Endothelial Dysfunction Is Related to Monocyte Activation in Antiretroviral-Treated People With HIV and HIV-Negative Adults in Kenya

Autor: Ana L. Gervassi, John R. Koethe, Sarah Masyuko, Stephanie T. Page, Celestine N. Wanjalla, Stephen J. Polyak, Jerusha Nyabiage, Tecla M Temu, Carey Farquhar, Jerry S Zifodya, John Kinuthia, Julius Oyugi

Publikováno v: Open Forum Infectious Diseases

Background Residual monocyte activation may contribute to increased risk for endothelial dysfunction and subsequent atherosclerotic cardiovascular diseases (CVDs) among people with HIV (PWH) on antiretroviral therapy (ART). We examined the relationsh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313a0f7b0d0855244b7fb8809eb4fe85
http://europepmc.org/articles/PMC7568437

Is Infant Immunity Actively Suppressed or Immature?

Autor: Ana L. Gervassi, Helen Horton

Publikováno v: Virology: Research and Treatment, Vol 2014, Iss 5, Pp 1-9 (2014)
Virology : Research and Treatment
Virology: Research and Treatment, Vol 5 (2014)

Almost 7 million children under the age 5 die each year, and most of these deaths are attributable to vaccine-preventable infections. Young infants respond poorly to infections and vaccines. In particular, dendritic cells secrete less IL-12 and IL-18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49547a41b4e298e8de2052d3adfd71c5
http://www.la-press.com/is-infant-immunity-actively-suppressed-or-immature-article-a4086

Human CD8+ T Cells Recognize the 60-kDa Cysteine-Rich Outer Membrane Protein from Chlamydia trachomatis

Autor: Ana L. Gervassi, Peter Probst, Steven P. Fling, Bruce W. Hess, Kenneth H. Grabstein, Mark R. Alderson

Publikováno v: The Journal of Immunology. 173:6905-6913

The intracellular bacterial pathogen Chlamydia is sequestered from the host cell cytoplasm by remaining within an inclusion body during its replication cycle. Nevertheless, CD8+ T cells recognizing Chlamydia Ags in the context of MHC class I molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b78fe9c4b2a189ca27b938fc70b4ea9
https://doi.org/10.4049/jimmunol.173.11.6905

Myeloid derived suppressor cells are present at high frequency in neonates and suppress in vitro T cell responses

Autor: Helen Horton, Grace Itaya, Heather B. Jaspan, Nicholas Lejarcegui, Elvis B. Kidzeru, Soren Gantt, Sandra Dross, Ana L. Gervassi, Amanda C. Jacobson

Publikováno v: PLoS One
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e107816 (2014)

Over 4 million infants die each year from infections, many of which are vaccine-preventable. Young infants respond relatively poorly to many infections and vaccines, but the basis of reduced immunity in infants is ill defined. We sought to investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9870400fb5f554191c30fb5bae76dda7
http://hdl.handle.net/11427/15323

IN VITRO RECALL OF PROLIFERATIVE AND CYTOLYTIC RESPONSES TO MINOR HISTOCOMPATIBILITY ANTIGENS BY DENDRITIC CELL ENRICHED CANINE PERIPHERAL BLOOD MONONUCLEAR CELLS

Autor: Michael A. Bean, Ana L. Gervassi, Rainer Storb, Jacquelynn S. White, Peter Kalhs

Publikováno v: Transplantation. 59:112-118

It is difficult in vitro to demonstrate existent in vivo sensitization of dogs and humans to minor histocompatibility antigens. Using conventional one-way mixed leukocyte culture, when sensitized blood cells are stimulated with MHC antigen-matched si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1e719c6f2878d403589e36bde48d6f
https://doi.org/10.1097/00007890-199501150-00020