Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ana L. Perdigoto"'
Autor:
Dijana Djureinovic, Sarah A. Weiss, Irina Krykbaeva, Rihao Qu, Ioannis Vathiotis, Myrto Moutafi, Lin Zhang, Ana L. Perdigoto, Wei Wei, Gail Anderson, William Damsky, Michael Hurwitz, Barbara Johnson, David Schoenfeld, Amit Mahajan, Frank Hsu, Kathryn Miller-Jensen, Yuval Kluger, Mario Sznol, Susan M. Kaech, Marcus Bosenberg, Lucia B. Jilaveanu, Harriet M. Kluger
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Stimulating inflammatory tumor associated macrophages can overcome resistance to PD-(L)1 blockade. We previously conducted a phase I trial of cabiralizumab (anti-CSF1R), sotigalimab (CD40-agonist) and nivolumab. Our current purpos
Externí odkaz:
https://doaj.org/article/4fa1a648e79343f59ea5d04accc2e62b
Autor:
Mei-Ling Yang, Sheryl Horstman, Renelle Gee, Perrin Guyer, TuKiet T. Lam, Jean Kanyo, Ana L. Perdigoto, Cate Speake, Carla J. Greenbaum, Aïsha Callebaut, Lut Overbergh, Richard G. Kibbey, Kevan C. Herold, Eddie A. James, Mark J. Mamula
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Post translational modifications are involved in the regulation of a number of proteins and can be themselves modified by the cellular environment. Here the authors implicate citrullination of glucokinase in autoimmune diabetes
Externí odkaz:
https://doaj.org/article/05c25682e0244aef9cf1385fd566a122
Autor:
Dijana Djureinovic, Sarah A. Weiss, Irina Krykbaeva, Rihao Qu, Ioannis Vathiotis, Myrto Moutafi, Lin Zhang, Ana L. Perdigoto, Wei Wei, Gail Anderson, William Damsky, Michael Hurwitz, Barbara Johnson, Amit Mahajan, Frank Hsu, Kathryn Miller-Jensen, Yuval Kluger, Mario Sznol, Susan M. Kaech, Marcus Bosenberg, Lucia Jilaveanu, Harriet M. Kluger
Publikováno v:
Cancer Research. 83:3287-3287
Stimulating innate immunity can potentially enable us to overcome resistance to PD-(L)1 blockade. We previously conducted a phase 1 trial of cabiralizumab (anti-CSF1R) with sotigalimab (CD40 agonistic antibody) and nivolumab. Our purpose was to deter
Autor:
Mei-Ling, Yang, Sheryl, Horstman, Renelle, Gee, Perrin, Guyer, TuKiet T, Lam, Jean, Kanyo, Ana L, Perdigoto, Cate, Speake, Carla J, Greenbaum, Aïsha, Callebaut, Lut, Overbergh, Richard G, Kibbey, Kevan C, Herold, Eddie A, James, Mark J, Mamula
Publikováno v:
Nature communications. 13(1)
Inflammation, including reactive oxygen species and inflammatory cytokines in tissues amplify various post-translational modifications of self-proteins. A number of post-translational modifications have been identified as autoimmune biomarkers in the
Autor:
Chunyao Wei, Elizabeth J Thatcher, Abigail F Olena, Diana J Cha, Ana L Perdigoto, Andrew F Marshall, Bruce D Carter, Kendal Broadie, James G Patton
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57080 (2013)
SNAP-25 is a core component of the trimeric SNARE complex mediating vesicle exocytosis during membrane addition for neuronal growth, neuropeptide/growth factor secretion, and neurotransmitter release during synaptic transmission. Here, we report a no
Externí odkaz:
https://doaj.org/article/d18a6b9f2a2049228361418967b1201b
Publikováno v:
Cardiovascular endocrinology. 6(2)
Insulin resistance, a fundamental pathophysiological abnormality in patients with type 2 diabetes, is associated with increased cardiovascular (CV) disease risk. In diabetes management, the macrovascular impact of antihyperglycemic agents that do not
Autor:
Bruce D. Carter, Nagarathnamma Chaudhry, Gregory N. Barnes, Ana L. Perdigoto, Marie T. Filbin
Publikováno v:
Molecular and Cellular Neuroscience. 46:235-244
Axonal regeneration in the central nervous system is prevented, in part, by inhibitory proteins expressed by myelin, including Myelin-associated glycoprotein (MAG). Although injury to the corticospinal tract can result in permanent disability, little
Autor:
Abigail F. Olena, Andrew F. Marshall, Chunyao Wei, Ana L. Perdigoto, James G. Patton, Kendal Broadie, Elizabeth J. Thatcher, Diana J. Cha, Bruce D. Carter
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e57080 (2013)
PLoS ONE, Vol 8, Iss 2, p e57080 (2013)
SNAP-25 is a core component of the trimeric SNARE complex mediating vesicle exocytosis during membrane addition for neuronal growth, neuropeptide/growth factor secretion, and neurotransmitter release during synaptic transmission. Here, we report a no
Autor:
Ty W. Abel, Bruce D. Carter, Ambra Pozzi, Annukka A.R. Antar, Terence S. Dermody, Rachel A. Henry, Jacquelyn A. Campbell, Ana L. Perdigoto, Jennifer L. Konopka
Publikováno v:
Cell Host & Microbe. (1):59-71
SummaryDiverse families of viruses bind immunoglobulin superfamily (IgSF) proteins located in tight junctions (TJs) and adherens junctions of epithelium and endothelium. However, little is known about the roles of these receptors in the pathogenesis