Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Ana Blas-Garcia"'
Autor:
Ana M. Benedicto, Federico Lucantoni, Isabel Fuster-Martínez, Pedro Diaz-Pozo, Dimitri Dorcaratto, Elena Muñoz-Forner, Victor M. Victor, Juan V. Esplugues, Ana Blas-García, Nadezda Apostolova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117206- (2024)
Activated hepatic stellate cells (aHSCs), the main perpetrators of liver fibrosis, are a promising therapeutic target in the treatment of chronic liver disease. During liver injury, HSCs transcend from a quiescent to a fibrotic phenotype, a process w
Externí odkaz:
https://doaj.org/article/4566746598384a248dc57308c0adc8a0
Autor:
Nadezda Apostolova, Juan V. Esplugues, Ana Blas-Garcia, Isabel Fuster-Martínez, Joan Tosca, Ana M Benedicto
Publikováno v:
Cells
Cells, Vol 10, Iss 1687, p 1687 (2021)
Cells, Vol 10, Iss 1687, p 1687 (2021)
Due to the improved effectiveness and safety of combined antiretroviral therapy, human immunodeficiency virus (HIV) infection has become a manageable, chronic condition rather than a mortal disease. However, HIV patients are at increased risk of expe
Autor:
Federico Lucantoni, Juan V. Esplugues, Andreu Martínez-Cerezuela, Ángela B. Moragrega, Victor M. Victor, Aleksandra Gruevska, Ana Blas-Garcia, Nadezda Apostolova
Publikováno v:
The Journal of pathologyReferences. 254(3)
Liver fibrosis (LF) occurs as a result of persistent liver injury and can be defined as a pathologic, chronic, wound-healing process in which functional parenchyma is progressively replaced by fibrotic tissue. As a phenomenon involved in the majority
Autor:
Andrea Cossarizza, Aleksandra Gruevska, J Esplugues, Ángela B. Moragrega, Nadezda Apostolova, Ana Blas-Garcia
Publikováno v:
Cells
Cells, Vol 10, Iss 410, p 410 (2021)
Cells, Vol 10, Iss 410, p 410 (2021)
Due to medical advances over the past few decades, human immunodeficiency virus (HIV) infection, once a devastatingly mortal pandemic, has become a manageable chronic condition. However, available antiretroviral treatments (cART) cannot fully restore
Autor:
Pablo Martí-Rodrigo, Francisco García-García, Nadezda Apostolova, Alberto Martí-Rodrigo, Fernando Alegre, Jordi Gracia-Sancho, J Esplugues, Ángela B. Moragrega, Anabel Fernández-Iglesias, Ana Blas-Garcia
Publikováno v:
GUT
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Gut
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Gut
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
ObjectiveLiver fibrosis constitutes a major health problem worldwide due to its rapidly increasing prevalence and the lack of specific and effective treatments. Growing evidence suggests that signalling through cytokine-activated Janus kinase (JAK)-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546e45db381e4642518af33d338fa33a
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3659
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=3659
Autor:
Ángela B. Moragrega, María José Galindo, Aleksandra Gruevska, Ana Blas-Garcia, Nadezda Apostolova, Juan V. Esplugues
Publikováno v:
Antiviral research. 178
The improved effectiveness and safety of the combined antiretroviral therapy (cART) has largely diminished mortality and AIDS-defining morbidity of HIV-patients. Nevertheless, chronic age-related diseases in these individuals are more common and thei
Autor:
J Esplugues, Nadezda Apostolova, Miriam Polo, Fernando Alegre, Ángela B. Moragrega, Ana Blas-Garcia, Alberto Martí-Rodrigo
Publikováno v:
British Journal of Pharmacology. 175:440-455
Background and Purpose SQSTM1/p62 is a multifunctional, stress-induced, scaffold protein involved in multiple cellular processes including autophagic clearance, regulation of inflammatory responses and redox homeostasis. Its altered function has been
Autor:
J Esplugues, Ana Blas-Garcia, Nadezda Apostolova, Alberto Martí-Rodrigo, Lara Gibellini, Miriam Polo, Fernando Alegre, Ángela B. Moragrega
Publikováno v:
British Journal of Pharmacology. 174:4409-4429
Background and Purpose Mitochondria-associated membranes (MAMs) are specific endoplasmic reticulum (ER) domains that enable it to interact directly with mitochondria and mediate metabolic flow and Ca2+ transfer. A growing list of proteins have been i
Publikováno v:
European Journal of Pharmacology. 812:163-173
The HIV infection remains an important health problem worldwide. However, due to the efficacy of combined antiretroviral therapy (cART), it has ceased to be a mortal condition, becoming a chronic disease instead. Efavirenz, the most prescribed non-nu
Autor:
Patricia Gandía, Isabel Andújar, Lara Milian, Ana Blas-Garcia, José Luis Górriz, José E. Peris, Luis M Pallardó
Publikováno v:
AIDS. 31:1679-1684
OBJECTIVE In-vivo studies suggest that mitochondria is involved in tenofovir (TFV)-induced renal toxicity, but the underlying mechanisms are still unclear. The aim of the present study was to assess the effects of TFV and its prodrug, TFV disoproxil