Zobrazeno 1 - 10 of 52 pro vyhledávání: '"Ana M, Bajo"'
1
Tumorigenic transformation of human prostatic epithelial cell line RWPE-1 by growth hormone-releasing hormone (GHRH)
Autor: Laura Muñoz‐Moreno, M. José Carmena, Juan C. Prieto, Andrew V. Schally, Ana M. Bajo
Publikováno v: The Prostate. 82(8)
Growth hormone-releasing hormone (GHRH) and its receptors have been implicated in the progression of various tumors. In this study, we analyzed the carcinogenetic potential of exposure to GHRH of a nontumor human prostate epithelial cell line (RWPE-1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850bf417926ca752092efb33ea8c4781
https://pubmed.ncbi.nlm.nih.gov/35322894
Zobrazit plný text záznamu
2
Water soluble, optically active monofunctional Pd(ii) and Pt(ii) compounds: promising adhesive and antimigratory effects on human prostate PC-3 cancer cells
Autor: Tomás Cuenca, Elena de la Torre-Rubio, Lourdes Gude, Laura Muñoz-Moreno, Eva Royo, Isabel de la Cueva-Alique, Ana M. Bajo
Publikováno v: Dalton Transactions. 48:14279-14293
New water soluble, enantiopure palladium and platinum compounds RN-[M{(1S,4R)-κNOH,κ2NH(2-pic)}Cl]Cl and SN-[M{(1R,4S)-κNOH,κ2NH(2-pic)}Cl]Cl (2-pic = 2-picolyl, M = Pd 1 and 1', Pt 2 and 2', respectively), and heterometallic Pd/Ti [(η5-C5H5)2Ti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b470f6253f8edb39b1e7a49013f281b5
https://doi.org/10.1039/c9dt02873k
Zobrazit plný text záznamu
3
Insight into the antitumor activity of carbosilane Cu(ii)–metallodendrimers through their interaction with biological membrane models
Autor: Rafael Gómez, Alberto Fattori, Sandra García-Gallego, Maria Francesca Ottaviani, Paula Ortega, Riccardo Carloni, Michela Cangiotti, Natalia Sanz del Olmo, F. Javier de la Mata, Ana M. Bajo
Publikováno v: Nanoscale. 11:13330-13342
Current cancer therapies present serious drawbacks including severe side-effects and development of drug resistance. Strategies based on nanosized metallodrugs combine the structural diversity and non-classical modes of action of metal complexes with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2181c985c23a953ccb71ae87aa525ea0
https://doi.org/10.1039/c9nr03313k
Zobrazit plný text záznamu
4
Growth hormone-releasing hormone induced transactivation of epidermal growth factor receptor in human triple-negative breast cancer cells
Autor: Eva Vacas, María J. Carmena, Andrew V. Schally, Ana M. Bajo, Laura Muñoz-Moreno, Pedro L. Valenzuela, Juan C. Prieto
Publikováno v: Peptides. 86:153-161
Triple-negative breast cancer (TNBC) is a subset of breast cancers which is negative for expression of estrogen and progesterone receptors and human epidermal growth factor receptor-2 (HER2). Chemotherapy is currently the only form of treatment for w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde14fa12e4ecf0572422ca0e322b8a6
https://doi.org/10.1016/j.peptides.2016.11.004
Zobrazit plný text záznamu
5
In vitro and in vivo evaluation of first-generation carbosilane arene Ru(II)-metallodendrimers in advanced prostate cancer
Autor: Laura Muñoz-Moreno, Marta Maroto-Díaz, Sandra García-Gallego, Natalia Sanz del Olmo, F. Javier de la Mata, M. José Carmena, Rafael Gómez, Ana M. Bajo
Publikováno v: e_Buah Biblioteca Digital Universidad de Alcalá
instname
Background Prostate cancer is the fifth cause of death among men worldwide. Patients suffering resistant prostate tumor, unresponsive to common treatments, can only be treated with palliative therapy. Materials and methods Ruthenium(II) carbosilane m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdc20968f39415bd299552d7b55311d
http://hdl.handle.net/10017/46748
Zobrazit plný text záznamu
6
Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer
Autor: Ana M. Bajo, Laura Muñoz-Moreno, María I. Arenas, Andrew V. Schally, Juan C. Prieto, Manuel Sánchez-Chapado, María J. Carmena
Publikováno v: Oncotarget
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Growth hormone-releasing hormone (GHRH) and its receptors have been implicated in the progression of various tumors. In vitro and in vivo studies have demonstrated that GHRH antagonists inhibit the growth of several cancers. GHRH antagonists, JMR-132
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28aee1a0430ca1e424b196853895f0c1
http://europepmc.org/articles/PMC5239544
Zobrazit plný text záznamu
7
Cyclopentadienyl ruthenium(II) carbosilane metallodendrimers as a promising treatment against advanced prostate cancer
Autor: Natalia Sanz del Olmo, Sandra García-Gallego, F. Javier de la Mata, Paula Ortega, Rafael Gómez, Maria Bryszewska, Ana M. Bajo, Maksim Ionov
Publikováno v: European Journal of Medicinal Chemistry. 199:112414
In searching for efficient and selective antitumour drugs, a new family of carbosilane metallodendrimers functionalized with [Ru(η5-C5H5)(PTA)Cl] (PTA = 1,3,5-triaza-7-phosphatricyclo-[3.3.1.1] decane) is reported. Experiments of the biophysical cha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d31e31a38e35f38cb2bfa015a9f5f78
https://doi.org/10.1016/j.ejmech.2020.112414
Zobrazit plný text záznamu
8
Growth hormone-releasing hormone receptor antagonists modify molecular machinery in the progression of prostate cancer
Autor: Andrew V. Schally, Juan C. Prieto, M. José Carmena, Ana M. Bajo, Laura Muñoz-Moreno
Publikováno v: The Prostate. 78(12)
BACKGROUND Therapeutic strategies should be designed to transform aggressive prostate cancer phenotypes to a chronic situation. To evaluate the effects of the new growth hormone-releasing hormone receptor (GHRH-R) antagonists: MIA-602, MIA-606, and M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16291dddba0981d71e233e64739851a0
https://pubmed.ncbi.nlm.nih.gov/29748961
Zobrazit plný text záznamu
9
Biological evaluation of water soluble arene Ru(II) enantiomers with amino-oxime ligands
Autor: Laura Muñoz-Moreno, Isabel de la Cueva-Alique, Tomás Cuenca, Ana M. Bajo, Eva Royo, Adrián Pérez-Redondo, Isabel Marzo, Sara Sierra, Lourdes Gude
Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
New water soluble, enantiopure arene ruthenium compound S Ru S N -(1 R ,4 S )-[(η 6 - p -cymene)Ru{ĸNH(Bn),ĸNOH}Cl]Cl (Bn = benzyl, 1a ′) has been synthesized. The novel compound along with that previously described R Ru R N -(1 S ,4 R )-[(η 6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c008e63bb5ceb36d80e370e7128a7ee1
http://zaguan.unizar.es/record/78316
Zobrazit plný text záznamu
10
Hydrogen Bonding and Anticancer Properties of Water‐Soluble Chiral p ‐Cymene Ru II Compounds with Amino‐Oxime Ligands
Autor: Laura Muñoz-Moreno, Eva Royo, Ana M. Bajo, María Contel, Yosra Benabdelouahab, Isabel de la Cueva-Alique, Tomás Cuenca, Malgorzata Frik, Mohammed Amin El Amrani
Publikováno v: European Journal of Inorganic Chemistry. 2015:2295-2307
The investigation of the hydrogen-bonding effect on the aggregation tendency of ruthenium compounds [(η6-p-cymene)Ru(κNHR,κNOH)Cl]Cl (R = Ph (1a), Bn (1b)) and [(η6-p-cymene)Ru(κ2NH(2-pic),κNOH)][PF6]2 (1c), [(η6-p-cymene)Ru(κNHBn,κNO)Cl] (2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4b73bf6c02b589a50468a0ee38edf9e
https://doi.org/10.1002/ejic.201500097
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje