Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ana Innerárity"'
Autor:
Ana Innerárity, Angel Pazos, Elena del Olmo, Luis Labeaga, Inés Artaiz, Aurelio Orjales, Arturo Zazpe, Elena Castro
Publikováno v:
Neuropharmacology. 51:129-140
In order to better define the role of 5-HT(1A) receptors in the modulation of extrapyramidal motor functions, we investigated the effect of 5-HT(1A) agonists on tacrine-induced tremulous jaw movements (TJM) in rats, a putative model of parkinsonian t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d09cd56e94aa17a46083b27c3e1d584
https://doi.org/10.1016/j.neuropharm.2006.03.008
https://doi.org/10.1016/j.neuropharm.2006.03.008
Publikováno v:
Drugs in R & D. 7:219-231
Objective: We set out to establish the in vivo histamine H1 receptor antagonistic (antihistaminic) and antiallergic properties of bilastine. Methods: In vivo antihistaminic activity experiments consisted of measurement of: inhibition of increase in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bbb9bc7e64f2ad670b71619c5d1ffa
https://doi.org/10.2165/00126839-200607040-00002
https://doi.org/10.2165/00126839-200607040-00002
Autor:
Luis Labeaga, Ana Innerárity, Elena Castro, Ruth Pena, Arturo Zazpe, Angel Pazos, Álvaro Díaz, Inés Artaiz, Aurelio Orjales, José Ángel Ruiz-Ortega, Elena del Olmo
Publikováno v:
Psychopharmacology. 182:400-413
Serotonin (5-HT) and norepinephrine (NE) re-uptake inhibitors (SNRIs) have been proposed to have a higher efficacy and/or faster onset of action than previously available antidepressants.We examined in biochemical, electrophysiological and behavioura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b273616da177e2f24726f340626fa2
https://doi.org/10.1007/s00213-005-0087-3
https://doi.org/10.1007/s00213-005-0087-3
Publikováno v:
Drugs in R & D. 6:371-384
Objective: This study aimed to establish the receptor selectivity and antihistaminic activity of bilastine, a new selective antihistamine receptor antagonist. Design and methods: In vitro experiments were conducted using a receptor binding screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68adddf3ed3d7657c75360d5735ea07f
https://doi.org/10.2165/00126839-200506060-00005
https://doi.org/10.2165/00126839-200506060-00005
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:189-192
A series of 4-amino-5-chloro-2-methoxybenzoates and benzamides containing the 5- and 6-isoquinuclidinyl system was synthesised and evaluated for binding to 5-HT 3 , 5-HT 4 and D 2 receptors. In general, the isoquinuclidine derivatives at the 5-positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeccc6688886d4f909b2b4cb4dcca1c
https://doi.org/10.1016/s0960-894x(01)00693-x
https://doi.org/10.1016/s0960-894x(01)00693-x
Autor:
Ana Innerárity, Luis Labeaga, J. C. Gil‐Sanchez, R. Corcostegui, A. Berisa, Ramón Mosquera, L. Alonso‐Cires, M. Ucelay, Aurelio Orjales
Publikováno v:
European Journal of Medicinal Chemistry. 31:813-818
New 4-(diphenylmethyl)-1-piperazine derivatives with a terminal heteroaryl or cycloalkyl amide fragment were synthesized and evaluated for their antihistaminic, anticholinergic and antiallergic activities. Tested compounds were found to be moderate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ca1d430705935311dc5550337a47a6
https://doi.org/10.1016/0223-5234(96)83975-4
https://doi.org/10.1016/0223-5234(96)83975-4
Publikováno v:
European Journal of Medicinal Chemistry. 30:651-654
Summary New 4-amino-5-chloro-2-methoxybenzamide derivatives 4 with antagonist activity at the 5-HT 4 receptor are reported. They exhibit good selectivity for the 5-HT 4 receptor over the D 2 and 5-HT 3 receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d93590167773d0f36acb1a1350e0793
https://doi.org/10.1016/0223-5234(96)88282-1
https://doi.org/10.1016/0223-5234(96)88282-1
Publikováno v:
ChemInform. 26
Summary New 4-amino-5-chloro-2-methoxybenzamide derivatives 4 with antagonist activity at the 5-HT 4 receptor are reported. They exhibit good selectivity for the 5-HT 4 receptor over the D 2 and 5-HT 3 receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc7a4d17af02a680fc0a56b38a9ef13b
https://doi.org/10.1002/chin.199548106
https://doi.org/10.1002/chin.199548106
Autor:
Ana Innerárity, Luis Labeaga, M. Ucelay, R. Corcostegui, Aurelio Orjales, A. Berisa, J. C. Gil‐Sanchez, L. Alonso‐Cires, Ramón Mosquera
Publikováno v:
ChemInform. 28
New 4-(diphenylmethyl)-1-piperazine derivatives with a terminal heteroaryl or cycloalkyl amide fragment were synthesized and evaluated for their antihistaminic, anticholinergic and antiallergic activities. Tested compounds were found to be moderate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be7b10db600a8b1bc35d83fd600f9e09
https://doi.org/10.1002/chin.199708233
https://doi.org/10.1002/chin.199708233
Publikováno v:
ChemInform. 33
A series of 4-amino-5-chloro-2-methoxybenzoates and benzamides containing the 5- and 6-isoquinuclidinyl system was synthesised and evaluated for binding to 5-HT 3 , 5-HT 4 and D 2 receptors. In general, the isoquinuclidine derivatives at the 5-positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6b7518f0b0bcbc1156d2e6777ebe46
https://doi.org/10.1002/chin.200219141
https://doi.org/10.1002/chin.200219141