Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ana I. Matos"'
Autor:
Ana I. Matos, Carina Peres, Barbara Carreira, Liane I. F. Moura, Rita C. Acúrcio, Theresa Vogel, Erik Wegener, Filipa Ribeiro, Marta B. Afonso, Fábio M. F. Santos, Águeda Martínez‐Barriocanal, Diego Arango, Ana S. Viana, Pedro M. P. Góis, Liana C. Silva, Cecília M. P. Rodrigues, Luis Graca, Rainer Jordan, Ronit Satchi‐Fainaro, Helena F. Florindo
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Immune checkpoint blockade reaches remarkable clinical responses. However, even in the most favorable cases, half of these patients do not benefit from these therapies in the long term. It is hypothesized that the activation of host immunity
Externí odkaz:
https://doaj.org/article/4b20ef243e294bf990270de291c0adb7
Autor:
David Pires, Manoj Mandal, Ana I. Matos, Carina Peres, Maria João Catalão, José Miguel Azevedo-Pereira, Ronit Satchi-Fainaro, Helena F. Florindo, Elsa Anes
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 729 (2023)
The golden age of antibiotics for tuberculosis (TB) is marked by its success in the 1950s of the last century. However, TB is not under control, and the rise in antibiotic resistance worldwide is a major threat to global health care. Understanding th
Externí odkaz:
https://doaj.org/article/fd4ab8f8cb614e7bbe58b5d7533af708
Autor:
Barbara Carreira, Rita A. Acúrcio, Sabina Pozzi, Ron Kleiner, Liane I. Moura, Ana I. Matos, Daniela vaskovich, Carina Peres, Adelaide Fernandes, Sara Xapelli, Ronit Satchi-Fainaro, Helena F. Florindo
Publikováno v:
Cancer Research. 83:835-835
Sixty percent of melanoma patients present brain metastases, having low response rates to current systemic therapies, which do not prolong survival. New therapeutic options to address this clinical need are urgent. Here, we report the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edff0e471b62de015878db1b3c507d4e
https://doi.org/10.1158/1538-7445.am2023-835
https://doi.org/10.1158/1538-7445.am2023-835
Autor:
Carina Peres, Ana I. Matos, Neta Erez, Helena F. Florindo, Hila Doron, Sabina Pozzi, Eva Zupancic, João Conniot, Ana S. Viana, Pedro M. P. Gois, Liane I.F. Moura, Anna Scomparin, Steffen Jung, Ronit Satchi-Fainaro, Ron Kleiner, Eilam Yeini
Publikováno v:
Nature Nanotechnology. 14:891-901
A low response rate, acquired resistance and severe side effects have limited the clinical outcomes of immune checkpoint therapy. Here, we show that combining cancer nanovaccines with an anti-PD-1 antibody (αPD-1) for immunosuppression blockade and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af9ca2f830640d064f4e847823d6e93
https://doi.org/10.1038/s41565-019-0512-0
https://doi.org/10.1038/s41565-019-0512-0
Autor:
Rita C. Acúrcio, Helena F. Florindo, Carina Peres, Barbara Carreira, Daniella Vaskovich-Koubi, Sabina Pozzi, Ronit Satchi-Fainaro, Ana I. Matos, Liane I.F. Moura, Ron Kleiner
Publikováno v:
Advanced drug delivery reviews. 172
The remarkable success of targeted immunotherapies is revolutionizing cancer treatment. However, tumor heterogeneity and low immunogenicity, in addition to several tumor-associated immunosuppression mechanisms are among the major factors that have pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8881d13a21f0b23da1bc31fc623e27b1
https://pubmed.ncbi.nlm.nih.gov/33711401
https://pubmed.ncbi.nlm.nih.gov/33711401
Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation
Autor:
Barbara Carreira, Liane I.F. Moura, Helena F. Florindo, Anna Scomparin, Véronique Préat, Ronit Satchi-Fainaro, Carina Peres, Vanessa Sainz, Ana Luisa Silva, João Conniot, Ana I. Matos
Publikováno v:
Seminars in Immunology. 34:3-24
Nanotechnology-based strategies can dramatically impact the treatment, prevention and diagnosis of a wide range of diseases. Despite the unprecedented success achieved with the use of nanomaterials to address unmet biomedical needs and their particul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d21f5ab729a371b4b3b62d257c3614
https://doi.org/10.1016/j.smim.2017.09.003
https://doi.org/10.1016/j.smim.2017.09.003
Autor:
Luis F. Veiros, João Gonçalves, Helena F. Florindo, Fábio M. F. Santos, Ana I. Matos, Pedro M. P. Gois, Ana E. Ventura
Publikováno v:
Angewandte Chemie. 129:9474-9478
Herein is described a new modular platform for the construction of cancer-cell-targeting drug conjugates. Tripodal boronate complexes featuring reversible covalent bonds were designed to accommodate a cytotoxic drug (bortezomib), poly(ethylene glycol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a46865d5c216ba7a8b76e96dc09ffb
https://doi.org/10.1002/ange.201703492
https://doi.org/10.1002/ange.201703492
Autor:
Ana I. Matos, Águeda Martínez-Barriocanal, Barbara Carreira, Liane I.F. Moura, João Conniot, Carina Peres, Véronique Préat, Diego Arango, Helena F. Florindo, João Pedro Conde, Anna Scomparin, Ronit Satchi-Fainaro, Thibaut Fourniols
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society, (2019)
Colorectal cancer (CRC) is among the five most commonly diagnosed cancers worldwide, constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third and second most frequent cancer in men and women worldwide, accounting f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7463c69cce2154d516679d84f0f787ab
http://hdl.handle.net/2318/1718921
http://hdl.handle.net/2318/1718921
Autor:
Liane I.F. Moura, Alessio Malfanti, Elise Guégain, Ana I. Matos, María J. Vicent, Helena F. Florindo, Carina Peres, Vanessa Sainz, Mire Zloh
Publikováno v:
Materials Horizons
Well-defined synthetic branched nanostructures form an emerging subclass of macromolecular structures, whose 3D structure and multivalency offer unique opportunities for fine-tuning their internalization and cellular targeting. In particular, dendrim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cc635885c9fffe75f7ac69db060b03
Autor:
Daniella Vaskovich-Koubi, Sabina Pozzi, Barbara Carreira, Helena F. Florindo, Carina Peres, Ron Kleiner, Ronit Satchi-Fainaro, Mariana Bento, Ana I. Matos, Rita C. Acúrcio
Publikováno v:
Advanced Therapeutics. 4:2000147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e358e99091f05277f87b4db2fb988e
https://doi.org/10.1002/adtp.202000147
https://doi.org/10.1002/adtp.202000147