Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ana Gutiérrez-Fernández"'
Autor:
Pablo Bousquets-Muñoz, Ander Díaz-Navarro, Ferran Nadeu, Ana Sánchez-Pitiot, Sara López-Tamargo, Shimin Shuai, Milagros Balbín, Jose M. C. Tubio, Sílvia Beà, Jose I. Martin-Subero, Ana Gutiérrez-Fernández, Lincoln D. Stein, Elías Campo, Xose S. Puente
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Current somatic mutation callers are biased against repetitive regions, preventing the identification of potential driver alterations in these loci. We developed a mutation caller for repetitive regions, and applied it to study repetitive no
Externí odkaz:
https://doaj.org/article/5f0f3806b2a34e4faaa729f3e687de20
Autor:
Jesús Gutiérrez-Abril, Iñigo Santamaría, Ana S. Pitiot, Ana Gutiérrez-Fernández, Ángel Alvarez-Eguiluz, José M. Vicente, Carmen Sanzo, Soledad González-Muñiz, Milagros Balbín, Xose S. Puente
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
Externí odkaz:
https://doaj.org/article/0f2b5d7a763d4f18b570b3d0a351eb7b
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
Autor:
Emilio García-Prieto, Adrián González-López, Sandra Cabrera, Aurora Astudillo, Ana Gutiérrez-Fernández, Miriam Fanjul-Fernandez, Estefanía Batalla-Solís, Xose S Puente, Antonio Fueyo, Carlos López-Otín, Guillermo M Albaiceta
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13242 (2010)
BACKGROUND: Matrix metalloproteinases (MMPs) may have pro and antifibrotic roles within the lungs, due to its ability to modulate collagen turnover and immune mediators. MMP-8 is a collagenase that also cleaves a number of cytokines and chemokines. M
Externí odkaz:
https://doaj.org/article/5b7768d5472f4696aa696a4237a03c84
Autor:
Carlos López-Otín, Xose S. Puente, Fred C.G.J. Sweep, Paul N. Span, J. Louise Jones, Deborah L. Holliday, Dylan R. Edwards, Simon Pilgrim, Caroline J. Pennington, Cecilia Garabaya, Alicia R. Folgueras, Antonio Fueyo, Ana Gutiérrez-Fernández
Supplementary Figure 1 from Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e711a6632d64015dc9850ddc2f0e13
https://doi.org/10.1158/0008-5472.22374980.v1
https://doi.org/10.1158/0008-5472.22374980.v1
Autor:
Carlos López-Otín, Xose S. Puente, Fred C.G.J. Sweep, Paul N. Span, J. Louise Jones, Deborah L. Holliday, Dylan R. Edwards, Simon Pilgrim, Caroline J. Pennington, Cecilia Garabaya, Alicia R. Folgueras, Antonio Fueyo, Ana Gutiérrez-Fernández
Collagenase-2 (matrix metalloproteinase-8, MMP-8) is an MMP mainly produced by neutrophils and associated with many inflammatory conditions. We have previously described that MMP-8 plays a protective role in cancer through its ability to regulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52502d9be0b2e1d17402c309bcb9012
https://doi.org/10.1158/0008-5472.c.6497663
https://doi.org/10.1158/0008-5472.c.6497663
Autor:
Pablo Bousquets-Muñoz, Ander Díaz-Navarro, Ferran Nadeu, Ana Sánchez-Pitiot, Sara López-Tamargo, Shimin Shuai, Milagros Balbín, Jose M. C. Tubio, Sílvia Beà, Jose I. Martin-Subero, Ana Gutiérrez-Fernández, Lincoln D. Stein, Elías Campo, Xose S. Puente
Publikováno v:
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Current somatic mutation callers are biased against repetitive regions, preventing the identification of potential driver alterations in these loci. We developed a mutation caller for repetitive regions, and applied it to study repetitive non protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779db51463f337c2f8607f8a9face0d9
https://pubmed.ncbi.nlm.nih.gov/35288589
https://pubmed.ncbi.nlm.nih.gov/35288589
Autor:
Sara González-Rodríguez, Ana Gutiérrez-Fernández, Ana Baamonde, Luis Menéndez, Mario García-Domínguez, Agustín Hidalgo, Ana Lastra, Alina Aguirre
Publikováno v:
Biochemical pharmacology. 175
As recently described, the administration of extremely low doses (pg/kg) of CCL4 (Macrophage inflammatory protein 1β, MIP-1β) can induce antinociceptive effects in mice (Garcia-Dominguez et al., 2019b). We describe here that hydrodynamic delivery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfd7d2c1a11b7b01146739a08dc131e
https://pubmed.ncbi.nlm.nih.gov/32156658
https://pubmed.ncbi.nlm.nih.gov/32156658
Autor:
Estefanía Batalla-Solís, Ana Gutiérrez-Fernández, Carlos Mayoral-Garcia, Guillermo M. Albaiceta, Jorge Blázquez-Prieto, Inés López-Alonso, Moisés Sánchez-Pérez, Laura Amado-Rodríguez, Adrián González-López, Alina Aguirre
Publikováno v:
Journal of Molecular Medicine. 95:487-497
Matrix metalloproteinases can modulate the inflammatory response through processing of cyto- and chemokines. Among them, MMP-14 is a non-dispensable collagenase responsible for the activation of other enzymes, triggering a proteolytic cascade. To ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed080ac3b6bc3f421311dbc0ee1b3e04
https://doi.org/10.1007/s00109-017-1510-z
https://doi.org/10.1007/s00109-017-1510-z
Autor:
Carlos López-Otín, Chana Vinkler, Meytal Landau, Ana Gutiérrez-Fernández, Xose S. Puente, Shai Marcu, Doron M. Behar, Mordechai Shohat, Eyal Reinstein, Dana Irge, Einav Tayeb-Fligelman, Shay Tzur, Annick Raas-Rothschild, Concetta Bormans
Publikováno v:
European Journal of Human Genetics. 24:1792-1796
In the vast majority of pediatric patients with dilated cardiomyopathy, the specific etiology is unknown. Studies on families with dilated cardiomyopathy have exemplified the role of genetic factors in cardiomyopathy etiology. In this study, we appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62005c494373c8171e9b721b860a74e6
https://doi.org/10.1038/ejhg.2016.110
https://doi.org/10.1038/ejhg.2016.110
Autor:
Anne Jouvet, Ana Gutiérrez-Fernández, Namal Abeysundara, Olivier Ayrault, Vijay Ramaswamy, Charles G. Eberhart, Jennifer A. Chan, Johan M. Kros, Xiaochong Wu, Sachin Kumar, Seung-Ki Kim, Maria C. Vladoiu, Noriyuki Kijima, Xose S. Puente, Ian F. Pollack, Robert J. Wechsler-Reya, Boleslaw Lach, Almos Klekner, Ander Diaz-Navarro, Claudia C. Faria, Lincoln Stein, Nicole Gauer, Enrique López-Aguilar, Nada Jabado, Amulya A. Nageswara Rao, Livia Garzia, David Malkin, Stefan M. Pfister, Jiannis Ragoussis, Maura Massimino, James M. Olson, Caterina Giannini, Hamza Farooq, Pim J. French, Florence M.G. Cavalli, Anna Goldenberg, John A. Calarco, Joshua B. Rubin, Maria Luisa Garrè, Betty Luu, László Bognár, Weifan Dong, Shimin Shuai, Antoine Forget, Jun Wang, Ichiyo Shibahara, Pasqualino De Antonellis, William A. Weiss, Marco A. Marra, Lola B. Chambless, Patryk Skowron, Wiesława Grajkowska, Jiao Zhang, Ali Momin, Erwin G. Van Meir, Michelle Fèvre-Montange, Rajeev Vibhakar, Ho Keung Ng, David Przelicki, Hiromichi Suzuki, Kyle Juraschka, Craig Daniels, A. Sorana Morrissy, Toshihiro Kumabe, Xi Huang, Wai Sang Poon, Swneke D. Bailey, Michael D. Taylor
Publikováno v:
Nature, 574(7780), 707-+. Nature Publishing Group
Nature
Nature, Nature Publishing Group, 2019
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature
Nature, Nature Publishing Group, 2019
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Author(s), under exclusive licence to Springer Nature Limited 2019
In cancer, recurrent somatic single-nucleotide variants-which are rare in most paediatric cancers-are confined largely to protein-coding genes1-3. Here we report highly re
In cancer, recurrent somatic single-nucleotide variants-which are rare in most paediatric cancers-are confined largely to protein-coding genes1-3. Here we report highly re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf69b6fedf20eee2d65c01dc77b0345b
https://pure.eur.nl/en/publications/87b8ce9e-154a-4fc3-baab-ad9bad99de72
https://pure.eur.nl/en/publications/87b8ce9e-154a-4fc3-baab-ad9bad99de72