Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ana J. Moreno-Ortega"'
Autor:
Lamia Mouhid Al-achbili, María F. Cano-Abad, Ana Ruiz-Nuño, Ana J. Moreno-Ortega, Jorge Matías-Guiu
Publikováno v:
Neuroscience Letters. 633:28-32
Therapeutic options for amyotrophic lateral sclerosis (ALS) are scarce and controversial. Although the aetiology of neuronal vulnerability is unknown, growing evidence supports a complex network in which multiple toxicity pathways, rather than a sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92984f604b7b55596b65ba3ca248f94b
https://doi.org/10.1016/j.neulet.2016.09.009
https://doi.org/10.1016/j.neulet.2016.09.009
Autor:
Mauricio P. Cunha, María F. Cano-Abad, Pablo Hernansanz-Agustín, Antonio Martínez-Ruiz, Ricardo Martínez-Murillo, Izaskun Buendia, Elisa Navarro, Maria Dolores Martin-de-Saavedra, Michael R. Duchen, Manuela G. López, Rafael León, Ana J. Moreno-Ortega
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Growing evidence suggests a close relationship between Alzheimer's Disease (AD) and cerebral hypoxia. Astrocytes play a key role in brain homeostasis and disease states, while some of the earliest changes in AD occur in astrocytes. We have therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519381b11b20f6e0ebf67aa0621957ef
http://hdl.handle.net/10261/188479
http://hdl.handle.net/10261/188479
Autor:
Rocío Lajarín-Cuesta, Francisco J. Martínez-Sanz, Cristóbal de los Ríos, María F. Cano-Abad, Ana J. Moreno-Ortega
Publikováno v:
Neuropharmacology. 95:503-510
CALHM1 is a Ca(2+) channel discovered in 2008, which plays a key role in the neuronal electrical activity, among other functions. However, there are no known efficient blockers able to modulate its Ca(2+) handling ability. We herein describe that ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14731caefa28f6d00a80f2ae2c3d63ab
https://doi.org/10.1016/j.neuropharm.2015.02.016
https://doi.org/10.1016/j.neuropharm.2015.02.016
Autor:
María Dolores, Martin-de-Saavedra, Elisa, Navarro, Ana J, Moreno-Ortega, Mauricio P, Cunha, Izaskun, Buendia, Pablo, Hernansanz-Agustín, Rafael, León, María F, Cano-Abad, Antonio, Martínez-Ruiz, Ricardo, Martínez-Murillo, Michael R, Duchen, Manuela G, López
Publikováno v:
Journal of neurochemistry. 145(2)
Growing evidence suggests a close relationship between Alzheimer's Disease (AD) and cerebral hypoxia. Astrocytes play a key role in brain homeostasis and disease states, while some of the earliest changes in AD occur in astrocytes. We have therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe03d8da4c7ee0caab39470a1242d436
https://pubmed.ncbi.nlm.nih.gov/29315575
https://pubmed.ncbi.nlm.nih.gov/29315575
Overcoming Glucocorticoid Resistances and Improving Antitumor Therapies: Lipid and Polymers Carriers
Autor:
Ana J. Moreno-Ortega, María F. Cano-Abad, Cristina Martín-Sabroso, Juan Aparicio-Blanco, Ana Isabel Fraguas-Sánchez, Ana Isabel Torres-Suárez
Publikováno v:
Pharmaceutical Research. 32:968-985
To improve chemotherapy protocols of lymphoid malignancies, by using polymeric and lipid microparticles as controlled delivery systems of dexamethasone, part of all combined chemotherapy protocols for its strong-inducing effect on malignant lymphobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6069a7b2423ab7a8f67b96e685cfccc9
https://doi.org/10.1007/s11095-014-1510-4
https://doi.org/10.1007/s11095-014-1510-4
Autor:
Tatiana M. Domingues, Antonio Miranda, Gioconda E. D. D. Moura, Victor H. C. Ferreira, Edgar J. Paredes-Gamero, Ivarne L.S. Tersariol, Helena B. Nader, Ana J. Moreno-Ortega, Giselle Z. Justo, María F. Cano-Abad, Alice T. Ferreira, Rafael L. Casaes-Rodrigues, Marcus V. Buri, Edvaldo S. Trindade
Publikováno v:
Molecular Pharmaceutics. 9:2686-2697
In recent years, the antitumoral activity of antimicrobial peptides (AMPs) has been the goal of many research studies. Among AMPs, gomesin (Gm) displays antitumor activity by unknown mechanisms. Herein, we studied the cytotoxicity of Gm in the Chines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc0ffed34f633a01548fe3c7b8d9256
https://doi.org/10.1021/mp300251j
https://doi.org/10.1021/mp300251j
Autor:
Juan Milla, Elba Alonso, Ana Ruiz-Nuño, María F. Cano-Abad, Antonio G. García, Mónica S. Montesinos, José David Machado, Ana J. Moreno-Ortega, Ricardo Borges
Publikováno v:
Cell Calcium. 50:332-342
The augmentation of neurotransmitter and hormone release produced by ouabain inhibition of plasmalemmal Na+/K+-ATPase (NKA) is well established. However, the mechanism underlying this action is still controversial. Here we have shown that in bovine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf1829ca60390a2f9eec6b24b3931d5
https://doi.org/10.1016/j.ceca.2011.06.002
https://doi.org/10.1016/j.ceca.2011.06.002
Autor:
Ana Ruiz-Nuño, María F. Cano-Abad, Lamiaa Mouhid Al-achbili, Cristóbal de los Ríos, Antonio G. García, Elba Alonso, Ana J. Moreno-Ortega
Publikováno v:
Neurotoxicity research. 30(3)
Alternatives for the treatment of amyotrophic lateral sclerosis (ALS) are scarce and controversial. The etiology of neuronal vulnerability in ALS is being studied in motor neuron-like NSC-34 cells to determine the underlying mechanisms leading to sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181b0caa0da02b96efeef57ab36df21b
https://pubmed.ncbi.nlm.nih.gov/27126806
https://pubmed.ncbi.nlm.nih.gov/27126806
Autor:
Raquel López-Arribas, Francisco J. Martínez-Sanz, Cristóbal de los Ríos, María F. Cano-Abad, José C. Fernández-Morales, Laura González-Lafuente, Rocío Lajarín-Cuesta, Ana J. Moreno-Ortega
Publikováno v:
ACS chemical neuroscience. 6(9)
Mitochondria regulate cellular Ca(2+) oscillations, taking up Ca(2+) through its uniporter and releasing it through the mitochondrial sodium/calcium exchanger. The role of mitochondria in the regulation of Ca(2+) cycle has received much attention rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45130b1e8753cbd6654b17b975bbc13
https://pubmed.ncbi.nlm.nih.gov/26192029
https://pubmed.ncbi.nlm.nih.gov/26192029
Autor:
Javier Egea, Lamia Mouhid, Ana J. Moreno-Ortega, Manuela G. López, Susana Lucea, Izaskun Buendia, Ana Ruiz-Nuño, María F. Cano-Abad
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
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Aging Cell
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Aging Cell
The mutated form of the Ca2+ channel CALHM1 (Ca2+ homeostasis modulator 1), P86L-CALHM1, has been correlated with early onset of Alzheimer’s disease (AD). P86L-CALHM1 increases production of amyloid beta (Ab) upon extracellular Ca2+ removal and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7267996589ee5fb613199141ac30861
http://hdl.handle.net/10486/671438
http://hdl.handle.net/10486/671438