Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ana C, Mengarda"'
Autor:
Vinícius Roquini, Ana C. Mengarda, Rayssa A. Cajas, Milene F. Martins-da-Silva, Julia Godoy-Silva, Gustavo A. Santos, Maria Cristina C. Espírito-Santo, Thais F. A. Pavani, Vanusa A. Melo, Maria C. Salvadori, Fernanda S. Teixeira, Daniela G. G. Rando, Josué de Moraes
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Schistosomiasis is a parasitic disease that afflicts approximately 250 million people worldwide. There is an urgent demand for new antiparasitic agents because praziquantel, the only drug available for the treatment of schistosomiasis, is no
Externí odkaz:
https://doaj.org/article/5dc2106a6f0f4e53872ac28a645be51f
Autor:
Cristiane S. Morais, Ana C. Mengarda, Fábio B. Miguel, Karine B. Enes, Vinícius C. Rodrigues, Maria Cristina C. Espírito-Santo, Abolghasem Siyadatpanah, Polrat Wilairatana, Mara R. C. Couri, Josué de Moraes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Praziquantel is the only available drug to treat schistosomiasis, a parasitic disease that currently infects more than 240 million people globally. Due to increasing concerns about resistance and inadequate efficacy there is a need for new t
Externí odkaz:
https://doaj.org/article/c796c9cec571489f881af2f237580804
Autor:
Taís C. Silva, Ana C. Mengarda, Bruna L. Lemes, Susana A. Z. Lescano, Dalete Christine S. Souza, João Henrique G. Lago, Josué de Moraes
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Infections caused by parasitic helminths have enormous health, social, and economic impacts worldwide. The treatment and control of these diseases have been dependent on a limited set of drugs, many of which have become less effective, neces
Externí odkaz:
https://doaj.org/article/f14ddbefcfe64b17a32f5728e5988292
Autor:
Rogério P. Xavier, Ana C. Mengarda, Marcos P. Silva, Daniel B. Roquini, Maria C. Salvadori, Fernanda S. Teixeira, Pedro L. Pinto, Thiago R. Morais, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Josué de Moraes
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background Schistosomiasis is a socioeconomically devastating parasitic infection afflicting hundreds of millions of people and animals worldwide. It is the most important helminth infection, and its treatment relies solely on the drug prazi
Externí odkaz:
https://doaj.org/article/2eb280a93e1a48be8e0834eceb1b9ebb
Autor:
Rafael L de Souza, Ana C Mengarda, Daniel B Roquini, Camila O Melo, Mayara C de Morais, Maria Cristina C Espírito-Santo, Damião P de Sousa, Josué de Moraes, Elquio E Oliveira
Publikováno v:
Nanomedicine. 18:331-342
Aim: To formulate a carvacryl acetate nanoemulsion (CANE) and test its antischistosomal activity. Materials & methods: CANE was prepared and tested in vitro on Schistosoma mansoni adult worms and both human and animal cell lines. Next, CANE was admin
Autor:
Raquel Porto, Ana C. Mengarda, Rayssa A. Cajas, Maria C. Salvadori, Fernanda S. Teixeira, Daniel D. R. Arcanjo, Abolghasem Siyadatpanah, Maria de Lourdes Pereira, Polrat Wilairatana, Josué de Moraes
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 686 (2021)
The intravascular parasitic worm Schistosoma mansoni is a causative agent of schistosomiasis, a disease of great global public health significance. Praziquantel is the only drug available to treat schistosomiasis and there is an urgent demand for new
Externí odkaz:
https://doaj.org/article/f7f321d9ff2d4322880338b152bfea77
Publikováno v:
Expert Opinion on Drug Delivery. 19:383-393
Infections caused by parasitic flatworms impose a considerable worldwide health burden. Recently, World Health Organization launched its roadmap for neglected diseases for the period 2021 to 2030 and oral treatment with praziquantel (PZQ) in tablet f
Autor:
Damião Pergentino de Sousa, Josué de Moraes, Rayssa A. Cajas, Maria Cristina Carvalho do Espírito-Santo, Bianca C. Silva, Ana C. Mengarda, Paulo U. Carnaúba, Carlos S. M. Bezerra-Filho, Vinícius C. Rodrigues
Publikováno v:
Parasitology Research. 120:3837-3844
Schistosomiasis is a major public health problem that afflicts more than 240 million individuals globally, particularly in poor communities. Treatment of schistosomiasis relies heavily on a single oral drug, praziquantel, and there is interest in the
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology. 15
Neglected tropical diseases (NTDs) remain major public health problems in developing countries. Reducing the burden of NTDs requires sustained collaborative drug discovery efforts to achieve the goals of the new NTDs roadmap launched by the World Hea
Autor:
Marcos P. Silva, Thiago R. Morais, Maria E. Cirino, Geanne A. Alves Conserva, Josué de Moraes, Ana C. Mengarda, João Henrique G. Lago
Publikováno v:
Phytotherapy Research. 35:5154-5162
Schistosomiasis is a widespread human parasitic disease currently affecting over 200 million people, particularly in poor communities. Chemotherapy for schistosomiasis relies exclusively on praziquantel (PZQ). Previous studies have shown that licarin