Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ana Luiza Drumond-Bock"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101785- (2022)
Summary: Molecular cloning of BRD4-L is a challenging technique, because the DNA insert is formed by a long, GC-rich sequence, which folds into secondary structures. The present protocol defines a specific strategy to amplify BRD4-L, followed by the
Externí odkaz:
https://doaj.org/article/8599d499c2dd4291ad6fee99695de249
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract High-grade serous ovarian carcinoma (HGSOC) is the most aggressive type of ovarian cancer, often diagnosed at advanced stages. Molecularly, HGSOC shows high degree of genomic instability associated with large number of genetic alterations. B
Externí odkaz:
https://doaj.org/article/6c7535b1b6594f3bb5a8810ca124ef10
Autor:
Magdalena Cybula, Luyao Wang, Lin Wang, Ana Luiza Drumond-Bock, Katherine M. Moxley, Magdalena Bieniasz
Publikováno v:
Genes & Cancer
The sfRon kinase is an important therapeutic target in ovarian cancer that contributes to prominent tumor growth and disease progression. We reasoned that a multi-kinase inhibition of sfRon pathway might be an effective strategy to achieve a sustaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c9a23da557aded8de69c412eeb9ac9
http://europepmc.org/articles/PMC7805538
http://europepmc.org/articles/PMC7805538
Autor:
Ana Luiza Drumond-Bock, Luyao Wang, Lin Wang, Magdalena Cybula, Maria Rostworowska, Magdalena Bieniasz
Publikováno v:
Cancer Research. 82:LB542-LB542
High-grade serous ovarian carcinoma (HGSOC) is one of the deadliest types of cancer in the US. Occurrence of sporadic HGSOC is associated with high genomic instability, which causes amplification and deletion of several different genes. BRD4 is one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::142382b4afcda82109ffab300749a1ef
https://doi.org/10.1158/1538-7445.am2022-lb542
https://doi.org/10.1158/1538-7445.am2022-lb542
Autor:
Magdalena Cybula, Maria Rostworowska, Lin Wang, Summer Wang, Ana Luiza Drumond-Bock, Magdalena Bieniasz
Publikováno v:
Cancer Research. 82:LB125-LB125
The reprogramming of cellular metabolism is an important hallmark of cancer allowing tumor cells to survive and proliferate. Recent data revealed that subsets of ovarian cancer with invasive and metastatic phenotype are highly metabolically active wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a867e5400638ba5b389d8d7de8bf43
https://doi.org/10.1158/1538-7445.am2022-lb125
https://doi.org/10.1158/1538-7445.am2022-lb125