Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ana Cristina Vargas Calderon"'
Autor:
Harvey W. Smith, Alison Hirukawa, Virginie Sanguin-Gendreau, Ipshita Nandi, Catherine R. Dufour, Dongmei Zuo, Kristofferson Tandoc, Matthew Leibovitch, Salendra Singh, Jonathan P. Rennhack, Matthew Swiatnicki, Cynthia Lavoie, Vasilios Papavasiliou, Carolin Temps, Neil O. Carragher, Asier Unciti-Broceta, Paul Savage, Mark Basik, Vincent van Hoef, Ola Larsson, Caroline L. Cooper, Ana Cristina Vargas Calderon, Jane Beith, Ewan Millar, Christina Selinger, Vincent Giguère, Morag Park, Lyndsay N. Harris, Vinay Varadan, Eran R. Andrechek, Sandra A. O’Toole, Ivan Topisirovic, William J. Muller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Polycomb Repressor Complex 2 (PRC2) is frequently up-regulated in cancers. Here, the authors show that the tyrosine kinase c-Src stimulates mitochondrial function to signal energy sufficiency to mTORC1, increasing translation of the PRC2 subunits EZH
Externí odkaz:
https://doaj.org/article/4b4ac9959bb3404bb739e2634c53409f
Autor:
Ana Cristina Vargas Calderon, Tsu-Hui Hubert Low, Christina I. Selinger, Ruta Gupta, Harini Narayanappa
Publikováno v:
Pathology. 50:356-358
Autor:
Salendra Singh, Vasilios Papavasiliou, Catherine R. Dufour, Jane Beith, Ipshita Nandi, Eran R. Andrechek, Virginie Sanguin-Gendreau, Ewan K.A. Millar, Lyndsay Harris, Asier Unciti-Broceta, Mark Basik, Harvey W. Smith, Sandra A O'Toole, Carolin Temps, Vincent van Hoef, Vinay Varadan, Vincent Giguère, Cynthia Lavoie, Matthew R. Swiatnicki, Ola Larsson, Paul Savage, Alison Hirukawa, Kristofferson Tandoc, Jonathan P. Rennhack, Christina I. Selinger, Matthew Leibovitch, Neil O. Carragher, Ana Cristina Vargas Calderon, Ivan Topisirovic, Dongmei Zuo, Morag Park, Caroline Cooper, William J. Muller
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Dysregulation of histone modifications promotes carcinogenesis by altering transcription. Breast cancers frequently overexpress the histone methyltransferase EZH2, the catalytic subunit of Polycomb Repressor Complex 2 (PRC2). However, the role of EZH