Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ana Jardon Alvarez"'
Autor:
Renate Hausinger, Marianne Hackl, Ana Jardon Alvarez, Miriam Kehr, Sandra Romero Marquez, Franziska Hettler, Christian Kehr, Sandra Grziwok, Christina Schreck, Christian Peschel, Rouzanna Istvánffy, Robert A. J. Oostendorp
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 2, Pp 521-532 (2021)
Abstract In this study, we investigated the influence of the loss of cathepsin K (Ctsk) gene on the hematopoietic system in vitro and in vivo. We found that cultures with lineage− SCA1+ KIT+ (LSK) cells on Ctsk deficient stromal cells display reduc
Externí odkaz:
https://doaj.org/article/dbdacb8b9eb74afd8f5bc33fc9befd35
Autor:
Jörg Mages, Dirk H. Busch, Monika Kröger, Christian Peschel, Matthias Schiemann, Kerstin Gauthier, Jonas Renström, Rouzanna Istvanffy, Roland Lang, Ana Jardon-Alvarez, Akihiko Shimono, Robert A.J. Oostendorp, Irene Esposito
Publikováno v:
Cell stem cell. 5(2)
Summary Secreted frizzled-related protein 1 ( Sfrp1 ) is highly expressed by stromal cells maintaining hematopoietic stem cells (HSCs). Sfrp1 loss in stromal cells increases production of hematopoietic progenitors, and in knockout mice, dysregulates