Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ana M Rodríguez-Piñeiro"'
Autor:
Joakim H Bergström, Katarina A Berg, Ana M Rodríguez-Piñeiro, Bärbel Stecher, Malin E V Johansson, Gunnar C Hansson
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104186 (2014)
The MUC2 mucin is the major constituent of the two mucus layers in colon. Mice lacking the disulfide isomerase-like protein Agr2 have been shown to be more susceptible to colon inflammation. The Agr2(-/-) mice have less filled goblet cells and were n
Externí odkaz:
https://doaj.org/article/a32a76d0146a45258a5f10e12b382c2e
Autor:
Loretta De Chiara, Ana M Rodríguez-Piñeiro, Oscar J Cordero, Lidia Vázquez-Tuñas, Daniel Ayude, Francisco J Rodríguez-Berrocal, María Páez de la Cadena
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107470 (2014)
One of the main aims of the follow-up after curative resection of colorectal cancer is the early detection and treatment of tumor recurrence. We previously demonstrated decreased preoperative soluble CD26 (sCD26) levels in serum from colorectal cance
Externí odkaz:
https://doaj.org/article/4d3a42175c5249f9b4eacbc6bdb5e4b2
Autor:
Vicenta S. Martínez-Zorzano, María Páez de la Cadena, Francisco J. Rodríguez-Berrocal, Ana M. Rodríguez-Piñeiro, Andrés García-Lorenzo
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 11, Pp 14401-14420 (2012)
Colorectal cancer is still a major health burden worldwide, and its diagnosis has not improved in recent years due to a lack of appropriate diagnostic serum markers. Aiming to find new diagnostic proteins, we applied the proteomic DIGE technology to
Externí odkaz:
https://doaj.org/article/d0486e5a457544dabace40fe9605f055
Autor:
Erik Ehrencrona, Christian V. Recktenwald, Sergio Trillo-Muyo, Malin Bäckström, Pablo Gallego, Malin Johansson, Maria-Jose Garcia-Bonete, Ana M. Rodríguez-Piñeiro, Sjoerd van der Post, Gunnar C. Hansson
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
Mucus forms an important protective barrier that minimizes bacterial contact with the colonic epithelium. Intestinal mucus is organized in a complex network with several specific proteins, including the mucin-2 (MUC2) and the abundant IgGFc-binding p
Autor:
Ana M. Rodríguez-Piñeiro, Christopher M. Evans, Dalia Fakih, Anna Ermund, Sergio Trillo-Muyo, Gunnar C. Hansson
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Am J Physiol Lung Cell Mol Physiol
Am J Physiol Lung Cell Mol Physiol
The organization of the normal airway mucus system differs in small experimental animals from that in humans and large mammals. To address normal murine airway mucociliary clearance, Alcian blue-stained mucus transport was measured ex vivo on trachea
Autor:
Sonya Jackson, Christopher M. Evans, Joan Antoni Fernández-Blanco, Dalia Fakih, Dave Singh, Annika Åstrand, Gunnar C. Hansson, Liisa Arike, Christopher McCrae, Anna Ermund, Ana M. Rodríguez-Piñeiro, Elin Skansebo, Beatriz Martínez-Abad, James Root
Publikováno v:
JCI Insight
The respiratory tract is normally kept essentially free of bacteria by cilia-mediated mucus transport, but in chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), bacteria and mucus accumulates instead. To address the mechanisms beh
Publikováno v:
Gut Microbes. 6:326-330
The intestinal mucus is a pivotal part of our intestinal protection. It provides slow diffusion of protective molecules, trapping of luminal material as bacteria and smooth transport in the small intestine. In colon it restricts bacterial access to t
Autor:
Malin E. V. Johansson, André Schütte, Sjoerd van der Post, Ana M. Rodríguez-Piñeiro, Catharina Wising, Joakim H. Bergström, Jenny K. Gustafsson, Anna Ermund, Thaher Pelaseyed, Frida Svensson, Gunnar C. Hansson, George M. H. Birchenough, Elisabeth E. L. Nyström
Publikováno v:
Immunological Reviews. 260:8-20
The gastrointestinal tract is covered by mucus that has different properties in the stomach, small intestine, and colon. The large highly glycosylated gel-forming mucins MUC2 and MUC5AC are the major components of the mucus in the intestine and stoma
Autor:
Hasse Karlsson, Jessica M. Holmén Larsson, Ana M. Rodríguez-Piñeiro, Gunnar C. Hansson, Kristina A. Thomsson
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G357-G363
The mouse intestinal mucus is mainly made up by the gel-forming Muc2 mucin and the stomach surface mucus Muc5ac, both extensively O-glycosylated. The oligosaccharide diversity provides a vast library of potential recognition sites for both commensal
Autor:
Gunnar C. Hansson, André Schütte, Jenny K. Gustafsson, Anna Ermund, Joakim H. Bergström, Malin E. V. Johansson, Ana M. Rodríguez-Piñeiro
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G348-G356
The mucus that protects the surface of the gastrointestinal tract is rich in specialized O-glycoproteins called mucins, but little is known about other mucus proteins or their variability along the gastrointestinal tract. To ensure that only mucus wa