Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ana Ivonne Vazquez-Armendariz"'
Autor:
Learta Pervizaj-Oruqaj, Balachandar Selvakumar, Maximiliano Ruben Ferrero, Monika Heiner, Christina Malainou, Rolf David Glaser, Jochen Wilhelm, Marek Bartkuhn, Astrid Weiss, Ioannis Alexopoulos, Biruta Witte, Stefan Gattenlöhner, István Vadász, Rory Edward Morty, Werner Seeger, Ralph Theo Schermuly, Ana Ivonne Vazquez-Armendariz, Susanne Herold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Influenza A virus (IAV) infection mobilizes bone marrow-derived macrophages (BMDM) that gradually undergo transition to tissue-resident alveolar macrophages (TR-AM) in the inflamed lung. Combining high-dimensional single-cell transcriptomics
Externí odkaz:
https://doaj.org/article/78b9668d870244cca6b2f62d7f2fe96b
Autor:
Andreas Hoek, Katharina Maibach, Ebru Özmen, Ana Ivonne Vazquez-Armendariz, Jan Philipp Mengel, Torsten Hain, Susanne Herold, Alexander Goesmann
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background The technology of single cell RNA sequencing (scRNA-seq) has gained massively in popularity as it allows unprecedented insights into cellular heterogeneity as well as identification and characterization of (sub-)cellular populatio
Externí odkaz:
https://doaj.org/article/3db7ce05a2554d5ca2c5575561f26aa1
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100594- (2021)
Summary: Organoid models have been shown to be valuable tools for studying epithelial-mesenchymal crosstalk during biological and pathological settings. Our data identified ACTA2+ PDGFRα+ repair-supportive mesenchymal cells as an important component
Externí odkaz:
https://doaj.org/article/4cf53fbb77f54261ab30637c3b495cbd
Autor:
Vahid Kheirollahi, Roxana M. Wasnick, Valentina Biasin, Ana Ivonne Vazquez-Armendariz, Xuran Chu, Alena Moiseenko, Astrid Weiss, Jochen Wilhelm, Jin-San Zhang, Grazyna Kwapiszewska, Susanne Herold, Ralph T. Schermuly, Bernard Mari, Xiaokun Li, Werner Seeger, Andreas Günther, Saverio Bellusci, Elie El Agha
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Idiopathic pulmonary fibrosis is associated with myofibroblast activation in the lungs and metabolic alterations. Here, the authors show that the antidiabetic drug metformin has antifibrotic effects in human-derived samples and mouse models, by modul
Externí odkaz:
https://doaj.org/article/8abd0f7510244108a605662c2e07b3a9
Autor:
Vahid Kheirollahi, Ali Khadim, Georgios Kiliaris, Martina Korfei, Margarida Maria Barroso, Ioannis Alexopoulos, Ana Ivonne Vazquez-Armendariz, Malgorzata Wygrecka, Clemens Ruppert, Andreas Guenther, Werner Seeger, Susanne Herold, Elie El Agha
Publikováno v:
Cells, Vol 11, Iss 12, p 1973 (2022)
Insulin-like growth factor (IGF) signaling controls the development and growth of many organs, including the lung. Loss of function of Igf1 or its receptor Igf1r impairs lung development and leads to neonatal respiratory distress in mice. Although ma
Externí odkaz:
https://doaj.org/article/344e6162dafe47c989dbf8231cb7f25c
Autor:
Xuran Chu, Sara Taghizadeh, Ana Ivonne Vazquez-Armendariz, Susanne Herold, Lei Chong, Chengshui Chen, Jin-San Zhang, Elie El Agha, Saverio Bellusci
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Fgf10 is a key gene during development, homeostasis and repair after injury. We previously reported a knock-in Fgf10Cre–ERT2 line (with the Cre-ERT2 cassette inserted in frame with the start codon of exon 1), called thereafter Fgf10Ki–v1, to targ
Externí odkaz:
https://doaj.org/article/df25cc732fa745699ef4ad1246a250d5
From Clones to Buds and Branches: The Use of Lung Organoids to Model Branching Morphogenesis Ex Vivo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Three-dimensional (3D) organoid culture systems have rapidly emerged as powerful tools to study organ development and disease. The lung is a complex and highly specialized organ that comprises more than 40 cell types that offer several region-specifi
Externí odkaz:
https://doaj.org/article/3212ae7425104a41a5eebd0db81bf0aa
Publikováno v:
Cells, Vol 11, Iss 9, p 1526 (2022)
Idiopathic pulmonary fibrosis (IPF) is a progressive and often lethal interstitial lung disease of unknown aetiology. IPF is characterised by myofibroblast activation, tissue stiffening, and alveolar epithelium injury. As current IPF treatments fail
Externí odkaz:
https://doaj.org/article/635a051d4ae541f48e0e7ae2dc80257b
Autor:
Matthew R. Jones, Arun Lingampally, Jin Wu, Jamschid Sedighi, Negah Ahmadvand, Jochen Wilhelm, Ana Ivonne Vazquez-Armendariz, Susanne Herold, Chengshui Chen, Jin-San Zhang, Saverio Bellusci, Cho-Ming Chao
Publikováno v:
Cells, Vol 9, Iss 5, p 1274 (2020)
Branching morphogenesis is the basic developmental mode common to organs such as the lungs that undergo a process of ramification from a rudimentary tree. However, the precise molecular and cellular bases underlying the formation of branching organs
Externí odkaz:
https://doaj.org/article/dc7304fc9fa7456dafd499f29f91d501
Autor:
Matthew R. Jones, Arun Lingampally, Negah Ahmadvand, Lei Chong, Jin Wu, Jochen Wilhem, Ana Ivonne Vazquez-Armendariz, Meshal Ansari, Susanne Herold, David M. Ornitz, Herbert B. Schiller, Cho-Ming Chao, Jin-San Zhang, Gianni Carraro, Saverio Bellusci
Publikováno v:
Cell. Mol. Life Sci. 79:609 (2022)
The specification, characterization, and fate of alveolar type 1 and type 2 (AT1 and AT2) progenitors during embryonic lung development are poorly defined. Current models of distal epithelial lineage formation fail to capture the heterogeneity and dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb8d3937ad4d2ab7484bd4a2ee334cf
https://doi.org/10.1007/s00018-022-04626-2
https://doi.org/10.1007/s00018-022-04626-2