Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Ana Isabel, Tomaz"'
Autor:
Andres Alguacil, Franco Scalambra, Antonio Romerosa, Andreia Bento-Oliveira, Fernanda Marques, Ines Maximiano, Rodrigo F. M. de Almeida, Ana Isabel Tomaz, Andreia Valente
Publikováno v:
Bioinorganic Chemistry and Applications, Vol 2023 (2023)
Piano-stool-{CpRu} complexes containing 1,3,5-triaza-7-phosphaadamantane (PTA), N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA), and 3,7-dimethyl-1,3,7-triaza-5-phosphabyciclo[3.3.1]nonane (dmoPTA) were evaluated as drugs against breast cancer. The
Externí odkaz:
https://doaj.org/article/a1c975689b5b4067aa0e703787d31530
Autor:
Radoslaw Starosta, Telma C. Santos, Andreia F. Dinis de Sousa, Maria Soledade Santos, M. Luisa Corvo, Ana Isabel Tomaz, Rodrigo F. M. de Almeida
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
This work addresses the possible role of the cell membrane in the molecular mechanism of action of two salan-type ruthenium complexes that were previously shown to be active against human tumor cells, namely [Ru(III)(L1)(PPh3)Cl] and [Ru(III)(L2)(PPh
Externí odkaz:
https://doaj.org/article/f8b599beb5e3471fb41b40f9ecc04dd6
Autor:
Cristina P. Matos, Zelal Adiguzel, Yasemin Yildizhan, Buse Cevatemre, Tugba Bagci-Onder, Ozge Cevik, Patrique Nunes, Liliana P. Ferreira, Maria Deus Carvalho, Débora L. Campos, Fernando R. Pavan, João Costa Pessoa, Maria Helena Garcia, Ana Isabel Tomaz, Isabel Correia, Ceyda Acilan
Publikováno v:
Data in Brief, Vol 27, Iss , Pp - (2019)
This dataset is related to the research article entitled “May iron(III) complexes containing phenanthroline derivatives as ligands be prospective anticancer agents?” [1]. It includes the characterization by UV–Vis absorption spectroscopy and ma
Externí odkaz:
https://doaj.org/article/e0d9b64130714e15ab88015c47a1b626
Autor:
Alessia Stefanelli, Ricardo G. Teixeira, Adhan Pilon, Rebecca Warmers, Ingo Ott, Christian R. Kowol, Anamaria Brozovic, Ana Isabel Tomaz, Andreia Valente, Petra Heffeter
Publikováno v:
Cancer Research. 83:4905-4905
Background: Platinum-based anticancer drugs (e.g. Carboplatin and Oxaliplatin) are frequently applied in chemotherapy regimens against several types of cancer including ovarian carcinoma (OC) and colorectal carcinoma (CRC). However, intrinsic or acqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b01e23dcef8595c1c775d02128e54286
https://doi.org/10.1158/1538-7445.am2023-4905
https://doi.org/10.1158/1538-7445.am2023-4905
Autor:
Orsolya Dömötör, Ricardo G. Teixeira, Gabriella Spengler, Fernando Avecilla, Fernanda Marques, Oscar A. Lenis-Rojas, Cristina P. Matos, Rodrigo F.M. de Almeida, Éva A. Enyedy, Ana Isabel Tomaz
Publikováno v:
Journal of inorganic biochemistry. 238
With the aim to incorporate pharmacophore motifs into the Ru(II)-polypyridyl framework, compounds [Ru(II)(1,10-phenantroline)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f15de778ea7cb1ff33ff90864a463fb
https://pubmed.ncbi.nlm.nih.gov/36375357
https://pubmed.ncbi.nlm.nih.gov/36375357
Autor:
Bruno Demoro, Andreia Bento-Oliveira, Fernanda Marques, João Costa Pessoa, Lucía Otero, Dinorah Gambino, Rodrigo F. M. de Almeida, Ana Isabel Tomaz
Publikováno v:
Molecules, Vol 24, Iss 16, p 2861 (2019)
The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite appealing in cancer chemotherapy. This work examined the anticancer activity of an anti-trypa
Externí odkaz:
https://doaj.org/article/da223ba3fd6943a8ba9e673bda17a441
Autor:
Valeria Ferretti, Cristina P. Matos, Catarina Canelas, João Costa Pessoa, Ana Isabel Tomaz, Radosław Starosta, Isabel Correia, Ignacio E. León
Publikováno v:
Journal of inorganic biochemistry. 236
Due to the growing prevalence of cancer diseases, new therapeutic options are urgently needed, and drugs based on metal ions other than platinum are alternatives with exciting possibilities. We report the synthesis, characterization and biological ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a871f4ee400ee73c729d96be38e32d82
https://pubmed.ncbi.nlm.nih.gov/36049258
https://pubmed.ncbi.nlm.nih.gov/36049258
Autor:
Cristina P. Matos, Melissa Albino, Joana Lopes, Ana Silveira Viana, Leonor Côrte-Real, Filipa Mendes, João Costa Pessoa, Ana Isabel Tomaz, Catarina Pinto Reis, Maria Manuela Gaspar, Isabel Correia
Publikováno v:
International journal of pharmaceutics. 623
Malignant melanoma is an aggressive and deadly form of skin cancer and novel and improved therapeutic options are needed. A promising strategy involves the use of metallodrugs combined with liposomes for targeted delivery to cancer cells. In this wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae23e5b41af21885c22a098b48d0e695
https://pubmed.ncbi.nlm.nih.gov/35718249
https://pubmed.ncbi.nlm.nih.gov/35718249
Autor:
Ricardo G. Teixeira, Alessia Stefanelli, Adhan Pilon, Rebecca Warmers, Xavier Fontrodona, Isabel Romero, Ana Isabel Tomaz, Anamaria Brozovic, Petra Heffeter, Andreia Valente
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d557b9db64fdf683fdffa7ba6bde9b34
https://doi.org/10.3390/ecmc2021-11532
https://doi.org/10.3390/ecmc2021-11532
Autor:
Fernanda Marques, Lurdes Gano, Ana Isabel Tomaz, Francisco Tortosa, Tânia S. Morais, A. P. Alves de Matos, Andreia Valente, Teresa Pinheiro, Marta Martins, Tiago F. Jorge, Maria L. S. Gonçalves, Maria Helena Garcia
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 19:1262-1275
Background:Ruthenium complexes have been extensively investigated for their prospective value as alternatives to cisplatin. Recently, we reported the in vitro anticancer properties of a family of organometallic ruthenium( II)-cyclopentadienyl complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d888ffed79b4254d3d102a62b776e78
https://doi.org/10.2174/1871520619666190318152726
https://doi.org/10.2174/1871520619666190318152726