Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ana Hermoso"'
Autor:
Samuel Pontes-Quero, Macarena Fernández-Chacón, Wen Luo, Federica Francesca Lunella, Verónica Casquero-Garcia, Irene Garcia-Gonzalez, Ana Hermoso, Susana F. Rocha, Mayank Bansal, Rui Benedito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
High mitogenic stimuli have been suggested to promote endothelial cell proliferation and sprouting during angiogenesis. Here Pontes-Quero et al., by interfering with levels of VEGF and Notch signalling in single endothelial cells in vivo, find that h
Externí odkaz:
https://doaj.org/article/bdd178fe974e4a4f962429db249693cf
Autor:
Samuel Pontes-Quero, Macarena Fernández-Chacón, Wen Luo, Federica Francesca Lunella, Verónica Casquero-Garcia, Irene Garcia-Gonzalez, Ana Hermoso, Susana F. Rocha, Mayank Bansal, Rui Benedito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained errors in Fig. 8. In panel a, the labels ‘VEGF’, ‘Notch’, ‘p21’, and ‘P-ERK’ were inadvertently omitted. This has been corrected in the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/af843f14dfae4edc80c5f1acc1ae6848
Autor:
Bruna Calsina, Richard P. Beckmann, Raquel Torres-Guzmán, Maria Jose Lallena, Joaquín Amat, Alfonso De Dios, Beatriz Alvarez, Ann M. McNulty, Ana Hermoso, Karsten Boehnke, Sean Buchanan, Jian Du, Xueqian Gong, Carmen Baquero
Publikováno v:
Oncotarget
Abemaciclib is an ATP-competitive, reversible kinase inhibitor selective for CDK4 and CDK6 that has shown antitumor activity as a single agent in hormone receptor positive (HR+) metastatic breast cancer in clinical trials. Here, we examined the mecha
Autor:
Wen Luo, Verónica Casquero-Garcia, Macarena Fernández-Chacón, Mayank Bansal, Samuel Pontes-Quero, Federica Francesca Lunella, Ana Hermoso, Rui Benedito, Irene Garcia-Gonzalez, Susana F. Rocha
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained errors in Fig. 8. In panel a, the labels ‘VEGF’, ‘Notch’, ‘p21’, and ‘P-ERK’ were inadvertently omitted. This has been corrected in the PDF and HTML versions of the Article.
Autor:
Susana F. Rocha, Ana Hermoso, Macarena Fernández-Chacón, Mayank Bansal, Verónica Casquero-Garcia, Samuel Pontes-Quero, Rui Benedito, Federica Francesca Lunella, Irene Garcia-Gonzalez, Wen Luo
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Appropriate therapeutic modulation of endothelial proliferation and sprouting is essential for the effective inhibition of angiogenesis in cancer or its induction in cardiovascular disease. The current view is that an increase in growth factor concen
Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis
Autor:
Maria S. Sanchez-Muñoz, Adrian Galiana-Simal, Giovanna Giovinazzo, Verónica Casquero-Garcia, Luis M. Criado-Rodriguez, Ana Hermoso, Wen Luo, Luis Heredia, Samuel Pontes-Quero, Susana F. Rocha, Sergio Del Olmo-Cabrera, Mayank Bansal, Irene Garcia-Gonzalez, Juan Ramón Perea, Iker Rodriguez-Arabaolaza, Macarena Fernández-Chacón, Rui Benedito
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Cell
Repisalud
Instituto de Salud Carlos III (ISCIII)
instname
Cell
Repisalud
Instituto de Salud Carlos III (ISCIII)
Summary Improved methods for manipulating and analyzing gene function have provided a better understanding of how genes work during organ development and disease. Inducible functional genetic mosaics can be extraordinarily useful in the study of biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234292ba6e08aa39c65521a9af3eddef
http://hdl.handle.net/10486/685831
http://hdl.handle.net/10486/685831
Autor:
Carmen López-Fernández, Ana Hermoso, José Luis Fernández, Jaime Gosálvez, Michael E. Kjelland
Publikováno v:
Aquaculture. 433:173-182
Sperm DNA damage is one of the many factors that have been associated with male infertility. However, sperm DNA fragmentation (SDF) assessment has been challenging because protamines render the nuclear chromatin highly compacted. For those fish speci
Autor:
Ana Hermoso, Bruna Calsina, Sean Buchanan, Cecilia Mur, Xueqian Gong, Karsten Boehnke, Carmen Baquero, Joaquín Amat, Richard P. Beckmann, Alfonso De Dios, Raquel Torres, Maria Jose Lallena
Publikováno v:
Cancer Research. 76:2836-2836
Breast cancer is the second most common cancer worldwide after lung cancer. About 70% of breast cancers express estrogen receptor α (ER+) and/or progesterone receptor (PR+), and these biomarkers are indicative of hormone dependence. However up to 50
Autor:
Karsten Boehnke, Juan A. Velasco, Philip W. Iversen, Joaquín Amat, Christoph Reinhard, Bruna Calsina, Sean Buchanan, Christian R. A. Regenbrecht, Ana Hermoso, Raquel Torres, Marie-Laure Yaspo, Richard P. Beckmann, Dirk Schumacher, Hans Lehrach, Alfonso De Dios, Maria Jose Lallena
Publikováno v:
Cancer Research. 76:2829-2829
Proper patient-tailoring strategy and the validation of novel therapeutic targets remain enormous challenges during drug discovery processes. Patient-derived three-dimensional organoid cell culture models possess great potential to associate compound
Abstract 3101: In-vitro characterization of Abemaciclib pharmacology in ER+ breast cancer cell lines
Autor:
Ann M. McNulty, Bruna Calsina, Raquel Torres, Sean Buchanan, Xueqian Gong, Joaquín Amat, Richard P. Beckmann, Maria Jose Lallena, Jian Du, Karsten Boehnke, Ana Hermoso, Alfonso De Dios
Publikováno v:
Cancer Research. 75:3101-3101
Dysregulation of the cell-cycle is a hallmark of cancer and genetic alterations in its regulatory machinery (or checkpoints) occur in most human tumors. The majority these defects are found in genes encoding for proteins regulating G1 phase progressi