Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ana Cristina Guerra Souza"'
Autor:
Julia M, Rosa, Francis L, Pazini, Mauricio P, Cunha, André R S, Colla, Luana M, Manosso, Gianni, Mancini, Ana Cristina Guerra, Souza, Andreza F, de Bem, Rui Daniel, Prediger, Ana Lúcia S, Rodrigues
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 86
Alzheimer's disease (AD) is characterized by progressive synaptic dysfunction and neuronal lost in specific brain areas including hippocampus, resulting in memory/learning deficits and cognitive impairments. In addition, non-cognitive symptoms are re
Autor:
Francine C. Paim, Fabiano B. Carvalho, Sonia Terezinha dos Anjos Lopes, Bibiana M. Gai, Cinthia M. Mazzanti, Silvia Gonzalez Monteiro, Cristina W. Nogueira, Michelle Melgarejo da Rosa, Patrícia Wolkmer, Ana Cristina Guerra Souza, Aleksandro Schafer da Silva, Paula R. Pereira, Maribel Antonello Rubin, Cássia B. da Silva
Publikováno v:
Parasitology. 140:1432-1441
SUMMARYThe aim of this study was to investigate neurochemical and enzymatic changes in rats infected withTrypanosoma evansi, and their interference in the cognitive parameters. Behavioural assessment (assessment of cognitive performance), evaluation
Autor:
Ana Cristina Guerra Souza, César Augusto Brüning, Carmine Inês Acker, Cristina W. Nogueira, José S. S. Neto
Publikováno v:
Behavioural Pharmacology. 24:249-254
Taking into account the memory-enhancing properties of 2-phenylethynyl-butyltellurium (PEBT) and the constant search for drugs that improve cognitive performance, the present study was designed to investigate the effect of PEBT on cognitive impairmen
Autor:
Ana Cristina Guerra Souza, Cecília M. P. Rodrigues, Rita M. Ramalho, Simone Pinton, Cristina W. Nogueira, Marcel Henrique Marcondes Sari
Publikováno v:
Behavioural Brain Research. 247:241-247
Behavioral evidence suggests that the organoselenium compound p , p ′-methoxyl-diphenyl diselenide [(MeOPhSe) 2 ] ameliorates memory and learning performance in rodents. Here, we investigated the molecular mechanism of (MeOPhSe) 2 neuroprotection i
Autor:
Marcel Henrique Marcondes Sari, Ana Cristina Guerra Souza, Cristina W. Nogueira, Cristiane Luchese, José S. S. Neto, Simone Pinton
Publikováno v:
Journal of Neuroscience Research. 91:848-853
Our previous study demonstrated that 2-phenylethynyl-butyltellurium (PEBT), an organotellurium compound, enhances memory in mice. In this study, the effects of PEBT on cognitive impairment induced by Aβ25-35 were assessed by Morris water maze and st
Autor:
Ethel A. Wilhelm, Ana Cristina Guerra Souza, Pietro Maria Chagas, Cristina W. Nogueira, Bibiana Mozzaquatro Gai, Juliano A. Roehrs
Publikováno v:
Life Sciences. 90:666-672
Aims In this study we investigated the effect of pre-treatment with 3-alkynyl selenophene (3-ASP) against the increase in responsiveness to pentylenetetrazole [PTZ seizure threshold] and cognitive dysfunction induced by experimental febrile seizures
Autor:
Ana Cristina Guerra Souza, Carmine Inês Acker, Cristina W. Nogueira, Bibiana M. Gai, Michael D. Costa, Ricardo Brandão
Publikováno v:
Chemico-Biological Interactions. 197:80-86
The present study investigated the effect of ebselen (EB) against hyperglycemia induced by the organophosphate (OPI) diazinon (DI) in rats. The insulin-mimetic properties of EB were investigated in vitro with the aim of better understanding the hypog
Autor:
Maurício Portella dos Santos, Cristina W. Nogueira, Carmine Inês Acker, Ana Cristina Guerra Souza, Cinthia M. Mazzanti
Publikováno v:
Environmental Science and Pollution Research. 19:3481-3490
In this study, we investigated the effect of diphenyl diselenide [(PhSe)(2)] on chlorpyrifos (CPF)-induced hepatic and hematologic toxicity in rats.Rats were pre-treated with (PhSe)(2) (5 mg/kg) via the oral route (oral gavage) once a day for 7 days.
Autor:
Cristiano Rodrigo Bohn Rhoden, Catiane B. Alves, Cristiane Luchese, Ana Cristina Guerra Souza, Marta P. Alves, Francine R. Ianiski, Simone Pinton, Silvane Souza Roman
Publikováno v:
Behavioural Brain Research. 230:100-107
The objective of present study was to investigate the protective effect of M-NC against aβ (25–35) peptide-induced damage in mice, as the first step to evaluate their potential value for the treatment of AD. Moreover, we compared the effects of M-
Autor:
Ricardo F. Schumacher, Ana Cristina Guerra Souza, Gilson Zeni, Carmine Inês Acker, Alisson R. Rosario, Cristina W. Nogueira
Publikováno v:
Bioorganic & Medicinal Chemistry. 19(4):1418-1425
Here we present our results in palladium cross-coupling reaction of aryl boronic acids with 4-iodo-2,3-dihydroselenophene derivatives. The cross-coupled products were obtained in satisfactory yields. A dehydrogenation of4,5-diphenyl-2,3-dihydroseleno