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Akademický článek

Early Interactions of Murine Macrophages with Francisella tularensis Map to Mouse Chromosome 19

Autor: Avner Fink, Musa A. Hassan, Nihal A. Okan, Michal Sheffer, Ana Camejo, Jeroen P. J. Saeij, Dennis L. Kasper

Publikováno v: mBio, Vol 7, Iss 2 (2016)

ABSTRACT Differences among individuals in susceptibility to infectious diseases can be modulated by host genetics. Much of the research in this field has aimed to identify loci within the host genome that are associated with these differences. In mic

Externí odkaz: https://doaj.org/article/93e1f57b28df4c19b8f08d7f48160d00

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Akademický článek

Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination

Autor: Kirk D. C. Jensen, Ana Camejo, Mariane B. Melo, Cynthia Cordeiro, Lindsay Julien, Gijsbert M. Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh, Lucy Young, Jeroen P. J. Saeij

Publikováno v: mBio, Vol 6, Iss 2 (2015)

ABSTRACT The intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species globally. Infection in most hosts causes a lifelong chronic infection and generates immunological memory responses that protect the host against new in

Externí odkaz: https://doaj.org/article/951858ac1fa54bed8b243d41124cc44a

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Akademický článek

In vivo transcriptional profiling of Listeria monocytogenes and mutagenesis identify new virulence factors involved in infection.

Autor: Ana Camejo, Carmen Buchrieser, Elisabeth Couvé, Filipe Carvalho, Olga Reis, Pierre Ferreira, Sandra Sousa, Pascale Cossart, Didier Cabanes

Publikováno v: PLoS Pathogens, Vol 5, Iss 5, p e1000449 (2009)

Listeria monocytogenes is a human intracellular pathogen able to colonize host tissues after ingestion of contaminated food, causing severe invasive infections. In order to gain a better understanding of the nature of host-pathogen interactions, we s

Externí odkaz: https://doaj.org/article/abe6cdd4a62a44ae828c3cb43c9cf83c

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Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway andToxoplasma gondiiROP5

Autor: Debanjan Mukhopadhyay, Jeroen P. J. Saeij, Angel K. Kongsomboonvech, Brayan E. Castallanos, Kirk D. C. Jensen, Gregory A. Taylor, Brandon M. Justice, Ana Camejo, Michael L. Reese, Felipe Rodriguez, Anh L. Diep, Masahiro Yamamoto

Publikováno v: PLoS Pathogens
PLoS pathogens, vol 16, iss 8
PLoS Pathogens, Vol 16, Iss 8, p e1008327 (2020)

Host resistance to Toxoplasma gondii relies on CD8 T cell IFNγ responses, which if modulated by the host or parasite could influence chronic infection and parasite transmission between hosts. Since host-parasite interactions that govern this respons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee883bcb4b71414d0cf4d9b8b7f894
https://doi.org/10.1101/2020.01.20.912568

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Virulence gene repression promotes Listeria monocytogenes systemic infection

Autor: Didier Cabanes, Ana Camejo, Cristel Archambaud, Pascale Cossart, Rita Pombinho, Sandra Maria Zákia Lian Sousa, Ana Rita Vieira

Publikováno v: Gut Microbes
Gut microbes
Gut microbes, 2020, 11 (4), pp.868-881. ⟨10.1080/19490976.2020.1712983⟩
Gut microbes, Taylor & Francis, 2020, 11 (4), pp.868-881. ⟨10.1080/19490976.2020.1712983⟩

The capacity of bacterial pathogens to infect their hosts depends on the tight spatiotemporal regulation of virulence genes. The Listeria monocytogenes (Lm) metal efflux pump repressor CadC is highly expressed during late infection stages, modulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd4e2bbe4bc287351af4f1b7769dcca
https://europepmc.org/articles/PMC7524345/

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In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration

Autor: Antonio Barragan, Ninghan Yang, Ana Camejo, Sebastian Lourido, Saima M. Sidik, Einar B. Ólafsson, Lamba Omar Sangaré, Lindsay Julien, Yifan Wang, Patricia A. Pesavento, Jeroen P. J. Saeij

Publikováno v: Cell Host Microbe
PMC

Summary Toxoplasma can reach distant organs, especially the brain, leading to a lifelong chronic phase. However, genes involved in related in vivo processes are currently unknown. Here, we use focused CRISPR libraries to identify Toxoplasma genes tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880f798c1bcede3e183cac276e413354
https://pubmed.ncbi.nlm.nih.gov/31600500

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Control Issues

Autor: Ana Camejo

Publikováno v: Trends in Parasitology. 32:169-171

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d226aaae3a8008719c043f592dc8497
https://doi.org/10.1016/j.pt.2016.01.005

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Parasite Killers

Autor: Ana Camejo

Publikováno v: Trends in parasitology. 33(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ceac40644d20710f9aa72a1a3f1b058
https://pubmed.ncbi.nlm.nih.gov/28162935

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Listeria monocytogenes CadC Regulates Cadmium Efflux and Fine-tunes Lipoprotein Localization to Escape the Host Immune Response and Promote Infection

Autor: Rita Pombinho, Olga Reis, Didier Cabanes, Jorge Pinheiro, Sandra Maria Zákia Lian Sousa, Maria Teresa Almeida, Ana Vieira, Filipe Carvalho, Ana Camejo

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Listeria monocytogenes is a major intracellular human foodborne bacterial pathogen. We previously revealed L. monocytogenes cadC as highly expressed during mouse infection. Here we show that L. monocytogenes CadC is a sequence-specific, DNA-binding a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020f46e9a93fbcd39fc04e2ce51e6bc3
https://hdl.handle.net/10216/114553

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