Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Ana Barabash"'
Early visual alterations in individuals at-risk of Alzheimer’s disease: a multidisciplinary approach
Autor:
Inés López-Cuenca, Alberto Nebreda, Alejandra García-Colomo, Elena Salobrar-García, Jaisalmer de Frutos-Lucas, Ricardo Bruña, Ana I. Ramírez, Federico Ramirez-Toraño, Juan J. Salazar, Ana Barabash, Pedro Gil, Fernando Maestú, José M. Ramírez, Rosa de Hoz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background The earliest pathological features of Alzheimer’s disease (AD) appear decades before the clinical symptoms. The pathology affects the brain and the eye, leading to retinal structural changes and functional visual alterations. He
Externí odkaz:
https://doaj.org/article/bc475c7058714ca2b14c0387f293f041
Autor:
Inés López-Cuenca, Alberto Marcos-Dolado, Miguel Yus-Fuertes, Elena Salobrar-García, Lorena Elvira-Hurtado, José A. Fernández-Albarral, Juan J. Salazar, Ana I. Ramírez, Lidia Sánchez-Puebla, Manuel Enrique Fuentes-Ferrer, Ana Barabash, Federico Ramírez-Toraño, Lidia Gil-Martínez, Juan Arrazola-García, Pedro Gil, Rosa de Hoz, José M. Ramírez
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Two main genetic risks for sporadic Alzheimer’s disease (AD) are a family history and ɛ4 allele of apolipoprotein E. The brain and retina are part of the central nervous system and share pathophysiological mechanisms in AD. Met
Externí odkaz:
https://doaj.org/article/49329f36ef8c4e2d84f49e46a209ad7b
Autor:
Ana Ramos-Levi, Ana Barabash, Johanna Valerio, Nuria García de la Torre, Leire Mendizabal, Mirella Zulueta, Maria Paz de Miguel, Angel Diaz, Alejandra Duran, Cristina Familiar, Inés Jimenez, Laura del Valle, Veronica Melero, Inmaculada Moraga, Miguel A. Herraiz, María José Torrejon, Maddi Arregi, Laureano Simón, Miguel A. Rubio, Alfonso L. Calle-Pascual
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
HypothesisGestational diabetes mellitus (GDM) entails a complex underlying pathogenesis, with a specific genetic background and the effect of environmental factors. This study examines the link between a set of single nucleotide polymorphisms (SNPs)
Externí odkaz:
https://doaj.org/article/0cd90110c5af46d1bc97bae7cc946c78
Autor:
Inés López-Cuenca, Lidia Sánchez-Puebla, Elena Salobrar-García, María Álvarez-Gutierrez, Lorena Elvira-Hurtado, Ana Barabash, Federico Ramírez-Toraño, José A. Fernández-Albarral, José A. Matamoros, Alberto Nebreda, Alejandra García-Colomo, Ana I. Ramírez, Juan J. Salazar, Pedro Gil, Fernando Maestú, José M. Ramírez, Rosa de Hoz
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2024 (2023)
This study aimed to analyze the evolution of visual changes in cognitively healthy individuals at risk for Alzheimer’s disease (AD). Participants with a first-degree family history of AD (FH+) and carrying the Ε4+ allele for the ApoE gene (ApoE ε
Externí odkaz:
https://doaj.org/article/ea301ad1b5a94688aecbd2ea5a9bb57a
Autor:
Jaisalmer de Frutos-Lucas, Pablo Cuesta, Federico Ramírez-Toraño, Alberto Nebreda, Esther Cuadrado-Soto, África Peral-Suárez, David Lopez-Sanz, Ricardo Bruña, Silvia Marcos-de Pedro, María Luisa Delgado-Losada, Ana María López-Sobaler, Inmaculada Concepción Rodríguez-Rojo, Ana Barabash, Juan Manuel Serrano Rodriguez, Simon M. Laws, Alberto Marcos Dolado, Ramón López-Higes, Belinda M. Brown, Fernando Maestú
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Electrophysiological studies show that reductions in power within the alpha band are associated with the Alzheimer’s disease (AD) continuum. Physical activity (PA) is a protective factor that has proved to reduce AD risk and pat
Externí odkaz:
https://doaj.org/article/e58053f2a18b45e996064fdbab0daef6
Autor:
Jaisalmer de Frutos-Lucas, Pablo Cuesta, David López-Sanz, África Peral-Suárez, Esther Cuadrado-Soto, Federico Ramírez-Toraño, Belinda M. Brown, Juan M. Serrano, Simon M. Laws, Inmaculada C. Rodríguez-Rojo, Juan Verdejo-Román, Ricardo Bruña, Maria L. Delgado-Losada, Ana Barabash, Ana M. López-Sobaler, Ramón López-Higes, Alberto Marcos, Fernando Maestú
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Neuronal hyperexcitability and hypersynchrony have been described as key features of neurophysiological dysfunctions in the Alzheimer’s disease (AD) continuum. Conversely, physical activity (PA) has been associated with improved
Externí odkaz:
https://doaj.org/article/bf6af75c91304682a9614a62083b0a10
Autor:
Isabelle Runkle, María Paz de Miguel, Ana Barabash, Martin Cuesta, Ángel Diaz, Alejandra Duran, Cristina Familiar, Nuria García de la Torre, Miguel Ángel Herraiz, Nuria Izquierdo, Clara Marcuello, Pilar Matia, Verónica Melero, Carmen Montañez, Inmaculada Moraga, Natalia Perez-Ferre, Noelia Perez, Carla Assaf-Balut, Miguel Ángel Rubio, Jorge Gabriel Ruiz-Sanchez, Concepción Sanabria, María José Torrejon, Johanna Valerio, Laura del Valle, Alfonso Calle-Pascual
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The optimal maternal levels of thyroid hormones (TH) during the first trimester of gestation have not been established, nor has the ideal moment to initiate levothyroxine treatment (LT) to improve the evolution of gestation and fetal development. Cut
Externí odkaz:
https://doaj.org/article/dfbf3e98860842b38ea97358f183f232
Autor:
Ana Barabash, Johanna D. Valerio, Nuria Garcia de la Torre, Inés Jimenez, Laura del Valle, Verónica Melero, Carla Assaf-Balut, Manuel Fuentes, Elena Bordiu, Alejandra Durán, Miguel A. Herraiz, Nuria Izquierdo, María J. Torrejón, Paz de Miguel, Isabelle Runkle, Miguel A. Rubio, Alfonso L. Calle-Pascual
Publikováno v:
Metabolism Open, Vol 8, Iss , Pp 100069- (2020)
Objective: There is sparse evidence for the impact of gene-diet interaction on gestational diabetes mellitus (GDM) onset. Recent findings have shown that late first-trimester high adherence to a Mediterranean diet (MedDiet) pattern is associated with
Externí odkaz:
https://doaj.org/article/0ac22cd44dec4c43b16007f63d2c791c
Autor:
Inés López-Cuenca, Rosa de Hoz, Celia Alcántara-Rey, Elena Salobrar-García, Lorena Elvira-Hurtado, José A. Fernández-Albarral, Ana Barabash, Federico Ramírez-Toraño, Jaisalmer de Frutos-Lucas, Juan J. Salazar, Ana I. Ramírez, José M. Ramírez
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 638 (2021)
A family history (FH+) of Alzheimer’s disease (AD) and ɛ4 allele of the ApoE gene are the main genetic risk factors for developing AD, whereas ɛ4 allele plays a protective role in age-related macular degeneration. Ocular vascular changes have bee
Externí odkaz:
https://doaj.org/article/9becff96601d4c6ab645bec83eea1aef
Autor:
Inmaculada C. Rodríguez-Rojo, Pablo Cuesta, María Eugenia López, Jaisalmer de Frutos-Lucas, Ricardo Bruña, Ernesto Pereda, Ana Barabash, Pedro Montejo, Mercedes Montenegro-Peña, Alberto Marcos, Ramón López-Higes, Alberto Fernández, Fernando Maestú
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The pathophysiological processes undermining brain functioning decades before the onset of the clinical symptoms associated with dementia are still not well understood. Several heritability studies have reported that the Brain Derived Neurotrophic Fa
Externí odkaz:
https://doaj.org/article/b6dc7b936d654c0284be5ad1d4a646bb