Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Ana C Carrera"'
Autor:
Teresa M Zotes, Roberto Spada, Vladimir Mulens, Sonia Pérez-Yagüe, Carlos O Sorzano, Klaus Okkenhaug, Ana C Carrera, Domingo F Barber
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72960 (2013)
The role of p110δ PI3K in lymphoid cells has been studied extensively, showing its importance in immune cell differentiation, activation and development. Altered T cell localization in p110δ-deficient mouse spleen suggested a role for p110δ in non
Externí odkaz:
https://doaj.org/article/ff79f65af05b4a6b8c5b2ecb16c54709
Autor:
Teresa M Zotes, Cristina F Arias, José J Fuster, Roberto Spada, Sonia Pérez-Yagüe, Emilio Hirsch, Matthias Wymann, Ana C Carrera, Vicente Andrés, Domingo F Barber
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72674 (2013)
Atherosclerosis is an inflammatory disease regulated by infiltrating monocytes and T cells, among other cell types. Macrophage recruitment to atherosclerotic lesions is controlled by monocyte infiltration into plaques. Once in the lesion, macrophage
Externí odkaz:
https://doaj.org/article/ded248cc842d4a938df200b5578127f5
Autor:
Sudhanshu Yadav, Antonio Garrido, M. Carmen Hernández, Juan C. Oliveros, Vicente Pérez-García, Mario F. Fraga, Ana C. Carrera
Publikováno v:
WOS:000873961800006
The mechanism governing the transition of human embryonic stem cells (hESCs) toward differentiated cells is only partially understood. To explore this transition, the activity and expression of the ubiquitous phosphatidylinositol 3-kinase (PI3Kα and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9400f3d6d98f1847f0b08afca8e3d6f
https://doi.org/10.1016/j.stemcr.2022.09.003
https://doi.org/10.1016/j.stemcr.2022.09.003
Publikováno v:
Cancers. 14(22)
Phosphatidylinositol-3,4,5-triphosphate (PIP3) is a lipidic second messenger present at very low concentrations in resting normal cells. PIP3 levels, though, increase quickly and transiently after growth factor addition, upon activation of phosphatid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d66db01b08bd49fcb0722cdbb63d6e1
https://pubmed.ncbi.nlm.nih.gov/36428706
https://pubmed.ncbi.nlm.nih.gov/36428706
Autor:
Ariel E. Cariaga-Martínez, Isabel Cortés, Esther García, Vicente Pérez-García, María J. Pajares, Miguel A. Idoate, Javier Redondo-Muñóz, Inés M. Antón, Ana C. Carrera
Publikováno v:
Biology Open, Vol 3, Iss 10, Pp 924-936 (2014)
The acquisition of invasiveness is characteristic of tumor progression. Numerous genetic changes are associated with metastasis, but the mechanism by which a cell becomes invasive remains unclear. Expression of p85β, a regulatory subunit of phosphoi
Externí odkaz:
https://doaj.org/article/f52bdff3710043a4ae543d16b34112db
Autor:
Ana C. Carrera, Mario Mellado, Carmen Hernández, Laura Martínez-Muñoz, Miriam Sánchez-Ortega, Manuel Olazabal-Morán, Manuel S. Rodriguez
Publikováno v:
Cells
Cells, 2021, 10 (11), pp.2803. ⟨10.3390/cells10112803⟩
Volume 10
Issue 11
Cells, Vol 10, Iss 2803, p 2803 (2021)
Cells, 2021, 10 (11), pp.2803. ⟨10.3390/cells10112803⟩
Volume 10
Issue 11
Cells, Vol 10, Iss 2803, p 2803 (2021)
3-Poly-phosphoinositides (PIP3) regulate cell survival, division, and migration. Both PI3-kinase (phosphoinositide-3-kinase) and PTEN (phosphatase and tensin-homolog in chromosome 10) control PIP3 levels, but the mechanisms connecting PI3-kinase and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47ec08f11b33fd4fed5f6153e8fb280
https://hal.science/hal-03728095
https://hal.science/hal-03728095
Publikováno v:
Cells
Cells, Vol 10, Iss 1879, p 1879 (2021)
Cells, Vol 10, Iss 1879, p 1879 (2021)
The gene expression program induced by NRF2 transcription factor plays a critical role in cell defense responses against a broad variety of cellular stresses, most importantly oxidative stress. NRF2 stability is fine-tuned regulated by KEAP1, which d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29b6bf50621c0f079e99f15fcc8da88
https://doi.org/10.3390/cells10081879
https://doi.org/10.3390/cells10081879
Publikováno v:
Handbook of experimental pharmacology. 259
Despite interest in phosphoinositide (PtdIns) kinases, such as PtdIns 3 kinases (PI3K), as targets for controlling plasma membrane PtdIns levels in disease, the PtdIns have another less well-known site of action in the cell nucleus.Recent studies sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9bcc5025548d95e4d9935283c1eb48d
https://pubmed.ncbi.nlm.nih.gov/31201558
https://pubmed.ncbi.nlm.nih.gov/31201558
Autor:
Jesús Vallejo-Díaz, Manuel Olazabal-Morán, Ana González-García, Monica Chagoyen, Ana C. Carrera
Publikováno v:
Trends in Cancer.
Dysregulation of the PI3K/PTEN pathway is a frequent event in cancer, and PIK3CA and PTEN are the most commonly mutated genes after TP53. PIK3R1 is the predominant regulatory isoform of PI3K. PIK3R2 is an ubiquitous isoform that has been so far overl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3be131f3c9ab874e172c857b3d71402
http://hdl.handle.net/10261/241406
http://hdl.handle.net/10261/241406
Autor:
María M. Escribese, Francisco Vega, Santiago Martín, Tania Ramos, Ana C. Carrera, Alicia Marin, Rosa Varona, Peter Adler Würtzen, L Jimeno, Carlos Blanco, Agustin Galán, Domingo Barber
Publikováno v:
Allergy
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
© 2018 The Authors.
[Background]: In the first 2 years of grass tablet sublingual immunotherapy treatment, we have previously demonstrated a progressive development of a regulatory T‐cell response, which was preceded by an early decrease in t
[Background]: In the first 2 years of grass tablet sublingual immunotherapy treatment, we have previously demonstrated a progressive development of a regulatory T‐cell response, which was preceded by an early decrease in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab24fec4c187b18bf32e8f9921b41c3
http://hdl.handle.net/10261/240945
http://hdl.handle.net/10261/240945