Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ana Carolina Dantas Machado"'
Autor:
Ana Carolina Dantas Machado, Stephany Flores Ramos, Julia M. Gauglitz, Anne-Marie Fassler, Daniel Petras, Alexander A. Aksenov, Un Bi Kim, Michael Lazarowicz, Abbey Barnard Giustini, Hamed Aryafar, Irine Vodkin, Curtis Warren, Pieter C. Dorrestein, Ali Zarrinpar, Amir Zarrinpar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Elective transjugular intrahepatic portosystemic shunt (TIPS) placement can worsen cognitive dysfunction in hepatic encephalopathy (HE) patients due to toxins, including possible microbial metabolites, entering the systemic circulation. We c
Externí odkaz:
https://doaj.org/article/03208619f93e4d158a10efaafebd0c4d
Autor:
Ana Carolina Dantas Machado, Steven D. Brown, Amulya Lingaraju, Vignesh Sivaganesh, Cameron Martino, Amandine Chaix, Peng Zhao, Antonio F.M. Pinto, Max W. Chang, R. Alexander Richter, Alan Saghatelian, Alan R. Saltiel, Rob Knight, Satchidananda Panda, Amir Zarrinpar
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111008- (2022)
Summary: Compositional oscillations of the gut microbiome are essential for normal peripheral circadian rhythms, both of which are disrupted in diet-induced obesity (DIO). Although time-restricted feeding (TRF) maintains circadian synchrony and prote
Externí odkaz:
https://doaj.org/article/5d7baa7f81854be59e805862d41bfb1b
Autor:
Celeste Allaband, Amulya Lingaraju, Cameron Martino, Baylee Russell, Anupriya Tripathi, Orit Poulsen, Ana Carolina Dantas Machado, Dan Zhou, Jin Xue, Emmanuel Elijah, Atul Malhotra, Pieter C. Dorrestein, Rob Knight, Gabriel G. Haddad, Amir Zarrinpar
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
People with obstructive sleep apnea, identified by loud snoring and breathing irregularly while sleeping, are at a higher risk of high blood pressure, type 2 diabetes, cardiac arrhythmias, stroke, and sudden cardiac death. We wanted to understand whe
Externí odkaz:
https://doaj.org/article/429dcc19d03e4a30bd1d554e3f64a1e2
Autor:
Y. Paul Chang, Meng Xu, Ana Carolina Dantas Machado, Xian Jessica Yu, Remo Rohs, Xiaojiang S. Chen
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1117-1127 (2013)
The DNA tumor virus Simian virus 40 (SV40) is a model system for studying eukaryotic replication. SV40 large tumor antigen (LTag) is the initiator/helicase that is essential for genome replication. LTag recognizes and assembles at the viral replicati
Externí odkaz:
https://doaj.org/article/fb04f728d0c64f5ca115b0b3c00ad683
Autor:
Yongheng Chen, Darren L. Bates, Raja Dey, Po-Han Chen, Ana Carolina Dantas Machado, Ite A. Laird-Offringa, Remo Rohs, Lin Chen
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1197-1206 (2012)
GATA transcription factors regulate transcription during development and differentiation by recognizing distinct GATA sites with a tandem of two conserved zinc fingers, and by mediating long-range DNA looping. However, the molecular basis of these pr
Externí odkaz:
https://doaj.org/article/736900e0c8384678923d76d0433d55eb
Publikováno v:
Nucleic Acids Research.
Quantifying the nucleotide preferences of DNA binding proteins is essential to understanding how transcription factors (TFs) interact with their targets in the genome. High-throughput in vitro binding assays have been used to identify the inherent DN
Autor:
Ana Carolina Dantas Machado, Stephany Flores Ramos, Julia M. Gauglitz, Anne-Marie Carpenter, Daniel Petras, Alexander A. Aksenov, Un Bi Kim, Michael Lazarowicz, Abbey Barnard Giustini, Hamed Aryafar, Irine Vodkin, Curtis Warren, Pieter C. Dorrestein, Ali Zarrinpar, Amir Zarrinpar
Publikováno v:
medRxiv
Hepatic encephalopathy (HE) is a common complication of advanced liver disease causing brain dysfunction. This is likely due to the accumulation of unfiltered toxins within the bloodstream. A known risk factor for developing or worsening HE is the pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8853f528a9c8c4233e96573e6223344
https://europepmc.org/articles/PMC9882439/
https://europepmc.org/articles/PMC9882439/
Autor:
Celeste Allaband, Amulya Lingaraju, Stephany Flores Ramos, Tanya Kumar, Haniyeh Javaheri, Maria D. Tiu, Ana Carolina Dantas Machado, Roland A. Richter, Emmanuel Elijah, Gabriel G. Haddad, Vanessa A. Leone, Pieter C. Dorrestein, Rob Knight, Amir Zarrinpar
Although many aspects of microbiome studies have been standardized to improve experimental replicability, none account for how the daily diurnal fluctuations in the gut lumen cause dynamic changes in 16S amplicon sequencing. Here we show that sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776057daa0f51246962486b7008f8ba7
https://doi.org/10.1101/2022.10.26.513817
https://doi.org/10.1101/2022.10.26.513817
Publikováno v:
Nucleic Acids Research
Myocyte enhancer factor-2B (MEF2B) has the unique capability of binding to its DNA target sites with a degenerate motif, while still functioning as a gene-specific transcriptional regulator. Identifying its DNA targets is crucial given regulatory rol
Autor:
Yukiko Miyamoto, Nicole Siguenza, Alan Saghatelian, Ana Carolina Dantas Machado, Erica S. Maissy, R. Alexander Richter, Rob Knight, Samuel B. Ho, Steven D. Brown, Baylee J. Russell, Antonio Pinto, Amir Zarrinpar, Anand R. Saran, Jeff Hasty, Lars Eckmann, Amulya Lingaraju, Irene Mai
Live bacterial therapeutics (LBT) could reverse disease by engrafting in the gut and providing persistent beneficial functions in the host. However, attempts to functionally manipulate the gut microbiome of conventionally-raised (CR) hosts have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aed7f7216b077e431738bcb8a1108a4
https://doi.org/10.1101/2021.11.11.468006
https://doi.org/10.1101/2021.11.11.468006