Brazilian Guidelines for transcranial doppler in children and adolescents with sickle cell disease

Autor: Clarisse Lopes de Castro Lobo, Rodolfo Delfini Cançado, Ana Claudia Celestino Bezerra Leite, Ana Claudia Mendonça dos Anjos, Ana Cristina Silva Pinto, Andre Palma da Cunha Matta, Célia Maria Silva, Gisele Sampaio Silva, João Ricardo Friedrisch, Josefina Aparecida Pellegrini Braga, Marcos Christiano Lange, Maria Stella Figueiredo, Marília Álvares Rugani, Orlando Veloso, Patrícia Gomes Moura, Paulo Ivo Cortez, Robert Adams, Sandra Fátima Menosi Gualandro, Shirley Lopes de Castilho, Ursula Thomé, Viviane Flumignan Zetola

Publikováno v: Revista Brasileira de Hematologia e Hemoterapia, Vol 33, Iss 1, Pp 43-48 (2011)

BACKGROUND: Sickle cell disease is the most common monogenic hereditary disease in Brazil. Although strokes are one of the main causes of morbidity and mortality in these patients, the use of transcranial Doppler to identify children at risk is not u

Externí odkaz: https://doaj.org/article/419146d56716416796ca8cf81fec6e0a

Alpha thalassemia, but not βS-globin haplotypes, influence sickle cell anemia clinical outcome in a large, single-center Brazilian cohort

Autor: Marcondes José de Vasconcelos Costa Sobreira, Aderson S Araujo, Antonio R. Lucena-Araujo, Flávia Peixoto Albuquerque, Isabela Cristina Cordeiro Farias, Danízia Menezes de Lima Silva, Diego A Pereira-Martins, Manuela Albuquerque de Melo, Bruna Vasconcelos de Ancântara, Gabriela da Silva Arcanjo, Diego Arruda Falcão, Ana Claudia Mendonça dos Anjos, A. S. Araújo, Magnun N. N. Santos, Rodrigo Marcionilo Santana, Thais Helena Chaves Batista, Isabel Weinhäuser, Jéssica Vitória Gadelha de Freitas Batista, Betânia Lucena Domingues Hatzlhofer, Ana Beatriz Lucas de Moura Rafael, Luana Priscilla Laranjeira Prado, Igor de Farias Domingos, Fernando Ferreira Costa, Marcos André Cavalcanti Bezerra, Juan L Coelho-Silva, Jéssica Maria Florencio Oliveira

Publikováno v: Annals of Hematology. 100:921-931

Alpha thalassemia and beta-globin haplotype are considered classical genetic disease modifiers in sickle cell anemia (SCA) causing clinical heterogeneity. Nevertheless, their functional impact on SCA disease emergence and progression remains elusive.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8810ea8b501d301689840d84ff5bdbe7
https://doi.org/10.1007/s00277-021-04450-x

Os polimorfismos do gene MBL2 não estão relacionados com a ocorrência de doença cerebrovascular na anemia falciforme

Autor: Betânia Lucena Domingues Hatzlhofer, Taciana Furtado Mendonça-Belmont, Antonio R. Lucena-Araujo, Igor de Farias Domingos, João Victor Cordeiro Farias, Marcos André Cavalcanti Bezerra, Maria do Socorro de Mendonça Cavalcanti, Isabela Cristina Cordeiro Farias, Luydson Richardson Silva Vasconcelos, Patrícia Muniz Mendes Freire de Moura, Diego Arruda Falcão, Aderson S Araujo, Gabriela da Silva Arcanjo, Kleyton Palmeira do Ó, Andreia Soares da Silva, Ana Claudia Mendonça dos Anjos

Publikováno v: Research, Society and Development, Vol 9, Iss 7, Pp e439974240-e439974240 (2020)
Research, Society and Development; Vol. 9 No. 7; e439974240
Research, Society and Development; Vol. 9 Núm. 7; e439974240
Research, Society and Development; v. 9 n. 7; e439974240
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI

Objective: This study has as objective to verify whether MBL2 gene polymorphisms are related to the occurrence of cerebrovascular disease (CD) in sickle cell anemia (SCA) patients. Methods: Overall, 259 unrelated SCA patients were enrolled. The patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953ccedc820f6570ad7507edbed4127d
http://rsd.unifei.edu.br/index.php/rsd/article/view/4240

Combined genotypes of the MBL2 gene related to low mannose-binding lectin levels are associated with vaso-occlusive events in children with sickle cell anemia

Autor: Luydson Richardson Silva Vasconcelos, Fernanda Silva Medeiros, Marcos André Cavalcanti Bezerra, Aderson S Araujo, Maria do Carmo Valgueiro Costa de Oliveira, Patrícia Moura, Betânia Lucena Domingues Hatzlhofer, Taciana Furtado de Mendonça, Katiuscia Araújo de Miranda Lopes, Laís Medeiros da Câmara França, Andreia Soares da Silva, Ana Claudia Mendonça dos Anjos, Maria do Socorro de Mendonça Cavalcanti

Publikováno v: Genetics and Molecular Biology v.40 n.3 2017
Genetics and Molecular Biology
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Volume: 40, Issue: 3, Pages: 600-603, Published: 21 AUG 2017
Genetics and Molecular Biology, Vol 40, Iss 3, Pp 600-603 (2017)

Sickle cell anemia (SCA) presents heterogenous clinical manifestations that cannot be explained solely by alterations to hemoglobin (Hb); other components such as endothelial adhesion, thrombosis and inflammation may be involved. The mannose-binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e9182c13d908ad354c8f0ccc963db5
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400600

Association of the SOD2 polymorphism (Val6Ala) and SOD activity with vaso-occlusive crisis and acute splenic sequestration in children with sickle cell anemia

Autor: Kleyton Palmeira do Ó, Taciana Furtado Mendonça-Belmont, Isabela Cristina Cordeiro Farias, Patrícia Muniz Mendes Freire de Moura, Fernanda Silva Medeiros, Maria do Socorro de Mendonça Cavalcanti, Ana Claudia Mendonça dos Anjos, Betânia Lucena Domingues Hatzlhofer, Aderson S Araujo, Luydson Richardson Silva Vasconcelos, Felipe A. B. S. Ferreira, Marcos André Cavalcanti Bezerra, Andreia Soares da Silva

Publikováno v: Mediterranean Journal of Hematology and Infectious Diseases, Vol 10, Iss 1, Pp e2018012-e2018012 (2018)

The SOD2 polymorphism Val16Ala TàC influences the antioxidative response. This study investigated the association of the SOD2 polymorphism and superoxide dismutase (SOD) activity with vaso-occlusive crisis (VOC) and acute splenic sequestration (ASS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd25ca2f60f8d2f0fdb3f8977de3e7b
https://doi.org/10.4084/mjhid.2018.012