Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ana Lapao"'
Autor:
Matthew Yoke Wui Ng, Chara Charsou, Ana Lapao, Sakshi Singh, Laura Trachsel-Moncho, Sebastian W. Schultz, Sigve Nakken, Michael J. Munson, Anne Simonsen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The functions of specific lipids in autophagosome biogenesis are not entirely clear. Here, the authors show that the ER protein GRAMD1C, a cholesterol transport protein, suppresses autophagy initiation and has roles in mitochondrial cholesterol homeo
Externí odkaz:
https://doaj.org/article/e7fede4d4b1c4ef589afdf61c6e3f288
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Autophagy
instname
Autophagy
37 p.-3 fig.-1 tab.
Mitochondria are dynamic, multifunctional cellular organelles that play a fundamental role in maintaining cellular homeostasis. Keeping the quality of mitochondria in check is of essential importance for functioning and survi
Mitochondria are dynamic, multifunctional cellular organelles that play a fundamental role in maintaining cellular homeostasis. Keeping the quality of mitochondria in check is of essential importance for functioning and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21671ad80063fb2148c17907f5f8f414
https://doi.org/10.1080/15548627.2021.1888244
https://doi.org/10.1080/15548627.2021.1888244
Autor:
Sakshi Singh, Laura Trachsel-Moncho, Matthew Yoke Wui Ng, Michael J. Munson, Anne Simonsen, C. Charsou, Ana Lapao, Sigve Nakken
During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called autophagosomes. The origin and identity of the membranes that form the autophagosome remain to be fully characterized. Here, we investigated the role of cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89959ed80d7431dc16074014fcb2c9a
https://doi.org/10.1101/2021.08.04.455032
https://doi.org/10.1101/2021.08.04.455032
Autor:
Matthew Yoke Wui Ng, Chara Charsou, Ana Lapao, Sakshi Singh, Laura Trachsel-Moncho, Sebastian W. Schultz, Sigve Nakken, Michael J. Munson, Anne Simonsen
Publikováno v:
Nature communications. 13(1)
During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called autophagosomes. The contributions of specific lipids, such as cholesterol, to the membranes that form the autophagosome, remain to be fully characterized. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3b05e9ff09e612d1c424b6a2fe897f
https://pubmed.ncbi.nlm.nih.gov/36270994
https://pubmed.ncbi.nlm.nih.gov/36270994
Autor:
Katja Parapatics, Robert Kralovics, Ferran Fece de la Cruz, Tilmann Bürckstümmer, Florian M. Pauler, Claudia Kerzendorfer, Richard Schobesberger, Philipp M. Guenzl, Jacques Colinge, Sylvia Knapp, Gustav Ammerer, Vincent A. Blomen, Barbara B. Maier, Carina Banning, Keiryn L. Bennett, Melissa Liszt, Tomasz Konopka, Wolfgang Fischl, M Rita Taba Casari, Philipp Hainzl, Michal Smida, Sejla Salic, Ana Lapao, Georg Casari, Christoph Bock, Johannes Stöckl, Benjamin Eizinger, Doris Chen, Bianca V. Gapp, Manuele Rebsamen, Thijn R. Brummelkamp, Giulio Superti-Furga, Sebastian M.B. Nijman, Fiorella Schischlik, Nicole C.C. Them
Knockout collections are invaluable tools for studying model organisms such as yeast. However, there are no large-scale knockout collections of human cells. Using gene-trap mutagenesis in near-haploid human cells, we established a platform to generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7533ddac3be5058b432f6c7a5f0bcb
https://ora.ox.ac.uk/objects/uuid:64ba4455-e427-49bf-9273-12e27fa7eaa8
https://ora.ox.ac.uk/objects/uuid:64ba4455-e427-49bf-9273-12e27fa7eaa8
Publikováno v:
BMC Genomics
Background Chromosomal translocations are a hallmark of cancer cells and give rise to fusion oncogenes. To gain insight into the mechanisms governing tumorigenesis, adequate model cell lines are required. Results We employ the versatile CRISPR/Cas sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26eaf726c0c25d46ceaba24cddc60cce