Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ana Fernandez Villegas"'
Autor:
Amberley D. Stephens, Ana Fernandez Villegas, Chyi Wei Chung, Oliver Vanderpoorten, Dorothea Pinotsi, Ioanna Mela, Edward Ward, Thomas M. McCoy, Robert Cubitt, Alexander F. Routh, Clemens F. Kaminski, Gabriele S. Kaminski Schierle
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Monomeric alpha-synuclein (aSyn) is a well characterised protein that importantly binds to lipids. aSyn monomers assemble into amyloid fibrils which are localised to lipids and organelles in insoluble structures found in Parkinson’s diseas
Externí odkaz:
https://doaj.org/article/47a85327169c4aaf9bffa1e9000eb692
Autor:
Jeffrey Mc Hugh, Stanislaw Makarchuk, Daria Mozheiko, Ana Fernandez-Villegas, Gabriele S. Kaminski Schierle, Clemens Kaminski, Ulrich Keyser, David Holcman, Nathalie Rouach
Publikováno v:
Nanoscale.
Dendrites and dendritic spines are the essential cellular compartments in neuronal communication, conveying information through transient voltage signals. Our understanding of these compartmentalized voltage dynamics in fine, distal neuronal dendrite
Autor:
Amberley D. Stephens, Ana Fernandez Villegas, Chyi Wei Chung, Oliver Vanderpoorten, Dorothea Pinotsi, Ioanna Mela, Edward Ward, Thomas M. McCoy, Robert Cubitt, Alexander F. Routh, Clemens F. Kaminski, Gabriele S. Kaminski Schierle
Monomeric alpha-synuclein (aSyn) is a well characterised as a lipid binding protein. aSyn is known to form amyloid fibrils which are also localised with lipids and organelles in so called Lewy bodies, insoluble structures found in Parkinson’s disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17e2e8cc3331fbaa56cabb3db6d5efd
https://doi.org/10.1101/2022.10.04.510646
https://doi.org/10.1101/2022.10.04.510646
Autor:
Katharina M. Scherer, Luca Mascheroni, George W. Carnell, Lucia C. S. Wunderlich, Stanislaw Makarchuk, Marius Brockhoff, Ioanna Mela, Ana Fernandez-Villegas, Max Barysevich, Hazel Stewart, Maria Suau Sans, Charlotte L. George, Jacob R. Lamb, Gabriele S. Kaminski-Schierle, Jonathan L. Heeney, Clemens F. Kaminski
Despite being the target of extensive research efforts due to the COVID-19 (coronavirus disease 2019) pandemic, relatively little is known about the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication within cells. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cee3a6a1f486de24a79e2cfe610a726
https://www.repository.cam.ac.uk/handle/1810/332628
https://www.repository.cam.ac.uk/handle/1810/332628
Publikováno v:
ACS Chemical Neuroscience
The Alzheimer’s disease related peptide, Amyloid-beta (Aβ)1–40 and 1–42, has proven difficult to be purified as a recombinant monomeric protein due its expression in E. coli leading to the formation of insoluble inclusion bodies and its tenden
Autor:
Zixuan Lu, Chiara Barberio, Ana Fernandez‐Villegas, Aimee Withers, Alexandra Wheeler, Konstantinos Kallitsis, Eleonora Martinelli, Achilleas Savva, Becky M. Hess, Anna‐Maria Pappa, Gabriele S. Kaminski Schierle, Róisín M. Owens
Publikováno v:
Advanced Science, Vol 11, Iss 27, Pp n/a-n/a (2024)
Abstract Drug studies targeting neuronal ion channels are crucial to understand neuronal function and develop therapies for neurological diseases. The traditional method to study neuronal ion‐channel activities heavily relies on the whole‐cell pa
Externí odkaz:
https://doaj.org/article/096d55a692a94d6ea7e3e0a09313df3a
Autor:
Raimund Jung, Marie C Lechler, Ana Fernandez-Villegas, Chyi Wei Chung, Harry C Jones, Yoon Hee Choi, Maximilian A Thompson, Christian Rödelsperger, Waltraud Röseler, Gabriele S Kaminski Schierle, Ralf J Sommer, Della C David
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002284 (2023)
During aging, proteostasis capacity declines and distinct proteins become unstable and can accumulate as protein aggregates inside and outside of cells. Both in disease and during aging, proteins selectively aggregate in certain tissues and not other
Externí odkaz:
https://doaj.org/article/6e413ad3f27943b5974f39bac00f3cda