Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ana Lopez-Campistrous"'
Autor:
Ana Lopez-Campistrous, Esther Ekpe Adewuyi, Matthew G.K. Benesch, Yi Man Ko, Raymond Lai, Aducio Thiesen, Jay Dewald, Peng Wang, Karen Chu, Sunita Ghosh, David C. Williams, Larissa J. Vos, David N. Brindley, Todd P.W. McMullen
Publikováno v:
EBioMedicine, Vol 12, Iss C, Pp 86-97 (2016)
Dedifferentiation of follicular cells is a central event in resistance to radioactive iodine and patient mortality in papillary thyroid carcinoma (PTC). We reveal that platelet derived growth factor receptor alpha (PDGFRα) specifically drives dediff
Externí odkaz:
https://doaj.org/article/c5c4da49361e49e0a54a8697243b501a
Autor:
Xiaohua Song, Ana Lopez-Campistrous, Lucy Sun, Nancy A Dower, Noemi Kedei, Jing Yang, Jessica S Kelsey, Nancy E Lewin, Tim E Esch, Peter M Blumberg, James C Stone
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72331 (2013)
Ingenol-3-angelate (I3A) is a non-tumor promoting phorbol ester-like compound identified in the sap of Euphoria peplus. Similar to tumor promoting phorbol esters, I3A is a diacylglycerol (DAG) analogue that binds with high affinity to the C1 domains
Externí odkaz:
https://doaj.org/article/4f9d2b403168453499b6bf3f80e2e1ab
Publikováno v:
Human Pathology. 91:36-42
Summary Function of the thyroid follicular cell depends on nuclear expression of thyroid transcription factor 1 (TTF1). Regulation of this key protein regulating iodide transport is not well known, but its loss is linked to the most lethal of thyroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5a985a2fde8de6049154cb99acc890
https://doi.org/10.1016/j.humpath.2019.06.002
https://doi.org/10.1016/j.humpath.2019.06.002
Autor:
Ana Lopez-Campistrous, Hans-Soenke Jans, Jennifer Dufour, Frank Wuest, Melinda Wuest, Todd P. W. McMullen, Michael Wagner, Darryl D. Glubrecht
Publikováno v:
Endocrine-related cancer. 27(9)
Targeted therapy is increasingly used to manage metastatic papillary thyroid cancer. The focus of the present study was to examine glucose metabolism and tumor responses for thyroid cancer xenografts expressing the glycolytic pathway modulators plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0b7ab0427c5366f02e93fb1c03c0f9
https://pubmed.ncbi.nlm.nih.gov/32590338
https://pubmed.ncbi.nlm.nih.gov/32590338
Autor:
Melinda Wuest, Michael Wagner, Ana Lopez-Campistrous, Todd P. W. McMullen, Ingrit Hamann, Frank Wuest
Publikováno v:
Nuclear Medicine and Biology. 58:51-58
Introduction Receptor tyrosine kinase (RTK) platelet-derived growth factor receptor-alpha (PDGFRα) was recently identified as a molecular switch for dedifferentiation in thyroid cancer that predicts resistance to therapy as well as recurrence of dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ed82b1b9ad41bda6d8b0c46e2cebfb
https://doi.org/10.1016/j.nucmedbio.2017.12.005
https://doi.org/10.1016/j.nucmedbio.2017.12.005
Publikováno v:
Endocrine. 72(2)
Platelet derived growth receptor alpha (PDGFRA) promotes the epithelial-mesenchymal transition (EMT) in thyroid follicular cells and is linked to lymphatic metastases in papillary thyroid cancer (PTC). We probed the regulatory network of genes linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a693cebd4ea051c488eff5f530cf39
https://pubmed.ncbi.nlm.nih.gov/32914379
https://pubmed.ncbi.nlm.nih.gov/32914379
Autor:
David N. Brindley, Esther Ekpe-Adewuyi, Todd P. W. McMullen, Xiaoyun Tang, Ana Lopez-Campistrous
Publikováno v:
Oncotarget
// Esther Ekpe-Adewuyi 1 , Ana Lopez-Campistrous 1 , Xiaoyun Tang 2 , David N. Brindley 2 , Todd P. W. McMullen 1, 3 1 Department of Surgery, University of Alberta, Edmonton, Canada 2 Signal Transduction Research Group, Department of Biochemistry, Un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d87837e7cc5428b21814e9ae6e336a8
https://doi.org/10.18632/oncotarget.13299
https://doi.org/10.18632/oncotarget.13299
Autor:
Peng Wang, Todd P. W. McMullen, Jay Dewald, Raymond Lai, Karen Chu, Matthew G.K. Benesch, Yi Man Ko, David N. Brindley, Esther Ekpe Adewuyi, Sunita Ghosh, Larissa J. Vos, David Williams, Aducio Thiesen, Ana Lopez-Campistrous
Publikováno v:
EBioMedicine
EBioMedicine, Vol 12, Iss C, Pp 86-97 (2016)
EBioMedicine, Vol 12, Iss C, Pp 86-97 (2016)
Dedifferentiation of follicular cells is a central event in resistance to radioactive iodine and patient mortality in papillary thyroid carcinoma (PTC). We reveal that platelet derived growth factor receptor alpha (PDGFRα) specifically drives dediff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397bb2550b262e803b92311244b8f86c
https://doi.org/10.1016/j.ebiom.2016.09.007
https://doi.org/10.1016/j.ebiom.2016.09.007
Autor:
Mireille M. Kattar, Esther Ekpe Adewuyi, Jean Deschenes, Todd P. W. McMullen, Sunita Ghosh, Ana Lopez-Campistrous
Publikováno v:
Human pathology. 75
Metastatic dissemination of papillary thyroid cancer has been reported to be strongly associated with expression of platelet-derived growth factor (PDGFR) α and altered TTF1 function. However, the status of PDGF ligands in papillary thyroid cancer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cc723a6fa2d92076dbeef620d197e3
https://pubmed.ncbi.nlm.nih.gov/29408504
https://pubmed.ncbi.nlm.nih.gov/29408504
Autor:
Yi M. Ko, Yuan Y. Zhao, Jay Dewald, Ana Lopez-Campistrous, Matthew G.K. Benesch, Xiaoyun Tang, Jonathan M. Curtis, Raymond Lai, Todd P. W. McMullen, David N. Brindley
Publikováno v:
Endocrine-Related Cancer. 22:593-607
Autotaxin is a secreted enzyme that converts extracellular lysophosphatidylcholine to lysophosphatidate (LPA). In cancers, LPA increases tumour growth, metastasis and chemoresistance by activating six G-protein coupled receptors. We examined >200 hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46db1137bb00c91eb22535c1d6b1ac1b
https://doi.org/10.1530/erc-15-0045
https://doi.org/10.1530/erc-15-0045