Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ana Bratic"'
Autor:
Jakob D. Busch, Miriam Cipullo, Ilian Atanassov, Ana Bratic, Eduardo Silva Ramos, Thomas Schöndorf, Xinping Li, Sarah F. Pearce, Dusanka Milenkovic, Joanna Rorbach, Nils-Göran Larsson
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1728-1738.e9 (2019)
Summary: Mitochondria harbor specialized ribosomes (mitoribosomes) necessary for the synthesis of key membrane proteins of the oxidative phosphorylation (OXPHOS) machinery located in the mitochondrial inner membrane. To date, no animal model exists t
Externí odkaz:
https://doaj.org/article/47fa904e13314d7a923559092c3f94f1
Autor:
Johanna H.K. Kauppila, Holly L. Baines, Ana Bratic, Marie-Lune Simard, Christoph Freyer, Arnaud Mourier, Craig Stamp, Roberta Filograna, Nils-Göran Larsson, Laura C. Greaves, James B. Stewart
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2980-2990 (2016)
Mutations of mtDNA are an important cause of human disease, but few animal models exist. Because mammalian mitochondria cannot be transfected, the development of mice with pathogenic mtDNA mutations has been challenging, and the main strategy has the
Externí odkaz:
https://doaj.org/article/c9d60e6d715741ada477ce9887a88f10
Autor:
Rafael Pérez-Pérez, Teresa Lobo-Jarne, Dusanka Milenkovic, Arnaud Mourier, Ana Bratic, Alberto García-Bartolomé, Erika Fernández-Vizarra, Susana Cadenas, Aitor Delmiro, Inés García-Consuegra, Joaquín Arenas, Miguel A. Martín, Nils-Göran Larsson, Cristina Ugalde
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2387-2398 (2016)
Mitochondrial respiratory chain (MRC) complexes I, III, and IV associate into a variety of supramolecular structures known as supercomplexes and respirasomes. While COX7A2L was originally described as a supercomplex-specific factor responsible for th
Externí odkaz:
https://doaj.org/article/57f6b2a6d31a4e268acc95b07dda5358
Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation.
Autor:
Ana Bratic, Paula Clemente, Javier Calvo-Garrido, Camilla Maffezzini, Andrea Felser, Rolf Wibom, Anna Wedell, Christoph Freyer, Anna Wredenberg
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006028 (2016)
Polyadenylation has well characterised roles in RNA turnover and translation in a variety of biological systems. While polyadenylation on mitochondrial transcripts has been suggested to be a two-step process required to complete translational stop co
Externí odkaz:
https://doaj.org/article/257f25870f65415ca39d229a709091a7
Autor:
Anna Wredenberg, Marie Lagouge, Ana Bratic, Metodi D Metodiev, Henrik Spåhr, Arnaud Mourier, Christoph Freyer, Benedetta Ruzzenente, Luke Tain, Sebastian Grönke, Francesca Baggio, Christian Kukat, Elisabeth Kremmer, Rolf Wibom, Paola Loguercio Polosa, Bianca Habermann, Linda Partridge, Chan Bae Park, Nils-Göran Larsson
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003178 (2013)
Regulation of mitochondrial DNA (mtDNA) expression is critical for the control of oxidative phosphorylation in response to physiological demand, and this regulation is often impaired in disease and aging. We have previously shown that mitochondrial t
Externí odkaz:
https://doaj.org/article/552ff24687c845449ceccce47f040473
Autor:
Ana Bratic, Anna Wredenberg, Sebastian Grönke, James B Stewart, Arnaud Mourier, Benedetta Ruzzenente, Christian Kukat, Rolf Wibom, Bianca Habermann, Linda Partridge, Nils-Göran Larsson
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002324 (2011)
The bicoid stability factor (BSF) of Drosophila melanogaster has been reported to be present in the cytoplasm, where it stabilizes the maternally contributed bicoid mRNA and binds mRNAs expressed from early zygotic genes. BSF may also have other role
Externí odkaz:
https://doaj.org/article/e11fce0f497a42daba5830fd457069a4
Autor:
Miriam Cipullo, Xinping Li, Sarah F Pearce, Nils-Göran Larsson, Ilian Atanassov, Eduardo Silva Ramos, Thomas Schöndorf, Joanna Rorbach, Jakob D. Busch, Dusanka Milenkovic, Ana Bratic
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1728-1738.e9 (2019)
Cell Rep
Cell Reports
Cell Rep
Cell Reports
Summary Mitochondria harbor specialized ribosomes (mitoribosomes) necessary for the synthesis of key membrane proteins of the oxidative phosphorylation (OXPHOS) machinery located in the mitochondrial inner membrane. To date, no animal model exists to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df4f7b3dc8d09ea9936972bc5cd89da
http://www.sciencedirect.com/science/article/pii/S2211124719312847
http://www.sciencedirect.com/science/article/pii/S2211124719312847
Autor:
Nils-Göran Larsson, Arnaud Mourier, Christoph Freyer, Ana Bratic, Roberta Filograna, Craig Stamp, Marie-Lune Simard, Johanna H.K. Kauppila, James B. Stewart, Holly L. Baines, Laura C. Greaves
Publikováno v:
Cell Reports
Cell Reports, Vol 16, Iss 11, Pp 2980-2990 (2016)
Cell Rep
Cell Reports, Vol 16, Iss 11, Pp 2980-2990 (2016)
Cell Rep
Summary Mutations of mtDNA are an important cause of human disease, but few animal models exist. Because mammalian mitochondria cannot be transfected, the development of mice with pathogenic mtDNA mutations has been challenging, and the main strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c824f6f9ee2b07b5edd40e78024257a
https://doi.org/10.1016/j.celrep.2016.08.037
https://doi.org/10.1016/j.celrep.2016.08.037
Autor:
Francesca Baggio, Sebastian Grönke, Linda Partridge, Nils-Göran Larsson, Ana Bratic, Timo E.S. Kauppila, Martin Borch Jensen, Heinrich Jasper
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Mutations of mtDNA accumulate in aging humans and other mammals to cause mitochondrial dysfunction in a subset of cells in various tissues. Furthermore, experimental induction of mtDNA mutations causes a premature aging syndrome in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa15771d730ee70714f4d4206b982ab
https://hdl.handle.net/21.11116/0000-000B-47CF-D
https://hdl.handle.net/21.11116/0000-000B-47CF-D
Autor:
Nils-Göran Larsson, Ana Bratic
Publikováno v:
J Clin Invest
Over the last decade, accumulating evidence has suggested a causative link between mitochondrial dysfunction and major phenotypes associated with aging. Somatic mitochondrial DNA (mtDNA) mutations and respiratory chain dysfunction accompany normal ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26f7b932839884129cb900cf0df7c1d
https://doi.org/10.1172/jci64125
https://doi.org/10.1172/jci64125