Výsledky vyhledávání - "Ana Guzman-Aranguez"

Akademický článek

Proteomics Analyses of Small Extracellular Vesicles of Aqueous Humor: Identification and Validation of GAS6 and SPP1 as Glaucoma Markers

Autor: Raquel Rejas-González, Ana Montero-Calle, Alejandro Valverde, Natalia Pastora Salvador, María José Crespo Carballés, Emma Ausín-González, Juan Sánchez-Naves, Susana Campuzano, Rodrigo Barderas, Ana Guzman-Aranguez

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 13, p 6995 (2024)

Cataracts and glaucoma account for a high percentage of vision loss and blindness worldwide. Small extracellular vesicles (sEVs) are released into different body fluids, including the eye’s aqueous humor. Information about their proteome content an

Externí odkaz: https://doaj.org/article/c2227f84328c41f2b7d8e0067e41f1c1

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Akademický článek

Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens from Exosomes Released by CRC Cells and Tissue Samples Showed High Diagnostic Ability for Colorectal Cancer

Publikováno v: Engineering, Vol 7, Iss 10, Pp 1393-1412 (2021)

Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. The five-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stages but lower than 10% w

Externí odkaz: https://doaj.org/article/37d8fc52650e413c80d384b5a7c4075f

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Akademický článek

Beta2 adrenergic receptor silencing change intraocular pressure in New Zealand rabbits

Autor: Patricia Loma, Ana Guzman-Aranguez, Maria J. Perez de Lara, Jesus Pintor

Publikováno v: Journal of Optometry, Vol 11, Iss 2, Pp 69-74 (2018)

Purpose/aim: Glaucoma consists of a group of progressive optic neuropathies that are characterized by degeneration of the optic nerve and irreversible visual filed loss. Elevated intraocular pressure is the only proven treatable risk factor and comme

Externí odkaz: https://doaj.org/article/e7c67182cc7c4293bde39f874db59a5d

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Akademický článek

Safety data on in situ gelling bimatoprost loaded nanovesicular formulations

Autor: Monika Yadav, Ana Guzman-Aranguez, Maria J. Perez de Lara, Mandeep Singh, Joga Singh, Indu Pal Kaur

Publikováno v: Data in Brief, Vol 25, Iss , Pp - (2019)

In vitro cytotoxicity and in vivo acute and 7 days repeat-dose ocular toxicity studies, were conducted in rabbits, in accordance with the Organisation for Economic Co-operation and Development (OECD) guidelines, for bimatoprost loaded nanovesicular a

Externí odkaz: https://doaj.org/article/8b58d4b42e3a44e8a0aa8b9738083234

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Akademický článek

In vitro and in vivo delivery of the secretagogue diadenosine tetraphosphate from conventional and silicone hydrogel soft contact lenses

Autor: Carmen Olalla Dominguez-Godinez, Alba Martin-Gil, Gonzalo Carracedo, Ana Guzman-Aranguez, José Manuel González-Méijome, Jesús Pintor

Publikováno v: Journal of Optometry, Vol 6, Iss 4, Pp 205-211 (2013)

Purpose: To evaluate the possible use of soft contact lenses (CL) to improve the secretagogue role of diadenosine tetraphosphate (Ap4A) promoting tear secretion. Methods: Two conventional hydrogel CL (Omafilcon A and Ocufilcon D) and two silicone hyd

Externí odkaz: https://doaj.org/article/780cfcea4e1d42239a438be5e9f7470f

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Akademický článek

Purinergic Receptors in Ocular Inflammation

Autor: Ana Guzman-Aranguez, Xavier Gasull, Yolanda Diebold, Jesús Pintor

Publikováno v: Mediators of Inflammation, Vol 2014 (2014)

Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease. When inflammation affects the eye, it can produce severe disorders affecting the superfic

Externí odkaz: https://doaj.org/article/0de1b8ae33d649f1a8859a35352a65f2

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Akademický článek

Targeted disruption of core 1 β1,3-galactosyltransferase (C1galt1) induces apical endocytic trafficking in human corneal keratinocytes.

Autor: Ana Guzman-Aranguez, Ashley M Woodward, Jesús Pintor, Pablo Argüeso

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36628 (2012)

Exposed mucosal surfaces limit constitutive endocytosis under physiological conditions to prevent uptake of macromolecules and pathogens and, therefore, cellular damage. It is now accepted that cell surface mucins, a group of high molecular weight gl

Externí odkaz: https://doaj.org/article/d2bbbc24a2334b6e9be39e2cfd8a563b

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Publikováno v: Engineering, Vol 7, Iss 10, Pp 1393-1412 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Repisalud
Instituto de Salud Carlos III (ISCIII)
E-Prints Complutense. Archivo Institucional de la UCM

20 p.-9 fig.-2 tab.
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. The 5-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86d51ca069118b13e54f0905d1e72fc
http://www.sciencedirect.com/science/article/pii/S2095809921003258

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Effects of hyperosmolarity on annexin A1 on ocular surface epithelium in vitro

Autor: Miguel Angel Fernandez –Torres, Victoria Eugenia Lledó, Maria J Perez de Lara, Ana Guzman-Aranguez

Publikováno v: Experimental eye research. 224

Osmotic stress is an important challenge to cell function. Dry eye pathology is characterized by elevated tear film osmolarity as consequence of decreased tear secretion and/or increased evaporation. Dry eye pathogenesis is not completely clarified.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb6867cb8aa269d2eed90dab7a4de68
https://pubmed.ncbi.nlm.nih.gov/36087761

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