Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ana Fernandez-Ruiz"'
Autor:
Yan Burelle, Gerardo Ferbeyre, Marc J. Servant, Murray Baron, Alexanne Cuillerier, Nesrine Fazez, David N. Huynh, Mariana Acevedo, Ozge Kizilay Mancini, Ana Fernandez Ruiz
Publikováno v:
Rheumatology (Oxford, England). 61(3)
Objective SSc is an autoimmune connective tissue disorder characterized by inflammation and fibrosis. Although constitutive activation of fibroblasts is proposed to be responsible for the fibrotic and inflammatory features of the disease, the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7363ee1b69d21ada06a8adabcf485ba3
https://pubmed.ncbi.nlm.nih.gov/34115840
https://pubmed.ncbi.nlm.nih.gov/34115840
Autor:
Gerardo Ferbeyre, Paloma Kalegari, Lian Mignacca, Frédéric Lessard, Jan Pencik, Geneviève Huot, Jordan Quenneville, Marie-Camille Rowell, Laura Hulea, Jacob Bouchard, Stéphane Lopes-Paciencia, Michael Pollak, Oro Uchenunu, Ana Fernandez-Ruiz, Katja Julissa Ponce, Etienne Gagnon, Nhung Vuong, Véronique Bourdeau, Mehdi Benfdil, Haytham M. Wahba, Ivan Topisitrovic, James G. Omichinski, Richard Moriggl, Antonio Nanci, Sebastian Igelmann, Aurélien Fouillen, David Papadopoli, Lukas Kenner
Publikováno v:
SSRN Electronic Journal.
Metabolic rewiring and redox balance play pivotal roles in cancer. Cellular senescence is a barrier for tumorigenesis circumvented in cancer cells by poorly understood mechanisms. We report a novel multi-enzymatic complex that reprograms NAD metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9ba7a35c7f68a80a84e12eade3c594f
https://doi.org/10.2139/ssrn.3753808
https://doi.org/10.2139/ssrn.3753808
Autor:
Oro Uchenunu, Gerardo Ferbeyre, James G. Omichinski, Paloma Kalegari, David Papadopoli, Antonio Nanci, Ivan Topisirovic, Jordan Quenneville, Sebastian Igelmann, Laura Hulea, Aurélien Fouillen, Lukas Kenner, Jordan Guillon, Véronique Bourdeau, Haytham M. Wahba, Jacob Bouchard, Etienne Gagnon, Richard Moriggl, Mehdi Benfdil, Jan Pencik, Marie-Camille Rowell, Katia Julissa Ponce, Frédéric Lessard, Lian Mignacca, Stéphane Lopes-Paciencia, Michael Pollak, Ana Fernandez-Ruiz, Geneviève Huot, Nhung Vuong
Publikováno v:
Molecular Cell. 81:3848-3865.e19
Metabolic rewiring and redox balance play pivotal roles in cancer. Cellular senescence is a barrier for tumorigenesis circumvented in cancer cells by poorly understood mechanisms. We report a multi-enzymatic complex that reprograms NAD metabolism by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd9ac33bfd391617e3ed4d32b35759f
https://doi.org/10.1016/j.molcel.2021.08.028
https://doi.org/10.1016/j.molcel.2021.08.028
Autor:
Ana Fernandez Ruiz, Maxime Parisotto, Gerardo Ferbeyre, Audrey Hébert, Paloma Kalegari, Andreea R. Schmitzer, Guillaume Lefrancois, Marie-Camille Rowell, Alexandra Doré
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
We present the design and synthesis of a small library of substituted biguanidium salts and their capacity to inhibit the growth/viability of pancreatic cancer cells. We first present their in vitro and membrane activity, before we address their mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d854daacf9d8b0e22ae6a7bbbb76174
Autor:
Gerardo Ferbeyre, Paloma Kalegari, Léa Brakier-Gingras, Emmanuelle Saint-Germain, Sebastian Igelmann, Mehdi Benfdil, Lian Mignacca, Véronique Bourdeau, Marie-Camille Rowell, Neylen Del Toro, Ana Fernandez-Ruiz, Frédéric Lessard, Stéphane Lopes-Paciencia
Senescence is a tumor suppressor program characterized by a stable growth arrest while maintaining cell viability. Senescence-associated ribogenesis defects (SARD) have been shown to regulate senescence through the ability of the ribosomal protein S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba23de22e1eda67ba431f1b1cd846602
https://europepmc.org/articles/PMC6464582/
https://europepmc.org/articles/PMC6464582/
Autor:
Jose Soto-Sonera, Víctor Bonilla-Rodríguez, Melitza Nieves-Viera, Kevin Vargas Vélez, Ana Fernández-Ruiz de Alegría
Publikováno v:
Ciencia y Educación, Vol 7, Iss 3 (2023)
Este estudio tuvo como propósito presentar los resultados de la construcción y el proceso de recopilación de evidencias de validez del cuestionario Posturas acerca de la evolución biológica y su enseñanza. Es la primera investigación en Puerto
Externí odkaz:
https://doaj.org/article/f4ee6e127d044c89894640e47a354782
Autor:
Ana Fernandez Ruiz, Filippos Kottakis, Benjamin Le Calvé, Stéphane Lopes-Paciencia, Nabeel Bardeesy, Xavier Deschênes-Simard, Marie-Camille Rowell, Gerardo Ferbeyre
Publikováno v:
Cancer Research. 78:462-462
This study aims to better understand the loss of tumor -uppression functions of ERK in pancreatic cancer progression. Pancreatic cancer is the 4th leading cause of death by cancer in Canada and USA with a 5-year survival rate below 7%. We have identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e5d80dd2ba655ca2b82e0e7f8765962
https://doi.org/10.1158/1538-7445.am2018-462
https://doi.org/10.1158/1538-7445.am2018-462
Autor:
Cristina Pericet-Rodríguez, Francisco José Hidalgo-Lesmes, Rafael González-Manzanares, Soledad Ojeda-Pineda, Aurora Luque-Moreno, Javier Suárez de Lezo, Miguel Ángel Romero-Moreno, Francisco Mazuelos-Bellido, José María Segura Saint-Gerons, Ana Fernández-Ruiz, María Guisela Flores-Vergara, Manuel Pan Álvarez-Ossorio
Publikováno v:
REC: Interventional Cardiology, Vol 3, Iss 3, Pp 182-189 (2021)
RESUMEN Introducción y objetivos: El propósito del estudio fue describir nuestra experiencia con el uso del índice diastólico instantáneo sin ondas (iFR) para la evaluación fisiológica coronaria o el uso del software Syncvision/iFR (Syncvision
Externí odkaz:
https://doaj.org/article/8f244cfc9da548ab9abbcea5fad01e2b
Autor:
Cristina Pericet-Rodríguez, Francisco José Hidalgo-Lesmes, Rafael González-Manzanares, Soledad Ojeda-Pineda, Aurora Luque-Moreno, Javier Suárez de Lezo, Miguel Ángel Romero-Moreno, Francisco Mazuelos-Bellido, José María Segura Saint-Gerons, Ana Fernández-Ruiz, María Guisela Flores-Vergara, Manuel Pan Álvarez-Ossorio
Publikováno v:
REC: Interventional Cardiology (English Ed.), Vol 3, Iss 3, Pp 182-189 (2021)
ABSTRACT Introduction and objectives: The objective of this study was to describe our experience with coronary physiology assessment using the instantaneous wave-free ratio (iFR) and/or a Syncvision-guided iFR-pullback study [Syncvision version 4.1.0
Externí odkaz:
https://doaj.org/article/93b861057e9745f2bf75369db8b7e843
Autor:
Audrey Hébert, Maxime Parisotto, Marie-Camille Rowell, Alexandra Doré, Ana Fernandez Ruiz, Guillaume Lefrançois, Paloma Kalegari, Gerardo Ferbeyre, Andreea R. Schmitzer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We present the design and synthesis of a small library of substituted biguanidium salts and their capacity to inhibit the growth of pancreatic cancer cells. We first present their in vitro and membrane activity, before we address their mecha
Externí odkaz:
https://doaj.org/article/6a200413183b471cb0be937679e2ef46