Výsledky vyhledávání - "Ana Belén Carrillo-Gálvez"

Akademický článek

GARP is a key molecule for mesenchymal stromal cell responses to TGF‐β and fundamental to control mitochondrial ROS levels

Autor: Ana Belén Carrillo‐Gálvez, Sheyla Gálvez‐Peisl, Juan Elías González‐Correa, Marina deHaro‐Carrillo, Verónica Ayllón, Pedro Carmona‐Sáez, Verónica Ramos‐Mejía, Pablo Galindo‐Moreno, Francisca E. Cara, Sergio Granados‐Principal, Pilar Muñoz, Francisco Martin, Per Anderson

Publikováno v: Stem Cells Translational Medicine, Vol 9, Iss 5, Pp 636-650 (2020)

Abstract Multipotent mesenchymal stromal cells (MSCs) have emerged as a promising cell therapy in regenerative medicine and for autoimmune/inflammatory diseases. However, a main hurdle for MSCs‐based therapies is the loss of their proliferative pot

Externí odkaz: https://doaj.org/article/8ef05891c4e145d19d4652a49c245382

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Akademický článek

CD105 (endoglin)-negative murine mesenchymal stromal cells define a new multipotent subpopulation with distinct differentiation and immunomodulatory capacities.

Autor: Per Anderson, Ana Belén Carrillo-Gálvez, Angélica García-Pérez, Marién Cobo, Francisco Martín

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76979 (2013)

Administration of in vitro expanded mesenchymal stromal cells (MSCs) represents a promising therapy for regenerative medicine and autoimmunity. Both mouse and human MSCs ameliorate autoimmune disease in syn-, allo- and xenogeneic settings. However, M

Externí odkaz: https://doaj.org/article/36bd1d6b75d447c0b8f8ee66c88f145c

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GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-β

Autor: Juan Elías González-Correa, Per Anderson, Virgínea de Araújo Farias, Sofía T. Menéndez, M. Victoria Gonzalez, Juan Esteban Quintero, Sabina Sánchez-Hernández, Turid Hellevik, Juan Carlos Rodríguez-Manzaneque, Verónica Blanco-Lorenzo, Inigo Martinez-Zubiaurre, Federico Zurita, Eva Allonca, Nadina Erill-Sagalés, Rene Rodriguez, Francisco Martin, Pilar M. Muñoz, Ana Belén Carrillo-Gálvez

Publikováno v: Cell Death and Disease, Vol 11, Iss 11, Pp 1-12 (2020)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
WOS:000595630900001
RUO. Repositorio Institucional de la Universidad de Oviedo
Cell Death & Disease
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

Sarcomas are mesenchymal cancers with poor prognosis, representing about 20% of all solid malignancies in children, adolescents, and young adults. Radio- and chemoresistance are common features of sarcomas warranting the search for novel prognostic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee03eb08eddc721e193320026582b2f
https://doi.org/10.1038/s41419-020-03197-z

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GARP is a key molecule for mesenchymal stromal cell responses to TGF-β and fundamental to control mitochondrial ROS levels

Autor: Marina de Haro-Carrillo, Francisca E. Cara, Ana Belén Carrillo-Gálvez, Juan Elías González-Correa, Francisco Martin, Per Anderson, Verónica Ramos-Mejía, Sheyla Gálvez-Peisl, Sergio Granados-Principal, Verónica Ayllón, Pedro Carmona-Sáez, Pablo Galindo-Moreno, Pilar Muñoz

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 5, Pp 636-650 (2020)

Multipotent mesenchymal stromal cells (MSCs) have emerged as a promising cell therapy in regenerative medicine and for autoimmune/inflammatory diseases. However, a main hurdle for MSCs‐based therapies is the loss of their proliferative potential in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77feb4f8361f501e3a820a21eea07e3a
https://hdl.handle.net/10668/15129

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TGF-β and mesenchymal stromal cells in regenerative medicine, autoimmunity and cancer

Autor: Ana Belén Carrillo-Gálvez, Per Anderson, Francisco Martin, Virgínea de Araújo Farias

Publikováno v: Cytokinegrowth factor reviews. 43

Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in regenerative medicine and for the treatment of inflammatory/autoimmune diseases. Importantly, MSCs have emerged as an important contributor to the tumor stroma w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eff43d9db941b5222cb8792dfa9e10
https://pubmed.ncbi.nlm.nih.gov/29954665

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The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes

Autor: Per Anderson, Francisco Martin, Karim Benabdellah, Sabina Sánchez-Hernández, Laura Sánchez, Alejandra Gutierrez-Guerrero, Ana Belén Carrillo-Gálvez, Sandra Rodriguez-Perales, Jesús Chato-Astrain, Jose L. Garcia-Perez, Rocio Martin-Guerra, María Tristán-Manzano, Marina Cortijo-Gutiérrez, Pedro J. Real, Rosa Montes, Ricardo Fernández-Valadés

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Molecular Therapy: Nucleic Acids, Vol 13, Iss, Pp 16-28 (2018)

Integration-defective lentiviral vectors (IDLVs) have become an important alternative tool for gene therapy applications and basic research. Unfortunately, IDLVs show lower transgene expression as compared to their integrating counterparts. In this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b25c68ffdcd39fd0faae5ee8ca6f4ca
http://hdl.handle.net/20.500.12105/6743

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Mesenchymal Stromal Cells Express GARP/LRRC32 on Their Surface: Effects on Their Biology and Immunomodulatory Capacity

Autor: Ana Belén Carrillo-Gálvez, Almudena Sánchez-Gilabert, Marién Cobo, Per Anderson, Karim Benabdellah, Pilar Muñoz, Sara Cuevas‐Ocaña, Francisco Martin, Miguel G. Toscano, Alejandra Gutierrez-Guerrero, Angélica García-Pérez, Pierpaolo Bongarzone

Publikováno v: Stem Cells (Dayton, Ohio)

Mesenchymal stromal cells (MSCs) represent a promising tool for therapy in regenerative medicine, transplantation, and autoimmune disease due to their trophic and immunomodulatory activities. However, we are still far from understanding the mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a74461a19efb40b6addb917931bd83
http://europepmc.org/articles/PMC4309416

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Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells

Autor: Francisco Martin, Karim Benabdellah, Ana Belén Carrillo-Gálvez, Sabina Sánchez-Hernández, Per Anderson, Alejandra Gutierrez-Guerrero, Marién Cobo, Pilar Muñoz, Angélica García-Pérez, Miguel G. Toscano

Publikováno v: Scientific Reports

Conditional transgene expression in human stem cells has been difficult to achieve due to the low efficiency of existing delivery methods, the strong silencing of the transgenes and the toxicity of the regulators. Most of the existing technologies ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d7de027df135a0109651a55f0e5625
https://pubmed.ncbi.nlm.nih.gov/27853296

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Akademický článek

The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes

Autor: Sabina Sánchez-Hernández, Alejandra Gutierrez-Guerrero, Rocío Martín-Guerra, Marina Cortijo-Gutierrez, María Tristán-Manzano, Sandra Rodriguez-Perales, Laura Sanchez, Jose Luis Garcia-Perez, Jesus Chato-Astrain, Ricardo Fernandez-Valades, Ana Belén Carrillo-Galvez, Per Anderson, Rosa Montes, Pedro J. Real, Francisco Martin, Karim Benabdellah

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 16-28 (2018)

Externí odkaz: https://doaj.org/article/72961106e0f041648c1d03824c09a7c3

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