Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ana Garcia, Diaz"'
Autor:
Antoni Olona, Ximena Terra, Jeong-Hun Ko, Carme Grau-Bové, Montserrat Pinent, Anna Ardevol, Ana Garcia Diaz, Aida Moreno-Moral, Matthew Edin, David Bishop-Bailey, Darryl C. Zeldin, Timothy J. Aitman, Enrico Petretto, Mayte Blay, Jacques Behmoaras
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 18-32 (2018)
Objective: When molecular drivers of healthy adipogenesis are perturbed, this can cause hepatic steatosis. The role of arachidonic acid (AA) and its downstream enzymatic cascades, such as cyclooxygenase, in adipogenesis is well established. The exact
Externí odkaz:
https://doaj.org/article/d7285575e91349bf8008e12a518b25d1
Autor:
Philip M. Coan, Oliver Hummel, Ana Garcia Diaz, Marjorie Barrier, Neza Alfazema, Penny J. Norsworthy, Michal Pravenec, Enrico Petretto, Norbert Hübner, Timothy J. Aitman
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 297-306 (2017)
We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identi
Externí odkaz:
https://doaj.org/article/217f43e21ad843a2903c54aea3fe26e6
Autor:
Tabitha Turner-Stokes, Maria Prendecki, Kevin J. Woollard, Stephen P. McAdoo, Damilola Pinheiro, Ana Garcia Diaz, Charles D. Pusey, H. Terence Cook, Candice Roufosse
Publikováno v:
J Am Soc Nephrol
Background Immune complexes within glomerular capillary walls cause crescentic GN (CrGN). Monocytes and macrophages are important in mediating CrGN, but little work has been done to phenotype the subpopulations involved and determine their respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39bcc3b750a36ac33d0c83b25e77894f
https://doi.org/10.1681/asn.2019121326
https://doi.org/10.1681/asn.2019121326
Autor:
Maria Prendecki, Stephen P McAdoo, Tabitha Turner‐Stokes, Ana Garcia‐Diaz, Isabel Orriss, Kevin J Woollard, Jacques Behmoaras, H Terence Cook, Robert Unwin, Charles D Pusey, Timothy J Aitman, Frederick WK Tam
Publikováno v:
Prendecki, M, McAdoo, S P, Turner-Stokes, T, Garcia-Diaz, A, Orriss, I, Woollard, K J, Behmoaras, J, Cook, H T, Unwin, R, Pusey, C D, Aitman, T J & Tam, F W K 2022, ' Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways ', The Journal of Pathology . https://doi.org/10.1002/path.5890
P2RX7, an ionotropic receptor for extracellular ATP, is expressed on immune cells, including macrophages, monocytes and dendritic cells and is up-regulated on non-immune cells following injury. P2RX7 plays a role in many biological processes, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c46de18f19c0559eb5617cd175e75a
https://www.pure.ed.ac.uk/ws/files/262724468/The_Journal_of_Pathology_2022_Prendecki_Glomerulonephritis_and_autoimmune_vasculitis_are_independent_of_P2RX7_but_may.pdf
https://www.pure.ed.ac.uk/ws/files/262724468/The_Journal_of_Pathology_2022_Prendecki_Glomerulonephritis_and_autoimmune_vasculitis_are_independent_of_P2RX7_but_may.pdf
Autor:
Nada Abdelmagid, Biborka Bereczky-Veress, Santosh Atanur, Alena Musilová, Václav Zídek, Laura Saba, Andreas Warnecke, Mohsen Khademi, Marie Studahl, Elisabeth Aurelius, Anders Hjalmarsson, Ana Garcia-Diaz, Cécile V Denis, Tomas Bergström, Birgit Sköldenberg, Ingrid Kockum, Timothy Aitman, Norbert Hübner, Tomas Olsson, Michal Pravenec, Margarita Diez
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155832 (2016)
Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain. Although viral latency in neurons is very common in the population, it remains unclear why certai
Externí odkaz:
https://doaj.org/article/6a186948765c434db82250a5c6150623
Autor:
Nur Hayati Jasmin, Angela Richard-Loendt, Kevin J. Woollard, Daniel J. Stuckey, Ana Garcia Diaz, Valerie Taylor Cummings, Mark F. Lythgoe, Tabitha Turner-Stokes, Marc J. George, Aroon D. Hingorani, Derek W. Gilroy, Francesca Launchbury
Publikováno v:
JACC: Basic to Translational Science, Vol 6, Iss 5, Pp 431-443 (2021)
Summary Interleukin (IL)-6 is an emerging therapeutic target in myocardial infarction (MI). IL-6 has 2 distinct signaling pathways: trans-signaling, which mediates inflammation, and classic signaling, which also has anti-inflammatory effects. The nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50cdb217113807f986ddaebfe6d911c
https://pubmed.ncbi.nlm.nih.gov/34102669
https://pubmed.ncbi.nlm.nih.gov/34102669
Autor:
Mark J. Arends, David Ross, Marjorie Barrier, Julie Moss, P. M. Coan, Timothy J. Aitman, Adrian Thomson, Sophie Marion de Procé, Zoe Webster, Neza Alfazema, Roderick N. Carter, Nicholas M. Morton, Ben Moyon, Lucy H. Jackson-Jones, Ana Garcia Diaz, Xaquin Castro Dopico
Publikováno v:
Coan, P, Barrier, M, Alfazema, N, Carter, R N, Marion de Proce, S, Castro Dopico, X, Diaz, A G, Thomson, A J W, Jackson-Jones, L, Moyon, B, Webster, Z, Ross, D, Moss, J, Arends, M J, Morton, N M & Aitman, T J 2017, ' COMPLEMENT FACTOR B IS A DETERMINANT OF BOTH METABOLIC AND CARDIOVASCULAR FEATURES OF METABOLIC SYNDROME ', Hypertension . https://doi.org/10.1161/HYPERTENSIONAHA.117.09242
Hypertension (Dallas, Tex. : 1979)
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
CFB (complement factor B) is elevated in adipose tissue and serum from patients with type 2 diabetes mellitus and cardiovascular disease, but the causal relationship to disease pathogenesis
CFB (complement factor B) is elevated in adipose tissue and serum from patients with type 2 diabetes mellitus and cardiovascular disease, but the causal relationship to disease pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558294a6213e4c9d50777cc98d4c3b87
https://doi.org/10.1161/hypertensionaha.117.09242
https://doi.org/10.1161/hypertensionaha.117.09242
Autor:
Robert J. Unwin, Terry Cook, Tabitha Turner-Stokes, Frederick W.K. Tam, Jacques Behmoaras, Stephen P. McAdoo, Ana Garcia-Diaz, Maria Prendecki, Kevin J. Woollard, Timothy J. Aitman, Charles D. Pusey
Publikováno v:
Rheumatology. 58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98715de708a2a0ea247c04ea0c7b0838
https://doi.org/10.1093/rheumatology/kez061.026
https://doi.org/10.1093/rheumatology/kez061.026
Autor:
Timothy J. Aitman, Alex Montoya, Lara Venda, Enrico Petretto, Ana Garcia Diaz, Jacques Behmoaras, Ben Moyon, Peter Faull, Jeong-Hun Ko, Zoe Webster, Charles D. Pusey, Prashant K. Srivastava, David Abraham, Terence Cook
Publikováno v:
The Journal of Immunology. 194:4705-4716
Epoxygenases belong to the cytochrome P450 family. They generate epoxyeicosatrienoic acids, which are known to have anti-inflammatory effects, but little is known about their role in macrophage function. By high-throughput sequencing of RNA in primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26db898c7fcb0a201cb6e18d0bfb4ce
https://doi.org/10.4049/jimmunol.1402979
https://doi.org/10.4049/jimmunol.1402979
Autor:
Penny J. Norsworthy, Marjorie Barrier, Enrico Petretto, Ana Garcia Diaz, Michal Pravenec, Timothy J. Aitman, Neza Alfazema, P. M. Coan, Norbert Huebner, Oliver Hummel
Publikováno v:
Disease Models & Mechanisms
Coan, P M, Hummel, O, Diaz, A I G, Barrier, M, Alfazema, N, Norsworthy, P J, Pravenec, M, Petretto, E, Huebner, N & Aitman, T J 2017, ' Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat ', Disease Models and Mechanisms, vol. 10, no. 3 . https://doi.org/10.1242/dmm.026716
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 297-306 (2017)
Coan, P M, Hummel, O, Diaz, A I G, Barrier, M, Alfazema, N, Norsworthy, P J, Pravenec, M, Petretto, E, Huebner, N & Aitman, T J 2017, ' Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat ', Disease Models and Mechanisms, vol. 10, no. 3 . https://doi.org/10.1242/dmm.026716
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 297-306 (2017)
We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3704a7fcfb6fc2bae8fed27c2ce63346
http://edoc.mdc-berlin.de/16293/1/16293oa.pdf
http://edoc.mdc-berlin.de/16293/1/16293oa.pdf