Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Ana Heloneida de Araújo Morais"'
Autor:
Yohanna Layssa dos Santos Melo, Ana Carolina Luchiari, Beatriz Silva Lopes, Maria Gabriela Ferreira Rocha Silva, Tatiana dos Santos Pais, João Eduardo Procópio Gama Cortez, Christina da Silva Camillo, Sérgio Adriane Bezerra de Moura, Juliana Kelly da Silva-Maia, Ana Heloneida de Araújo Morais
Publikováno v:
Toxicology Reports, Vol 13, Iss , Pp 101766- (2024)
The trypsin inhibitor isolated from tamarind seeds (TTI) is being investigated for potential applications in the treatment of noncommunicable diseases (NCD), such as hypertension, obesity, and diabetes. This study aimed to assess TTI embryotoxicity a
Externí odkaz:
https://doaj.org/article/718ff58ee6584204a58ced6623ac768e
Autor:
Gerciane Silva de Oliveira, Amanda Maria de Souza Nascimento, Anna Beatriz Santana Luz, Ana Júlia Felipe Camelo Aguiar, Mayara Santa Rosa Lima, Lídia Leonize Rodrigues Matias, Isabel Rodríguez Amado, Thais Souza Passos, Karla Suzane Florentino da Silva Chaves Damasceno, Norberto de Kássio Vieira Monteiro, Susana Margarida Gomes Moreira, Lorenzo Pastrana, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 67-83 (2023)
Bacterial infections have become a global concern, stimulating the growing demand for natural and biologically safe therapeutic agents with antibacterial action. This study was evaluated the genotoxicity of the trypsin inhibitor isolated from tamarin
Externí odkaz:
https://doaj.org/article/880950d548694b1d88eabf1e066f85a4
Autor:
Ana Júlia Felipe Camelo Aguiar, Wendjilla Fortunato de Medeiros, Juliana Kelly da Silva-Maia, Ingrid Wilza Leal Bezerra, Grasiela Piuvezam, Ana Heloneida de Araújo Morais
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9646 (2024)
Bioinformatics has emerged as a valuable tool for screening drugs and understanding their effects. This systematic review aimed to evaluate whether in silico studies using anti-obesity peptides targeting therapeutic pathways for obesity, when subsequ
Externí odkaz:
https://doaj.org/article/bb1261e0f8824c4aa4abb9d78f20817c
Autor:
Isaiane Medeiros, Ana Francisca Teixeira Gomes, Emilly Guedes Oliveira e Silva, Ingrid Wilza Leal Bezerra, Juliana Kelly da Silva Maia, Grasiela Piuvezam, Ana Heloneida de Araújo Morais
Publikováno v:
Nutrients, Vol 16, Iss 15, p 2395 (2024)
Bioinformatics has expedited the screening of new efficient therapeutic agents for diseases such as diabetes mellitus (DM). The objective of this systematic review (SR) was to understand naturally occurring proteins and peptides studied in silico and
Externí odkaz:
https://doaj.org/article/5bcf2584c49c4987951089c7f09b3703
Autor:
Anna Beatriz Santana Luz, Amanda Fernandes de Medeiros, Gidyenne Christine Bandeira Silva de Medeiros, Grasiela Piuvezam, Thaís Souza Passos, Ana Heloneida de Araújo Morais
Publikováno v:
Nutrients, Vol 16, Iss 15, p 2398 (2024)
Bioactive peptides derived from native proteins modulate physiological processes in the metabolic pathways. Given that multiple protocols in the literature mimic the digestion of dietary components, gathering studies that use such models directed at
Externí odkaz:
https://doaj.org/article/c301d714b20247efa614c3aeda0e27aa
Autor:
Amanda Maria de Souza Nascimento, Victor Hugo de Oliveira Segundo, Ana Júlia Felipe Camelo Aguiar, Grasiela Piuvezam, Thaís Souza Passos, Karla Suzanne Florentino da Silva Florentino da Silva Chaves Damasceno, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 749-759 (2022)
This systematic review (SR) aimed to gather studies describing the antibacterial action mechanisms and mode of trypsin inhibitors. The review protocol was registered (PROSPERO: CRD42020189069). Original articles resulting from studies in animal model
Externí odkaz:
https://doaj.org/article/42f450a47c5641bf896d11804c8c1143
Autor:
Anna Beatriz Santana Luz, Amanda Fernandes de Medeiros, Lucas Lima Bezerra, Mayara Santa Rosa Lima, Annemberg Salvino Pereira, Emilly Guedes Oliveira e Silva, Thais Souza Passos, Norberto de Kássio Vieira Monteiro, Ana Heloneida de Araújo Morais
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 8, Pp 104886- (2023)
The study aimed to prospect in silico native and analogous peptides with anti-SARS-CoV-2 potential derived from the trypsin inhibitor purified from tamarind seeds (TTIp). From the most stable theoretical model of TTIp (TTIp 56/287), in silico cleavag
Externí odkaz:
https://doaj.org/article/a4ebe0342f984a5c9fca4f59aca486ab
Autor:
Mychelle Kytchia Rodrigues Nunes Duarte, Lúcia Leite-Lais, Lucymara Fassarella Agnez-Lima, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais
Publikováno v:
Nutrients, Vol 16, Iss 5, p 607 (2024)
Background: Obesity results from interactions between environmental factors, lifestyle, and genetics. In this scenario, nutritional genomics and nutrigenetic tests stand out, with the promise of helping patients avoid or treat obesity. This narrative
Externí odkaz:
https://doaj.org/article/37978a3986f542e29cc1e1fd78030634
Autor:
Amanda Fernandes de Medeiros, Beatriz Blenda Pinheiro de Souza, Lucas Pinheiro Coutinho, Aline Melro Murad, Paula Ivani Medeiros dos Santos, Norberto de Kássio Vieira Monteiro, Elizeu Antunes dos Santos, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 480-490 (2021)
Trypsin inhibitors from tamarind seed have been studied in vitro and in preclinical studies for the treatment of obesity, its complications and associated comorbidities. It is still necessary to fully understand the structure and behaviour of these m
Externí odkaz:
https://doaj.org/article/0e2a7c5b17194f29b89fe15367ca5315
Autor:
Ana Francisca Teixeira Gomes, Wendjilla Fortunato de Medeiros, Gerciane Silva de Oliveira, Isaiane Medeiros, Juliana Kelly da Silva Maia, Ingrid Wilza Leal Bezerra, Grasiela Piuvezam, Ana Heloneida de Araújo Morais
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279039 (2022)
Obesity is a significant risk factor for several chronic non-communicable diseases, being closely related to Diabetes Mellitus. Computer modeling techniques favor the understanding of interaction mechanisms between specific targets and substances of
Externí odkaz:
https://doaj.org/article/f68e08d458ad4f168ce762f599b25b51