Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension

Autor: Patricia B. Munroe, Martin Farrall, John Webster, Morris J. Brown, Pamela J. Kaisaki, Peng Y. Woon, Ana Carolina B. Marçano, Nilesh J. Samani, John M. C. Connell, Anna F. Dominiczak, Mark J. Caulfield, Mark Lathrop, Johannie Gungadoo, Beverley Burke, David Clayton, Dominique Gauguier, Chris Wallace

BACKGROUND: Inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) is a negative regulator of insulin signalling and has previously been found to be associated with hypertension, obesity and type 2 diabetes in a cohort of families with diabetes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6780fa5d016d0f14b3e204de5cba25f5
https://ora.ox.ac.uk/objects/uuid:2a9366f0-45c9-4680-9818-0f31ae42dfe3

BHS Abstracts

Autor: Anna F. Dominiczak, Morris J. Brown, N J Samani, Steven Newhouse, John Webster, Patricia B. Munroe, Martin Farrall, Chris Wallace, Abiodun Onipinla, Mark J. Caulfield, Beverley Burke, Ana Carolina B. Marçano, Mimoza Hoti, Charles A. Mein, Richard Dobson, David Clayton, Connell Jmc., Mark Lathrop

Publikováno v: Journal of Human Hypertension

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a745130d69317e88be5da204692cc4
https://doi.org/10.1038/sj.jhh.1002270

Glutathione S-transferase variants and hypertension

Autor: Mark J. Caulfield, Christian Delles, Roland E. Schmieder, John D. McClure, Martin Farrall, Sandosh Padmanabhan, Patricia B. Munroe, Wai K. Lee, Morris J. Brown, Nick J.R. Brain, William H. Miller, John Webster, Chris Wallace, Ana Carolina B. Marçano, John M. C. Connell, Anna F. Dominiczak, Martin W. McBride

Publikováno v: Journal of hypertension. 26(7)

OBJECTIVES: Glutathione S-transferases are involved in defences against oxidative stress. We have recently demonstrated reduced expression of glutathione S-transferase mu type 1 (Gstm1) in a rat model of hypertension. Here, we examine the association

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http://ora.ox.ac.uk/objects/uuid:d34dd9ae-f9f5-48d1-bc8c-6dd0e3f6f731

CONTRIBUTORS

Autor: Vineeta Ahooja, Vamadevan S. Ajay, Laurence Amar, Lawrence J. Appel, Michel Azizi, George L. Bakris, Lydia A. Bazzano, D. Gareth Beevers, Lawrence J. Beilin, Andrew D. Blann, Matthew A. Boegehold, George W. Booz, Branko Braam, Elizabeth L. Brandon, Michael W. Brands, Mark Britton, Hans R. Brunner, Beverley Burke, Valerie Burke, Francesco P. Cappuccio, Robert M. Carey, Barry L. Carter, Mark J. Caulfield, Yuqing Chen, Jay N. Cohn, John M.C. Connell, Anthony Cox, Madhusudan Das, Kevin P. Davy, Cheryl R. Dennison, Shant Der Sarkissian, Javier Díez, Peter A. Doris, Heather A. Drummond, Daniel A. Duprez, Fernando Elijovich, Henry L. Elliott, William J. Elliott, David J. Eveson, Gregory D. Fink, Nicola Fiotti, John M. Flack, Joseph T. Flynn, Pierre Foëx, Lourdes A. Fortepiani, Martin D. Fotherby, Fetnat Fouad-Tarazi, Stanley S. Franklin, Ryan Friese, John W. Funder, James J. Galligan, Jeffrey L. Garvin, Christopher L. Gentile, Jacob George, Lorenzo Ghiadoni, Carlo Giansante, Richard E. Gilbert, Sabas I. Gomez, Alan H. Gradman, Joey P. Granger, Guido Grassi, Philip Greenland, Ehud Grossman, Johannie Gungadoo, John A. Haas, Peter Y. Hahn, John E. Hall, Bruce A. Hamilton, Joseph R. Haywood, Jiang He, Marcela Herrera, Martha N. Hill, Radu Iliescu, Chris Isles, Joseph L. Izzo, Rumi Jaumdally, Daniel W. Jones, Patricia M. Kearney, Hein A. Koomans, Richard A. Krasuski, Henry Krum, Cheryl L. Laffer, Chim C. Lang, Nigel J. Langford, Debbie A. Lawlor, Dexter L. Lee, Bernard I. Lévy, Daniel Link, Gregory Y.H. Lip, Graham W. Lipkin, Donald M. Lloyd-Jones, Thomas E. Lohmeier, Brona V. Loughrey, Thomas M. MacDonald, Robert J. MacFadyen, Sushil K. Mahata, Giuseppe Mancia, Ana Carolina B. Marçano, Jennifer Martin, John C. McGiff, Gordon T. McInnes, Franz H. Messerli, Steven M. Miller, Paul Mitchell, Jason Moore, Trevor A. Mori, Marvin Moser, Maryann N. Mugo, Patricia B. Munroe, Nitish Naik, Samar A. Nasser, Stephen J. Newhouse, Leong L. Ng, Carrie A. Northcott, Shannon M. O'Connor, Daniel T. O'Connor, Suzanne Oparil, Pablo A. Ortiz, Gurusher S. Panjrath, Hari Krishnan Parthasarathy, Ivan J. Perry, Thomas G. Pickering, Pierre-François Plouin, Dorairaj Prabhakaran, Ian B. Puddey, John Quilley, Mohan K. Raizada, Fangwen Rao, Jane F. Reckelhoff, Kolli Srinath Reddy, Damiano Rizzoni, J. Ian S. Robertson, Thompson G. Robinson, J. Carlos Romero, Enrico Agabiti Rosei, Talma Rosenthal, Dieter Rosskopf, Michael J. Ryan, Michel E. Safar, Antonio Salvetti, Panteleimon A. Sarafidis, Julio C. Sartori-Valinotti, Nicholas J. Schork, John F. Setaro, N.C. Shah, Julian Shiel, Ernesto L. Schiffrin, Domenic A. Sica, Alexandre A. da Silva, Guillermo B. Silva, J. Enrique Silva, George Davey Smith, Virend K. Somers, James R. Sowers, J. David Spence, Adrian G. Stanley, David E. Stec, Saverio Stranges, Allan D. Struthers, Craig S. Stump, Fatiha Tabet, Stefano Taddei, Laurent Taupenot, Muzahir H. Tayebjee, Cleber E. Teixeira, Keshari M. Thakali, Rhian M. Touyz, Darren Traub, Hung-Fat Tse, Jason G. Umans, Puchimada Uthappa, Anna B. Valina-Toth, George I. Varughese, Agostino Virdis, Stephanie W. Watts, R. Clinton Webb, Gen Wen, Paul K. Whelton, Judith A. Whitworth, Tien Yin Wong, Ryan M. Woodham, Kathleen Wyne, Licy Lorena Yanes, Zhekang Ying, Ian S. Young, Alberto Zanchetti, Kuixing Zhang, Lian Zhang, Michael G. Ziegler

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f625ff194d4966e4360e4be1098e6d86
https://doi.org/10.1016/b978-0-323-03961-1.50002-7

Recent advances in the identification of genes for human hypertension

Autor: Mark J. Caulfield, Patricia B. Munroe, Ana Carolina B. Marçano, Abiodun Onipinla

Publikováno v: Expert review of cardiovascular therapy. 3(4)

It is a well-established fact that genes are involved in the etiology of hypertension. However, identification of the gene variants still remains a challenge. Over the years, different approaches and technologies, including genome-wide scans, case-co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8610fd058433d8bb07aa1e208631a55
https://pubmed.ncbi.nlm.nih.gov/16076282