.ac.uk/handle/1810/302945
https://www.repository.cam.ac.uk/handle/1810/302945