Cordyceps militaris (L.) Link Fruiting Body Reduces the Growth of a Non-Small Cell Lung Cancer Cell Line by Increasing Cellular Levels of p53 and p21

Autor: Ana Bizarro, Isabel C. F. R. Ferreira, Marina Soković, Leo J. L. D. van Griensven, Diana Sousa, M. Helena Vasconcelos, Raquel T. Lima

Publikováno v: Molecules, Vol 20, Iss 8, Pp 13927-13940 (2015)

Cordyceps militaris (L.) Link, an edible entomopathogenic fungus widely used in traditional Chinese medicine, has numerous potential medicinal properties including antitumor activity. The methanolic extract of C. militaris fruiting body was recently

Externí odkaz: https://doaj.org/article/95604a43f9544a9895ce7f2cea7d7f8c

Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors

Autor: Loana Musso, Raquel T. Lima, Raffaella Cincinelli, Ana Bizarro, Michelandrea De Cesare, Sabrina Dallavalle, M. Helena Vasconcelos, Valentina Zuco, Diana Sousa

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 2, p 407 (2018)
Molecules; Volume 23; Issue 2; Pages: 407
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Background: Heat shock protein 90 (HSP90) is a well-known target for cancer therapy. In a previous work, some of us have reported a series of 3-aryl-naphtho[2,3-d]isoxazole-4,9-diones as inhibitors of HSP90. Methods: In the present work, various comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638850e929e3ec4d77bf8fdf3caa98da
http://europepmc.org/articles/PMC6017909