Silymarin: A Natural Compound for Obesity Management

Autor: Jessica Alves de Freitas, Aline Boveto Santamarina, José Pinhata Otoch, Ana Flávia Marçal Pessoa

Publikováno v: Obesities, Vol 4, Iss 3, Pp 292-313 (2024)

Silybum marianum (L.) Gaertn, commonly known as milk thistle, is an herbal medicine rich in silymarin, a bioflavonoid complex. Historically, silymarin was used for treating liver diseases, but recent studies highlight silymarin’s potential for obes

Externí odkaz: https://doaj.org/article/1312ed4dce12443a9578c48cceaa164d

Novel Nutraceutical (silymarin, yeast β-glucan, prebiotics, and minerals) shifts gut microbiota and restores large intestine histology of diet-induced metabolic syndrome mice

Autor: Victor Nehmi-Filho, Jessica Alves de Freitas, Lucas Augusto Moysés Franco, Joyce Vanessa da Silva Fonseca, Roberta Cristina Ruedas Martins, Aline Boveto Santamarina, Gilson Masahiro Murata, Ester Cerdeira Sabino, Erica Souza, Matthew Thomas Ferreira, José Pinhata Otoch, Ana Flávia Marçal Pessoa

Publikováno v: Journal of Functional Foods, Vol 107, Iss , Pp 105671- (2023)

Gut dysbiosis contributes to chronic inflammation and oxidative stress associated with metabolic syndrome, and non-pharmacological, health-promoting supplements like nutraceuticals have been studied and used as a way to prevent or treat several illne

Externí odkaz: https://doaj.org/article/2f0b7d3a7afa44f6a6f3d8ff2dd88414

The Symbiotic Effect of a New Nutraceutical with Yeast β-Glucan, Prebiotics, Minerals, and Silybum marianum (Silymarin) for Recovering Metabolic Homeostasis via Pgc-1α, Il-6, and Il-10 Gene Expression in a Type-2 Diabetes Obesity Model

Autor: Aline Boveto Santamarina, Ruan Carlos Macêdo Moraes, Victor Nehmi Filho, Gilson Masahiro Murata, Jéssica Alves de Freitas, Danielle Araujo de Miranda, Anderson Romério Azevedo Cerqueira, Soraia Katia Pereira Costa, Ana Flávia Fernandes Ferreira, Luiz Roberto Britto, Juliana Alves de Camargo, Daniela Rodrigues de Oliveira, Flavia Neto de Jesus, José Pinhata Otoch, Ana Flávia Marçal Pessoa

Publikováno v: Antioxidants, Vol 11, Iss 3, p 447 (2022)

The use of natural products and derivatives for the prevention and control of non-communicable chronic diseases, such as type-2 diabetes (T2D), obesity, and hepatic steatosis is a way to achieve homeostasis through different metabolic pathways. Thus,

Externí odkaz: https://doaj.org/article/47f4f913cc024b19ac4e30ca3f7f9aaf

A novel supplement with yeast β-glucan, prebiotic, minerals and Silybum marianum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice

Autor: Gilson Masahiro Murata, Ruan Pimenta, Nayara I. Viana, Katrin Radloff, Danielle Araujo de Miranda, Jéssica Alves De Freitas, Gabriely Cristina Alves Lima, Raquel Galvão Figueredo Costa, Victor Abou Nehmi, Joyce de Cassia Rosa de Jesus, José Pinhata Otoch, Ana Flávia Marçal Pessoa, Ruan Carlos Macêdo de Moraes, Katia R. M. Leite

Publikováno v: Journal of integrative medicine. 19(5)

Objective To evaluate the synergic effects of a novel oral supplement formulation, containing prebiotics, yeast β-glucans, minerals and silymarin (Silybum marianum), on lipid and glycidic metabolism, inflammatory and mitochondrial proteins of the li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f8948977bae2980f8bcde2f51170cc
https://pubmed.ncbi.nlm.nih.gov/34108131

High prevalence of malnutrition in Internal Medicine wards–a multicentre ANUMEDI study

Autor: A. Marinho, J. Rosinhas, Bruno Oliveira, S. Silva, Harriët Jager-Wittenaar, J. Silveira, Ana Flávia Marçal Pessoa, Marta B. Lopes, A. Amado, R.C. Marinho, João Pedro Pinho

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
European Journal of Internal Medicine, 76, 82-88. Elsevier Science
European Journal of Internal Medicine, 76, 82-88. ELSEVIER SCIENCE BV

Background: Disease-related malnutrition is a significant problem in hospitalized patients, with high prevalence rates depending on the studied population. Internal Medicine wards are the backbone of the hospital setting. However, prevalence and dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84453ee7abb85c824efb7a58f596048