Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ana Justino"'
Autor:
Maria Gabriela O. Fernandes, Catarina Sousa, Joana Pereira Reis, Natália Cruz-Martins, Conceição Souto Moura, Susana Guimarães, Ana Justino, Maria João Pina, Adriana Magalhães, Henrique Queiroga, José Agostinho Marques, José Carlos Machado, José Luís Costa, Venceslau Hespanhol
Publikováno v:
Cells, Vol 10, Iss 8, p 1912 (2021)
Introduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising and resistance mutations in advanced Non-Small Cell Lung Cancer (NSCLC) patients. Next-generation sequencing (NGS) of circulating free DNA (cfDNA) is a
Externí odkaz:
https://doaj.org/article/cb45f69c6b824d58a00d44bd18661267
Autor:
Maria Gabriela O. Fernandes, Natália Cruz-Martins, Conceição Souto Moura, Susana Guimarães, Joana Pereira Reis, Ana Justino, Maria João Pina, Adriana Magalhães, Henrique Queiroga, José Carlos Machado, Venceslau Hespanhol, José Luis Costa
Publikováno v:
Cancers, Vol 13, Iss 11, p 2707 (2021)
Background: Analysis of circulating tumor DNA (ctDNA) has remarkable potential as a non-invasive lung cancer molecular diagnostic method. This prospective study addressed the clinical value of a targeted-gene amplicon-based plasma next-generation seq
Externí odkaz:
https://doaj.org/article/d87eda1ee69b45a999e65b3d40477fda
Autor:
Maria Gabriela O. Fernandes, Maria Jacob, Natália Martins, Conceição Souto Moura, Susana Guimarães, Joana Pereira Reis, Ana Justino, Maria João Pina, Luís Cirnes, Catarina Sousa, Josué Pinto, José Agostinho Marques, José Carlos Machado, Venceslau Hespanhol, José Luis Costa
Publikováno v:
Cancers, Vol 11, Iss 9, p 1229 (2019)
Identification of targetable molecular changes is essential for selecting appropriate treatment in patients with advanced lung adenocarcinoma. Methods: In this study, a Sanger sequencing plus Fluorescence In Situ Hybridization (FISH) sequential appro
Externí odkaz:
https://doaj.org/article/ffde8d41d0514c6390b8218e2d57fde3
Autor:
Conceição Souto Moura, Maria João Pina, Venceslau Hespanhol, Ana Justino, Maria Gabriela O Fernandes, Henrique Queiroga, José Agostinho Marques, Catarina Sousa, Adriana Magalhães, Joana Pereira Reis, Natália Cruz-Martins, José Carlos Machado, José Luis Costa, Susana Guimarães
Publikováno v:
Cells, Vol 10, Iss 1912, p 1912 (2021)
Cells
Volume 10
Issue 8
Cells
Volume 10
Issue 8
Introduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising and resistance mutations in advanced Non-Small Cell Lung Cancer (NSCLC) patients. Next-generation sequencing (NGS) of circulating free DNA (cfDNA) is a
Autor:
Natália Cruz-Martins, Joana Pereira Reis, Henrique Queiroga, Susana Guimarães, Conceição Souto Moura, Ana Justino, José Luis Costa, Adriana Magalhães, Maria Gabriela O Fernandes, José Carlos Machado, Maria João Pina, Venceslau Hespanhol
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2707, p 2707 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2707, p 2707 (2021)
Background: Analysis of circulating tumor DNA (ctDNA) has remarkable potential as a non-invasive lung cancer molecular diagnostic method. This prospective study addressed the clinical value of a targeted-gene amplicon-based plasma next-generation seq
Autor:
Venceslau Hespanhol, Ana Justino, Maria Jacob, Conceição Souto Moura, Maria Gabriela O Fernandes, Maria João Pina, Susana Guimarães, Joana Pereira Reis, José Agostinho Marques, Catarina Sousa, José Carlos Machado, José Luis Costa, Luis Cirnes, Josué Pinto, Natália Martins
Publikováno v:
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1229 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1229 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Identification of targetable molecular changes is essential for selecting appropriate treatment in patients with advanced lung adenocarcinoma. Methods: In this study, a Sanger sequencing plus Fluorescence In Situ Hybridization (FISH) sequential appro
Autor:
Ana Justino, José Carlos Machado, Sónia Sousa, Patrícia Dias, Luis Cirnes, Maria João Pina, José Luis Costa, Ana Berta Sousa
Publikováno v:
European Journal of Human Genetics. 23:347-353
Variants in 11 genes of the RAS/MAPK signaling pathway have been causally linked to the neuro-cardio-facio-cutaneous syndromes group (NCFCS). Recently, A2ML1 and RIT1 were also associated with these syndromes. Because of the genetic and clinical hete
Autor:
Fernando Schmitt, Sónia Sousa, Ana Justino, Susana Fernandes, Luis Cirnes, José Carlos Machado, Teresa Kay, José Luis Costa
Publikováno v:
Human mutation. 34(4)
The introduction of the benchtop massive parallel sequencers made it possible for the majority of clinical diagnostic laboratories to gain access to this fast evolving technology. In this study, using the Ion Torrent Personal Genome Machine, we prese
Autor:
José Carlos Machado, Gabriela Fernandes, José Luis Costa, Bárbara Parente, Ana Justino, Ana Barroso, Venceslau Hespanhol
Publikováno v:
Cancer Research. 75:4930-4930
The identification of mutations in circulating tumor DNA (ctDNA) can serve as a biomarker for non-invasive diagnosis and real time therapeutic monitoring. Although next generation sequencing (NGS) is a promising technology, the intrinsic low abundanc
Publikováno v:
Cancer Research. 74:1512-1512
Tumor-specific (somatic) mutations in plasma can serve as biomarkers for tumor detection, monitor tumor response to specific therapies, detect residual disease after surgery, and long-term follow-up. The intrinsic low abundance of circulating cell-fr