Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Ana I Rodriguez-Perez"'
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract The renin-angiotensin system (RAS) was classically considered a circulating hormonal system that regulates blood pressure. However, different tissues and organs, including the brain, have a local paracrine RAS. Mutual regulation between the
Externí odkaz:
https://doaj.org/article/dfa7d084a28d4264b26af20b3308215e
Autor:
Lucia Lage, Ana I. Rodriguez-Perez, Begoña Villar-Cheda, Jose L. Labandeira-Garcia, Antonio Dominguez-Meijide
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract The brain renin-angiotensin system (RAS) has been related to dopaminergic degeneration, and high expression of the angiotensin II (AngII) type 1 receptor (AT1) gene is a marker of the most vulnerable neurons in humans. However, it is unknown
Externí odkaz:
https://doaj.org/article/840cafb5aecd4c9f93c5a414836891d4
Autor:
Carmen M. Labandeira, Maria A. Pedrosa, Aloia Quijano, Rita Valenzuela, Pablo Garrido-Gil, Mariña Sanchez-Andrade, Juan A. Suarez-Quintanilla, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract The role of autoimmunity in neurodegeneration has been increasingly suggested. The renin-angiotensin system (RAS) autoantibodies play a major role in several peripheral inflammatory processes. Dysregulation of brain RAS has been involved in
Externí odkaz:
https://doaj.org/article/f83718c455114c328bfe7464be77c6e6
Autor:
Maria A. Pedrosa, Carmen M. Labandeira, Nerea Lago-Baameiro, Rita Valenzuela, Maria Pardo, Jose Luis Labandeira-Garcia, Ana I. Rodriguez-Perez
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2045 (2023)
Several studies showed an association between metabolic syndrome (MetS) and Parkinson’s disease (PD). The linking mechanisms remain unclear. MetS promotes low-grade peripheral oxidative stress and inflammation and dysregulation of the adipose renin
Externí odkaz:
https://doaj.org/article/dc84c86ce0974d858f7c8460bce42ec4
Autor:
Carmen M Labandeira, Arturo Fraga-Bau, David Arias Ron, Elena Alvarez-Rodriguez, Pablo Vicente-Alba, Javier Lago-Garma, Ana I Rodriguez-Perez
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 8, Pp 1652-1658 (2022)
In the last decade, attention has become greater to the relationship between neurodegeneration and abnormal insulin signaling in the central nervous system, as insulin in the brain is implicated in neuronal survival, plasticity, oxidative stress and
Externí odkaz:
https://doaj.org/article/ab13aa1958d242638c41be8cc74e1068
Autor:
Rafael Rivas-Santisteban, Ana I. Rodriguez-Perez, Ana Muñoz, Irene Reyes-Resina, José Luis Labandeira-García, Gemma Navarro, Rafael Franco
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background/aims The renin-angiotensin system (RAS) is altered in Parkinson’s disease (PD), a disease due to substantia nigra neurodegeneration and whose dopamine-replacement therapy, using the precursor levodopa, leads to dyskinesias as th
Externí odkaz:
https://doaj.org/article/5b12098c13c3447c81a4afd49f51dce7
Autor:
Rita Valenzuela, Ana I. Rodriguez-Perez, Maria A. Costa-Besada, Rafael Rivas-Santisteban, Pablo Garrido-Gil, Andrea Lopez-Lopez, Gemma Navarro, Jose L. Lanciego, Rafael Franco, Jose L. Labandeira-Garcia
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102078- (2021)
ACE2 plays a pivotal role in the balance between the pro-oxidative pro-inflammatory and the anti-oxidative anti-inflammatory arms of the renin-angiotensin system. Furthermore, ACE2 is the entry receptor for SARS-CoV-2. Clarification of ACE2-related m
Externí odkaz:
https://doaj.org/article/23210ef8205949708f8f783e72da2298
Autor:
Juan A. Parga, Ana I. Rodriguez-Perez, Maria Garcia-Garrote, Jannette Rodriguez-Pallares, Jose L. Labandeira-Garcia
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 934-942 (2018)
This article describes the effect of the oxidative stress inducers Angiotensin II and 6-hydroxydopamine (6-OHDA) on different cell lines. The levels of expression Angiotensin type 1 and type 2 receptors in different dopaminergic cell lines are shown.
Externí odkaz:
https://doaj.org/article/d48a73624b66434386d22aa635389728
Autor:
Rita Valenzuela, Maria A. Pedrosa, Pablo Garrido‐Gil, Carmen M. Labandeira, Gemma Navarro, Rafael Franco, Ana I. Rodriguez‐Perez, Jose L. Labandeira‐Garcia
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 4, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/87a7219b3f1b410fa07ff8b482feed7c
Autor:
Aloia Quijano, Carmen Diaz-Ruiz, Andrea Lopez-Lopez, Begoña Villar-Cheda, Ana Muñoz, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 329 (2022)
The tissue renin–angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson’s disease (PD). We studied the activat
Externí odkaz:
https://doaj.org/article/bba0dc916a3b430fa3412779f6a057a2