Long-term blood-free rearing of Anopheles mosquitoes with no effect on fitness, Plasmodium infectivity nor microbiota composition

Autor: Joana Marques, Sofia G. Seabra, Inês Almeida, Joana Gomes, Ana Catarina Alves, Henrique Silveira

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract Mosquito-borne diseases kill millions of people each year. Therefore, many innovative research and population control strategies are being implemented but, most of them require large-scale production of mosquitoes. Mosquito rearing depends o

Externí odkaz: https://doaj.org/article/caca083e98df4c8baf49332914946cff

Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype

Autor: Ana Margarida Medeiros, Ana Catarina Alves, Beatriz Miranda, Joana Rita Chora, Mafalda Bourbon, Quitéria Rato, Ana Catarina Gomes, Ana Cristina Ferreira, Ana Gaspar, Ana Margarida Marques, Ana Maria Garabal, Ana Paula Bogalho, Ana Rita Pereira, Anabela Raimundo, André Travessa, Andreia Lopes, António Afonso, António Furtado, António Guerra, António Monteiro, António Trindade, Armindo Ribeiro, Bernardo Dias Pereira, Bernardo Marques, Carla Laranjeira, Catarina Senra Moniz, Cecília Frutuoso, Cláudia Falcão Reis, Cláudia Rodrigues, Clementina Fernandes, Conceição Ferreira, Daniel Ferreira, Diogo Torres, Elisabete Martins, Elsa Gaspar, Fabiana Pimentel, Fernando Simões, Francisco Araújo, Francisco Silva, Goreti Lobarinhas, Graça Morais, Guida Gama, Guilherme Lourenço, Helena Mansilha, Helena Pereira, Heloísa Santos, Henedina Antunes, Inês Batista Gomes, Inês Colaço, Isabel Azevedo, Isabel Palma, João Anselmo, João Porto, João Ramos, João Sequeira Duarte, Jorge Pintado Alves, José Miguel Salgado, José Pereira de Moura, Leonor Sassetti, Lina Cardoso Ramos, Luísa Diogo Matos, Luísa Mota Vieira, Luísa Pires, Márcio de Moura, Margarida Bruges, Margarida Venâncio, Maria do Rosário Barroso, Maria João Virtuoso, Maria Luísa Gonçalves, Mário Martins Oliveira, Mendes Nunes, Miguel Costa, Miguel Mendes, Miguel Toscano Rico, Mónica Tavares, Natalina Miguel, Oana Moldovan, Olga Azevedo, Patrícia Lipari Pinto, Patrícia Pais, Patrícia Vasconcelos, Paula Garcia, Paula Martins, Pedro Marques da Silva, Piedade Lemos, Raquel Coelho, Raquel Gouveia da Silva, Raquel Ribeiro, Rita Jotta de Oliveira, Roberto Pinto, Sandra Pereira, Sérgio Ferreira Cristina, Sílvia Sequeira, Susana Correia, Tânia Vassalo, Tiago Pack, Vânia Martins, Vera Frazão Vieira

Publikováno v: Journal of Lipid Research, Vol 65, Iss 2, Pp 100490- (2024)

Familial hypercholesterolemia (FH) is a common genetic disorder of lipid metabolism caused by pathogenic/likely pathogenic variants in LDLR, APOB, and PCSK9 genes. Variants in FH-phenocopy genes (LDLRAP1, APOE, LIPA, ABCG5, and ABCG8), polygenic hype

Externí odkaz: https://doaj.org/article/68a8ff206df9455cbff0bf939698e1bb

Symptoms and factors associated with symptom clusters among older adults with oral and oropharyngeal cancers at diagnosis

Autor: Ana Catarina Alves e Silva, Izabella Costa Santos, Cleber Nascimento do Carmo, Inês Echenique Mattos

Publikováno v: Geriatrics, Gerontology and Aging, Vol 15, Pp 1-10 (2022)

OBJECTIVE: Describe differences in pretreatment symptoms and the composition of symptom clusters in older patients with oral and oropharyngeal cancer. METHODS: In this cross-sectional study, quality of life (QoL) assessments for cancer patients (EORC

Externí odkaz: https://doaj.org/article/52d7d4bfa4c54cd693c1234879199218

Performance comparison of different classification algorithms applied to the diagnosis of familial hypercholesterolemia in paediatric subjects

Autor: João Albuquerque, Ana Margarida Medeiros, Ana Catarina Alves, Mafalda Bourbon, Marília Antunes

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Familial Hypercholesterolemia (FH) is an inherited disorder of lipid metabolism, characterized by increased low density lipoprotein cholesterol (LDLc) levels. The main purpose of the current work was to explore alternative classification met

Externí odkaz: https://doaj.org/article/e773b47fa3034ebba661640df61139d6

Aplicabilidade da fórmula Martin‐Hopkins e comparação com a fórmula Friedewald na estimativa do colesterol LDL na população do estudo e_COR

Autor: Cátia Ferrinho, Ana Catarina Alves, Mafalda Bourbon, Sequeira Duarte

Publikováno v: Revista Portuguesa de Cardiologia, Vol 40, Iss 10, Pp 715-724 (2021)

Resumo: Introdução: O colesterol LDL (cLDL) é essencial na abordagem do risco de doenças cardiovasculares. Desde 1972 é utilizada a fórmula de Friedewald para estimativa da concentração do cLDL, com algumas limitações. Foi sugerida, em 2013

Externí odkaz: https://doaj.org/article/76aa60a1389c4837b373ef8ea26a3d7d