Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Ana I Vazquez"'
Autor:
Gustavo de Los Campos, Torsten Pook, Agustin Gonzalez-Reymundez, Henner Simianer, George Mias, Ana I Vazquez
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243251 (2020)
Modern genomic data sets often involve multiple data-layers (e.g., DNA-sequence, gene expression), each of which itself can be high-dimensional. The biological processes underlying these data-layers can lead to intricate multivariate association patt
Externí odkaz:
https://doaj.org/article/7261cfea6eeb49368364cdfde6d2517f
Autor:
Jennifer Quantius, Carole Schmoldt, Ana I Vazquez-Armendariz, Christin Becker, Elie El Agha, Jochen Wilhelm, Rory E Morty, István Vadász, Konstantin Mayer, Stefan Gattenloehner, Ludger Fink, Mikhail Matrosovich, Xiaokun Li, Werner Seeger, Juergen Lohmeyer, Saverio Bellusci, Susanne Herold
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005544 (2016)
Influenza Virus (IV) pneumonia is associated with severe damage of the lung epithelium and respiratory failure. Apart from efficient host defense, structural repair of the injured epithelium is crucial for survival of severe pneumonia. The molecular
Externí odkaz:
https://doaj.org/article/2bfa5c69e1f5438eb45ed4d593fc7dab
Autor:
Ana I Vazquez, Yann C Klimentidis, Emily J Dhurandhar, Yogasudha C Veturi, Paulino Paérez-Rodríguez
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123818 (2015)
Lifestyle and genetic factors play a large role in the development of Type 2 Diabetes (T2D). Despite the important role of genetic factors, genetic information is not incorporated into the clinical assessment of T2D risk. We assessed and compared Who
Externí odkaz:
https://doaj.org/article/f9f6f2d7053e4593a6af7bc253b4c454
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Whole Genome Prediction (WGP) jointly fits thousands of SNPs into a regression model to yield estimates for the contribution of markers to the overall variance of a particular trait, and for their associations with that trait. To date, WGP has offere
Externí odkaz:
https://doaj.org/article/949e92e123404fd0b9dc8aa1b7683b55
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003608 (2013)
Despite important advances from Genome Wide Association Studies (GWAS), for most complex human traits and diseases, a sizable proportion of genetic variance remains unexplained and prediction accuracy (PA) is usually low. Evidence suggests that PA ca
Externí odkaz:
https://doaj.org/article/bbe1a25bf5904abaa47ce9c378b0fddd
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
The impact of extent of genetic relatedness on accuracy of genome-enabled predictions was assessed using a dairy cattle population and alternative cross-validation (CV) strategies were compared. The CV layouts consisted of training and testing sets o
Externí odkaz:
https://doaj.org/article/9715c1a75fd94c96b9a395785f3fddc3
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40964 (2012)
Genetic factors are believed to account for 25% of the interindividual differences in Years of Life (YL) among humans. However, the genetic loci that have thus far been found to be associated with YL explain a very small proportion of the expected ge
Externí odkaz:
https://doaj.org/article/6ab9c33fca72475b97c4f3a81119f3b9
Autor:
Robert Makowsky, Nicholas M Pajewski, Yann C Klimentidis, Ana I Vazquez, Christine W Duarte, David B Allison, Gustavo de los Campos
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1002051 (2011)
Despite rapid advances in genomic technology, our ability to account for phenotypic variation using genetic information remains limited for many traits. This has unfortunately resulted in limited application of genetic data towards preventive and per
Externí odkaz:
https://doaj.org/article/1b382d47e3d14ee9a79db4b48e6cc84d
Autor:
Mahsa Zabihi, Ali Khadim, Theresa M. Schäfer, Ioannis Alexopoulos, Marek Bartkuhn, Elie El Agha, Ana I. Vazquez-Armendariz, Susanne Herold
Publikováno v:
Cells, Vol 13, Iss 11, p 922 (2024)
Organoid models have become an integral part of the research methodology in the lung field. These systems allow for the study of progenitor and stem cell self-renewal, self-organization, and differentiation. Distinct models of lung organoids mimickin
Externí odkaz:
https://doaj.org/article/6f48790f13f74164b8e8b5b978d3c2e3
Autor:
Mandy S. Hall, Victoria L. Holt, Claudia Holzman, Ana I. Vazquez, Holly R. Harris, Sawsan As-Sanie, Kristen Upson
Publikováno v:
Fertility and Sterility. 119:644-652
To evaluate the association between breastfeeding history, including lifetime exclusive breastfeeding, and adenomyosis risk.We used data from a case-control study designed with two control groups to address the challenge of selecting non-cases for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483501e85b8817bd80ed54edf7cd2a50
https://doi.org/10.1016/j.fertnstert.2022.12.028
https://doi.org/10.1016/j.fertnstert.2022.12.028