Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ana Lia, Mazzeti"'
Autor:
Fernanda Fortes de Araujo, Rana Nagarkatti, Ana Lia Mazzeti, Karolina Ribeiro Gonçalves, Lívia de Figueiredo Diniz, Isabela Campos do Vale, Olindo Assis Martins-Filho, Alain Debrabant, Maria Terezinha Bahia, Andréa Teixeira-Carvalho
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionChagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi. Although endemic mainly in Latin America, CD has become a global public health problem due to migration of infected individuals to non-endemic regions. Despite pro
Externí odkaz:
https://doaj.org/article/60fe01f1e4f84f4b87ea28d4a4c2b88a
Autor:
Gabriela Rodrigues Leite, Denise da Gama Jaén Batista, Ana Lia Mazzeti, Rosemeire Aparecida Silva, Ademar Benévolo Lugão, Maria de Nazaré Correia Soeiro
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chagas disease (CD), caused by the hemoflagellate protozoan Trypanosoma cruzi, affects more than six million people worldwide and presents an unsatisfactory therapy, based on two nitroderivatives, introduced in clinical medicine for decades. The synt
Externí odkaz:
https://doaj.org/article/e304bd7515be497587af4f0f5161c81a
Autor:
Ana Lia Mazzeti, Karolina R. Gonçalves, Patrícia Ferreira Boasquívis, Jamile Barbosa, Bruno G. Pereira, Maria de Nazaré Correia Soeiro, Vanessa Carla Furtado Mosqueira, Maria Terezinha Bahia
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1126 (2023)
Benznidazole (BZ) tablets are the currently prescribed treatment for Chagas disease. However, BZ presents limited efficacy and a prolonged treatment regimen with dose-dependent side effects. The design and development of new BZ subcutaneous (SC) impl
Externí odkaz:
https://doaj.org/article/fe3dca29a4dd4ee6a2e82586b06e2304
Autor:
Mayra Fernanda Ricci, Samantha Ribeiro Béla, Michele Macedo Moraes, Maria Terezinha Bahia, Ana Lia Mazzeti, Anny Carolline Silva Oliveira, Luciana Oliveira Andrade, Rafael Radí, Lucía Piacenza, Rosa Maria Esteves Arantes
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
There is a growing consensus that the balance between the persistence of infection and the host immune response is crucial for chronification of Chagas heart disease. Extrapolation for chagasic megacolon is hampered because research in humans and ani
Externí odkaz:
https://doaj.org/article/1a6409a20bce48039dd3b9daa21ebc09
Autor:
Lívia de Figueiredo Diniz, Karolina R. Gonçalves, Dario Elias Pereira, Suianne Leticia Antunes Mota, Maria Terezinha Bahia, Ana Lia Mazzeti
Publikováno v:
Parasitology. 148:1320-1327
Drug combinations have been evaluated for Chagas disease in an attempt to improve efficacy and safety. In this line, the objective of this work is to assess the effects of treatment with nitro drugs combinations using benznidazole (BZ) or nifurtimox
Autor:
Ana Lia Mazzeti, Vanessa Carla Furtado Mosqueira, Maria Terezinha Bahia, Patricia Capelari-Oliveira
Publikováno v:
Journal of Experimental Pharmacology
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are available for the treatment of Chagas disease, with limitations such as variable e
Autor:
Izabella Spindola Torres, Lindamar Maria de Souza, Ana Lia Mazzeti, Luis Fernando Viana Furtado
Publikováno v:
Open Science Research VIII ISBN: 9786553602342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c23b00d0a153da20fbe6dde774e11385
https://doi.org/10.37885/221110915
https://doi.org/10.37885/221110915
Autor:
Cai, Lin, Denise da Gama, Jaén Batista, Ana Lia, Mazzeti, Roberson, Donola Girão, Gabriel Melo, de Oliveira, Izet, Karalic, Fabian, Hulpia, Maria de Nazaré C, Soeiro, Louis, Maes, Guy, Caljon, Serge, Van Calenbergh
Publikováno v:
European journal of medicinal chemistry. 231
Chagas disease and leishmaniasis are two poverty-related neglected tropical diseases that cause high mortality and morbidity. Current treatments suffer from severe limitations and novel, safer and more effective drugs are urgently needed. Both Trypan
Autor:
Natália Lins da Silva Gomes, Camila Cardoso-Santos, Ana Lia Mazzeti, Ludmila Ferreira de Almeida Fiuza, Denise da Gama Jaen Batista, Cristiane França da Silva, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro, Guy Caljon, Otacilio C. Moreira, Gabriel Melo de Oliveira, Louis Maes, Fabian Hulpia, Roberson Donola Girão
Publikováno v:
JAC-ANTIMICROBIAL RESISTANCE
JAC-Antimicrobial Resistance
JAC-Antimicrobial Resistance
Background The protozoan Trypanosoma cruzi is auxotrophic for purines and causes Chagas’ disease (CD), a neglected illness affecting >6 million people. Combining the 3-deoxyribofuranose part of cordycepin with the modified purine ring of a nucleosi
Autor:
Camila, Cardoso-Santos, Ludmila, Ferreira de Almeida Fiuza, Cristiane, França da Silva, Ana Lia, Mazzeti, Roberson, Donola Girão, Gabriel, Melo de Oliveira, Denise, da Gama Jaen Batista, Otacilio, Cruz Moreira, Natália, Lins da Silva Gomes, Louis, Maes, Guy, Caljon, Fabian, Hulpia, Serge V, Calenbergh, Maria de Nazaré, Correia Soeiro
Publikováno v:
JAC-Antimicrobial Resistance
Background The protozoan Trypanosoma cruzi is auxotrophic for purines and causes Chagas’ disease (CD), a neglected illness affecting >6 million people. Combining the 3-deoxyribofuranose part of cordycepin with the modified purine ring of a nucleosi