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Autor:
Ilse Gijselinck, Christine Van Broeckhoven, Karolien Bettens, Helen Van Miegroet, Karin Peeters, Kristel Sleegers, Nathalie Brouwers, Ana Gil Montoya, Peter Paul De Deyn, Maria Mattheijssens, Sebastiaan Engelborghs, Barbara A. Pickut, Marc Cruts
Publikováno v:
Journal of Alzheimer's disease
The nuclear transactive response (TAR) DNA binding protein-43, TDP-43, is a major constituent of the ubiquitinated neuronal inclusions in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). Missense mutatio