Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Ana Heloneida de A. Morais"'
Autor:
Ana Francisca T. Gomes, Wendjilla F. de Medeiros, Lucas L. Bezerra, Anna Beatriz S. Luz, Francisco C. de Sousa Junior, Sancha H. de L. Vale, Elizeu A. dos Santos, Norberto de K. V. Monteiro, Ana Heloneida de A. Morais
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 6, Pp 105780- (2024)
The aim of this study was to prospect in silico peptides derived from a multifunctional protein and assess their interaction with the insulin receptor (IR). The trypsin inhibitor isolated from tamarind seeds (TTI) was obtained through trypsin-sepharo
Externí odkaz:
https://doaj.org/article/1e5f225cb4bd4cb59669135b7d4d1a46
Autor:
Rafael O. de A. Costa, Thaís S. Passos, Eloyse Mikaelly de S. Silva, Nicolle Caroline S. dos Santos, Ana Heloneida de A. Morais
Publikováno v:
Nanomaterials, Vol 13, Iss 7, p 1166 (2023)
The world scenario has undergone a nutritional transition in which some countries have left the reality of malnutrition and now face an epidemic of excess body weight. Researchers have been looking for strategies to reverse this situation. Peptides a
Externí odkaz:
https://doaj.org/article/793edbd9073847739d955c64e110c5df
Autor:
Rafael O. A. Costa, Isaiane Medeiros, Jaluza L. C. De Queiroz, Lídia L. R. Matias, Mayara S. R. Lima, Gerciane S. De Oliveira, Ana Júlia F. C. Aguiar, Izael S. Costa, Eloyse Mikaelly de S. Silva, Nicolle Caroline S. Dos Santos, Thaís S. Passos, Ana Heloneida De A. Morais
Publikováno v:
Foods, Vol 11, Iss 21, p 3526 (2022)
The study aimed to evaluate the nanoparticles (ECW) containing tamarind trypsin inhibitor (TTI) concerning the storage effect under different conditions on antitrypsin activity and the bioactive potential in a preclinical model. ECW was exposed to di
Externí odkaz:
https://doaj.org/article/c99163d0222f4e869843a62184f16d98
Autor:
Gerciane Silva de Oliveira, Amanda Maria de Souza Nascimento, Anna Beatriz Santana Luz, Ana Júlia Felipe Camelo Aguiar, Mayara Santa Rosa Lima, Lídia Leonize Rodrigues Matias, Isabel Rodríguez Amado, Thais Souza Passos, Karla Suzane Florentino da Silva Chaves Damasceno, Norberto de Kássio Vieira Monteiro, Susana Margarida Gomes Moreira, Lorenzo Pastrana, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 67-83 (2023)
Bacterial infections have become a global concern, stimulating the growing demand for natural and biologically safe therapeutic agents with antibacterial action. This study was evaluated the genotoxicity of the trypsin inhibitor isolated from tamarin
Externí odkaz:
https://doaj.org/article/880950d548694b1d88eabf1e066f85a4
Autor:
Mayara Santa Rosa Lima, Vanessa Cristina Oliveira de Lima, Grasiela Piuvezam, Kesley Pablo Morais de Azevedo, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0270749 (2022)
Several studies in animal models of intestinal inflammation have been performed with the aim of understanding the mechanisms of action of anti-inflammatory proteins and peptides that reduce TNF-α. In order to present the best targets, effects and st
Externí odkaz:
https://doaj.org/article/f7d36b3c4c6e4a04a726718cd7c8979c
Autor:
Sara Sayonara da Cruz Nascimento, Jaluza Luana Carvalho de Queiroz, Amanda Fernandes de Medeiros, Ana Clara de França Nunes, Grasiela Piuvezam, Bruna Leal Lima Maciel, Thaís Souza Passos, Ana Heloneida de Araújo Morais
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273942 (2022)
Obesity is characterized by an adipose tissue mass expansion that presents a risk to health, associated with a chronic increase in circulating inflammatory mediators. Anti-inflammatory agents are an obesity alternative treatment. However, the lack of
Externí odkaz:
https://doaj.org/article/b98b2b816e3d40569e670e12c28f8687
Autor:
Vanessa Cristina Oliveira de Lima, Grasiela Piuvezam, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 405-419 (2019)
The increase in non-communicable chronic diseases has aroused interest in the research of adjuvants to the classic forms of treatments. Obesity and metabolic syndrome are the main targets of confrontation because they relate directly to other chronic
Externí odkaz:
https://doaj.org/article/f17056b63db249d1ae9e3d603170d226
Autor:
Amanda Fernandes de Medeiros, Izael de Sousa Costa, Fabiana Maria Coimbra de Carvalho, Sumika Kiyota, Beatriz Blenda Pinheiro de Souza, Daniel Nogoceke Sifuentes, Raphael Paschoal Serquiz, Bruna Leal Lima Maciel, Adriana Ferreira Uchôa, Elizeu Antunes dos Santos, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 334-348 (2018)
A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and le
Externí odkaz:
https://doaj.org/article/bf10a091414d47a9a9f8b24c94232dd2
Autor:
Gerciane Silva de Oliveira, Amanda Maria de Souza Nascimento, Anna Beatriz Santana Luz, Ana Júlia Felipe Camelo Aguiar, Mayara Santa Rosa Lima, Lídia Leonize Rodrigues Matias, Isabel Rodríguez Amado, Thais Souza Passos, Karla Suzane Florentino da Silva Chaves Damasceno, Norberto de Kássio Vieira Monteiro, Susana Margarida Gomes Moreira, Lorenzo Pastrana, Ana Heloneida de Araújo Morais
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 38:67-83
Bacterial infections have become a global concern, stimulating the growing demand for natural and biologically safe therapeutic agents with antibacterial action. This study was evaluated the genotoxicity of the trypsin inhibitor isolated from tamarin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cf330f01f89f0dd4790aded57c23d9
https://doi.org/10.1080/14756366.2022.2134997
https://doi.org/10.1080/14756366.2022.2134997
Autor:
Ana Paula Araújo de Souza, Lorena Maria Araújo Marinheiro Nascimento, Vanessa Cristina Oliveira de Lima, Fabiana Maria Coimbra de Carvalho, Elizeu Antunes dos Santos, Ana Heloneida de Araújo Morais
Publikováno v:
Demetra, Vol 12, Iss 1, Pp 319-331 (2017)
Objetivo: Este estudo objetiva detectar a atividade antitríptica em semente e farinha comerciais de chia e isolar um inibidor de tripsina presente na semente. Metodologia: Foram realizados extração de proteínas, fracionamento com sulfato de amôn
Externí odkaz:
https://doaj.org/article/8c89ca829dec4af9b9b2d5134a109a32