Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ana Jimenez-Valverde"'
Autor:
Katharine E. Stott, Jason T. Mohabir, Katharine Bowers, Jennifer L. Tenor, Dena L. Toffaletti, Jennifer Unsworth, Ana Jimenez-Valverde, Ajisa Ahmadu, Melanie Moyo, Ebbie Gondwe, Wezi Chimang’anga, Madalitso Chasweka, David S. Lawrence, Joseph N. Jarvis, Tom Harrison, William Hope, David G. Lalloo, Henry C. Mwandumba, John R. Perfect, Christina A. Cuomo
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Cryptococcal meningitis causes an estimated 112,000 global deaths per annum. Genomic and phenotypic features of the infecting strain of Cryptococcus spp. have been associated with outcomes from cryptococcal meningitis. Additionally, populati
Externí odkaz:
https://doaj.org/article/5c0a7db0000344608f0923009f12b36b
Autor:
Nicola Farrington, Vineet Dubey, Adam Johnson, Iona Horner, Adam Stevenson, Jennifer Unsworth, Ana Jimenez-Valverde, Julie Schwartz, Shampa Das, William Hope, Christopher A. Darlow
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Hospital-acquired pneumonia (HAP) is a leading cause of morbidity and mortality, commonly caused by Pseudomonas aeruginosa. Meropenem is a commonly used therapeutic agent, although emergent resistance occurs during treatment. We used a rabbi
Externí odkaz:
https://doaj.org/article/e7876836b0d34c8b84fc88a01c14479d
Autor:
Christopher Darlow, Nicola Farrington, Laura McEntee, Adam Johnson, Jennifer Unsworth, Ana Jimenez-Valverde, Bhavana Jagota, Fernando Docobo-Perez, Ruwanthi Kolamunnage-Dona, Renata de Costa, Sally Ellis, François Franceschi, Mike Sharland, Michael Neely, Laura Piddock, Shampa Das, William Hope
Publikováno v:
Clinical Infection in Practice, Vol 15, Iss , Pp 100191- (2022)
Externí odkaz:
https://doaj.org/article/805a26e392f348a4aabcfa3f43b35f29
Autor:
Katharine E Stott, Ajisa Ahmadu, Cheusisime Kajanga, Melanie Moyo, Ebbie Gondwe, Wezzie Chimang’anga, Madalitso Chasweka, Jennifer Unsworth, Ana Jimenez-Valverde, Bhavana Jagota, Reya V Shah, David S Lawrence, David G Lalloo, Tom Harrison, Joseph N Jarvis, William Hope, Henry C Mwandumba
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:1015-1022
Background There are limited data describing clinical flucytosine pharmacokinetics (PK). The variability of flucytosine partitioning into the CNS is not known. We described the interindividual variability in flucytosine PK in patients with HIV-associ
Autor:
Katharine E Stott, Melanie Moyo, Ajisa Ahmadu, Cheusisime Kajanga, Ebbie Gondwe, Wezzie Chimang’anga, Madalitso Chasweka, Tshepo B Leeme, Mooketsi Molefi, Awilly Chofle, Gabriella Bidwell, John Changalucha, Jenny Unsworth, Ana Jimenez-Valverde, David S Lawrence, Henry C Mwandumba, David G Lalloo, Thomas S Harrison, Joseph N Jarvis, William Hope, Anne-Grete Märtson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:276-283
Background Single, high-dose liposomal amphotericin B (LAmB; AmBisome, Gilead Sciences) has demonstrated non-inferiority to amphotericin B deoxycholate in combination with other antifungals for averting all-cause mortality from HIV-associated cryptoc
Autor:
Christopher A Darlow, Laura McEntee, Adam Johnson, Nicola Farrington, Jennifer Unsworth, Ana Jimenez-Valverde, Bhavana Jagota, Ruwanthi Kolamunnage-Dona, Renata M A Da Costa, Sally Ellis, François Franceschi, Mike Sharland, Michael Neely, Laura Piddock, Shampa Das, William Hope
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:3349-3357
Background Annual mortality from neonatal sepsis is an estimated 430 000–680 000 infants globally, most of which occur in low- and middle-income countries (LMICs). The WHO currently recommends a narrow-spectrum β-lactam (e.g. ampicillin) and genta
Autor:
Christopher A. Darlow, Nicola Farrington, Adam Johnson, Laura McEntee, Jennifer Unsworth, Ana Jimenez-Valverde, Ruwanthi Kolamunnage-Dona, Renata M A Da Costa, Sally Ellis, François Franceschi, Mike Sharland, Michael Neely, Laura J. V. Piddock, Shampa Das, William Hope
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1334-1343
Background Neonatal sepsis is a serious bacterial infection of neonates, globally killing up to 680 000 babies annually. It is frequently complicated by antimicrobial resistance, particularly in low- and middle-income country (LMIC) settings with wid
Autor:
Nicola Farrington, Laura McEntee, Adam Johnson, Jennifer Unsworth, Christopher Darlow, Ana Jimenez-Valverde, Christoph Hornik, Rachel Greenberg, Julie Schwartz, Shampa Das, William Hope
Publikováno v:
Antimicrob Agents Chemother
Neonatal sepsis is an underrecognized burden on health care systems throughout the world. Antimicrobial drug resistance (AMR) is increasingly prevalent and compromises the use of currently recommended first-line agents. The development of new antimic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9792577ca3ef52721916eb6c1a9239
https://europepmc.org/articles/PMC9017387/
https://europepmc.org/articles/PMC9017387/
Autor:
Laura McEntee, Nicola Farrington, Joseph F. Standing, Michael Neely, Jennifer Unsworth, Renata M A de Costa, Laura J. V. Piddock, Ruwanthi Kolamunnage-Dona, William W. Hope, Francois Franceschi, Sally Ellis, Ana Jimenez-Valverde, Christopher A Darlow, Shampa Das, Mike Sharland, Adam Johnson, Fernando Docobo-Pérez, Silke Gastine
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrob Agents Chemother
Antimicrob Agents Chemother
Antimicrobial resistance (particularly through extended-spectrum β-lactamase and aminoglycoside-modifying enzyme production) in neonatal sepsis is a global problem, particularly in low- and middle-income countries, with significant mortality rates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8292236546aa47e7bc7e9ece12722ea5
Autor:
Magdalena Zalacain, Shampa Das, Laura McEntee, Nicola Farrington, Ana Jimenez-Valverde, William W. Hope, Martin Everett, Laethitia Alibaud, Jennifer Unsworth, Adam Johnson, Adam Kirby, Carole A. Sable, Ruwanthi Kolamunnage-Dona, Justine Bousquet
Publikováno v:
Antimicrob Agents Chemother
Enterobacteriaceae that produce metallo-β-lactamases (MBLs) are an emerging threat to public health. The metallo-β-lactamase inhibitor (MBLi) ANT2681 inhibits the enzymatic activity of MBLs through interaction with the dinuclear zinc ion cluster pr