Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Ana Liempi"'
Autor:
Mauricio Moncada-Basualto, Jorge Saavedra-Olavarría, Paula S. Rivero-Jerez, Cristian Rojas, Juan D. Maya, Ana Liempi, Matías Zúñiga-Bustos, Claudio Olea-Azar, Michel Lapier, Edwin G. Pérez, Josué Pozo-Martínez
Publikováno v:
Molecules, Vol 29, Iss 12, p 2762 (2024)
The development of new compounds to treat Chagas disease is imperative due to the adverse effects of current drugs and their low efficacy in the chronic phase. This study aims to investigate nitroisoxazole derivatives that produce oxidative stress wh
Externí odkaz:
https://doaj.org/article/844cfc324c4f4fb9ac782203c4a1138a
Autor:
Javiera Órdenes-Rojas, Paola Risco, José Ortega-Campos, Germán Barriga-González, Ana Liempi, Ulrike Kemmerling, Dinorah Gambino, Lucía Otero, Claudio Olea Azar, Esteban Rodríguez-Arce
Publikováno v:
Inorganics, Vol 12, Iss 5, p 133 (2024)
In the search for a more effective chemotherapy for the treatment of Chagas’ disease, caused by Trypanosoma cruzi parasite, the use of gold compounds may be a promising approach. In this work, four gold(I) compounds [AuCl(HL)], (HL = bioactive 5-ni
Externí odkaz:
https://doaj.org/article/c7171937b9434b69939630d12b86a655
Autor:
Maura Rojas-Pirela, Diego Andrade-Alviárez, Lisvaneth Medina, Christian Castillo, Ana Liempi, Jesús Guerrero-Muñoz, Yessica Ortega, Juan Diego Maya, Verónica Rojas, Wilfredo Quiñones, Paul A. Michels, Ulrike Kemmerling
Publikováno v:
Open Biology, Vol 12, Iss 6 (2022)
MicroRNAs (miRNAs) are a group of small non-coding RNAs present in a wide diversity of organisms. MiRNAs regulate gene expression at a post-transcriptional level through their interaction with the 3′ untranslated regions of target mRNAs, inducing t
Externí odkaz:
https://doaj.org/article/40b08d7fbbbc46b4b231a704f504b82c
Autor:
Josué Pozo-Martínez, Francisco Salgado, Ana Liempi, Ulrike Kemmerling, Raúl Mera-Adasme, Claudio Olea-Azar, Mauricio Moncada-Basualto, Fernanda Borges, Eugenio Uriarte, Maria João Matos
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 3, Pp 103641- (2022)
American trypanosomiasis or Chagas disease is caused by the protozoan parasite Trypanosoma cruzi, and is considered a neglected disease, being an important problem for public health. Benznidazole (BZN) is the drug used to treat the disease. However,
Externí odkaz:
https://doaj.org/article/4e036ff6ec6c46999cf15afec80a6b4b
Autor:
Maura Rojas-Pirela, Diego Andrade-Alviárez, Wilfredo Quiñones, Maria Verónica Rojas, Christian Castillo, Ana Liempi, Lisvaneth Medina, Jesus Guerrero-Muñoz, Alejandro Fernández-Moya, Yessica Andreina Ortega, Sebastián Araneda, Juan Diego Maya, Ulrike Kemmerling
Publikováno v:
Microorganisms, Vol 11, Iss 1, p 61 (2022)
microRNAs (miRNAs) are a group of small non-coding RNAs that regulate gene expression post-transcriptionally through their interaction with the 3′ untranslated regions (3′ UTR) of target mRNAs, affecting their stability and/or translation. Theref
Externí odkaz:
https://doaj.org/article/142e9dca5b71476bb0d22dd164d57e98
Autor:
Francisco Salgado, Mauricio Moncada-Basualto, Josue Pozo-Martinez, Ana Liempi, Ulrike Kemmerling, Juan-Diego Maya, Pablo Jaque, Fernanda Borges, Eugenio Uriarte, Maria J. Matos, Claudio Olea-Azar
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 3, Pp 102975- (2021)
Chagas disease is the most widespread contagious tropical disease in Latin America, being an important public health problem. Treatments against this disease are still very ineffective, presenting several side effects. Therefore, the search for alter
Externí odkaz:
https://doaj.org/article/ac8e2a9465f14e32bb336d3f209757ca
Autor:
Lisvaneth Medina, Christian Castillo, Ana Liempi, Jesús Guerrero-Muñoz, Maura Rojas-Pirela, Juan Diego Maya, Humberto Prieto, Ulrike Kemmerling
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Trypanosoma cruzi and Toxoplasma gondii are two parasites than can be transmitted from mother to child through the placenta. However, congenital transmission rates are low for T. cruzi and high for T. gondii. Infection success or failure depends on c
Externí odkaz:
https://doaj.org/article/a3ca6468b87c4fb6a966d42640b5313b
Autor:
Florencia Díaz-Viraqué, María Laura Chiribao, Andrea Trochine, Fabiola González-Herrera, Christian Castillo, Ana Liempi, Ulrike Kemmerling, Juan Diego Maya, Carlos Robello
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The discovery that trypanosomatids, unicellular organisms of the order Kinetoplastida, are capable of synthesizing prostaglandins raised questions about the role of these molecules during parasitic infections. Multiple studies indicate that prostagla
Externí odkaz:
https://doaj.org/article/fa0bd5f7ee1e49a086af8d6ae1eb2a40
Autor:
Lisvaneth Medina, Jesús Guerrero-Muñoz, Christian Castillo, Ana Liempi, Alejandro Fernández-Moya, Sebastian Araneda, Yessica Ortega, Cristian Rivas, Juan Diego Maya, Ulrike Kemmerling
Publikováno v:
Acta tropica. 235
Trypanosoma cruzi and Toxoplasma gondii are two zoonotic parasites that constitute significant human and animal health threats, causing a significant economic burden worldwide. Both parasites can be transmitted congenitally, but transmission rates fo
Autor:
null Maura Rojas-Pirela, null Diego Andrade-Alviárez, null Lisvaneth Medina, null Christian Castillo, null Ana Liempi, null Jesús Guerrero-Muñoz, null Yessica Ortega, null Juan Diego Maya, null Verónica Rojas, null Wilfredo Quiñones, null Paul A. Michels, null Ulrike Kemmerling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1230a2e578153c77430d96751019aced
https://doi.org/10.1098/rsob.210395/v3/response1
https://doi.org/10.1098/rsob.210395/v3/response1