Effects of Serine or Threonine in the Active Site of Typical 2-Cys Prx on Hyperoxidation Susceptibility and on Chaperone Activity

Autor: Carlos A. Tairum, Melina Cardoso Santos, Carlos Alexandre Breyer, Ana Laura Pires de Oliveira, Vitoria Isabela Montanhero Cabrera, Guilherme Toledo-Silva, Gustavo Maruyama Mori, Marcos Hikari Toyama, Luis Eduardo Soares Netto, Marcos Antonio de Oliveira

Publikováno v: Antioxidants, Vol 10, Iss 7, p 1032 (2021)

Typical 2-Cys peroxiredoxins (2-Cys Prx) are ubiquitous Cys-based peroxidases, which are stable as decamers in the reduced state, and may dissociate into dimers upon disulfide bond formation. A peroxidatic Cys (CP) takes part of a catalytic triad, to

Externí odkaz: https://doaj.org/article/f8b742f6bdfe48deaedab6dc8bf98611

Effects of Serine or Threonine in the Active Site of Typical 2-Cys Prx on Hyperoxidation Susceptibility and on Chaperone Activity

Autor: Carlos Alexandre Breyer, Carlos A. Tairum, Melina Cardoso dos Santos, Marcos H. Toyama, Ana Laura Pires de Oliveira, Gustavo Maruyama Mori, Luis Eduardo Soares Netto, Guilherme Toledo-Silva, Marcos Antonio de Oliveira, Vitoria Isabela Montanhero Cabrera

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Antioxidants
Volume 10
Issue 7
Antioxidants, Vol 10, Iss 1032, p 1032 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2022-05-01T05:29:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Typical 2-Cys peroxiredoxins (2-Cys Prx) are ubiquitous Cys-based peroxidas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa7ce41ebe0dbcaada1e1afcd2780f0

Presence of Ser instead of Thr in the Catalytic Triad of Typical 2-Cys Prx Increases their Resistance to Hyperoxidation and Inactivation

Autor: M. A Oliveira, Gustavo Maruyama Mori, Carlos A. Tairum, Melina Cardoso dos Santos, Marcos H. Toyama, Vitória Isabela Montanhero, Carlos Alexandre Breyer, Ohara Augusto, Luis Eduardo Soares Netto, Guilherme Toledo-Silva, Ana Laura Pires de Oliveira

Publikováno v: Free Radical Biology and Medicine. 159:S34

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::741068bf5e189a47c228c37eb357425a
https://doi.org/10.1016/j.freeradbiomed.2020.10.099