Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Ana B. Chepelinsky"'
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Lens Major Intrinsic Protein (MIP)/Aquaporin 0 Expression in Rat Lens Epithelia Explants Requires Fibroblast Growth Factor-induced ERK and JNK Signaling
Autor: Jianguo Fan, Ana B. Chepelinsky, Peggy S. Zelenka, Robert N. Fariss, Nady Golestaneh, Woo Kuen Lo
Publikováno v: Journal of Biological Chemistry. 279:31813-31822
Lens major intrinsic protein (MIP), exclusive to the vertebrate lens, otherwise known as MIP26 and Aquaporin 0, is abundantly expressed as a lens fiber membrane protein. Although relatively less efficient compared with other aquaporins, MIP is sugges
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ba421fa05fc013f5023036a5516ed0
https://doi.org/10.1074/jbc.m403473200
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4
A 76-bp deletion in the Mip gene causes autosomal dominant cataract in Hfi mice
Autor: Angelika Neuhäuser-Klaus, Chiaki Ohtaka-Maruyama, Patricia A. Grimes, William R. Skach, Walter Pretsch, Dwight Stambolian, Yun Lu, Ana B. Chepelinsky, Peter M.T. Deen, Alvina Bragin, Jack Favor, D.J. Sidjanin, Devonne M. Parker-Wilson
Publikováno v: Genomics : International Journal of Gene Mapping and Nucleotide Sequencing Emphasizing Analyses of the Human and Other Complex Genomes, 74, 313--9
Genomics : International Journal of Gene Mapping and Nucleotide Sequencing Emphasizing Analyses of the Human and Other Complex Genomes, 74, 3, pp. 313--9
Item does not contain fulltext Hfi is a dominant cataract mutation where heterozygotes show hydropic lens fibers and homozygotes show total lens opacity. The Hfi locus was mapped to the distal part of mouse chromosome 10 close to the major intrinsic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fcf0f03ac203c4d8371abd3afbd946
https://doi.org/10.1006/geno.2001.6509
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5
Expression of Interferon-γ in the Lens Exacerbates Anterior Uveitis and Induces Retinal Degenerative Changes in Transgenic Lewis Rats
Autor: Janine A. Smith, Ana B. Chepelinsky, Chi-Chao Chan, Charles E. Egwuagu, Wenmei Li, Rashid M. Mahdi, Jorge Sztein
Publikováno v: Clinical Immunology. 91:196-205
Interferon-gamma (IFN-gamma) is a pleiotropic cytokine that has been implicated in immunopathogenic mechanisms of a number of inflammatory diseases of autoimmune or infectious disease etiology. However, its exact role is still a matter of debate. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0196462bf39be506bc656cf9a80e3f98
https://doi.org/10.1006/clim.1999.4701
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6
Interferon Consensus Sequence-binding Protein Is Constitutively Expressed and Differentially Regulated in the Ocular Lens
Autor: Chandrasekharam N. Nagineni, Ana B. Chepelinsky, Bassey J.S. Efiok, Wenmei Li, Hong Ge, Charles E. Egwuagu
Publikováno v: Journal of Biological Chemistry. 274:9686-9691
Interferon signaling is mediated by STATs and interferon regulatory factor (IRF) families of transcription factors. Ten distinct IRFs have been described and most are expressed in a variety of cells except for interferon consensus sequence-binding pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5abc0b5381aba964977b5184473499
https://doi.org/10.1074/jbc.274.14.9686
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7
IFN-γ Increases the Severity and Accelerates the Onset of Experimental Autoimmune Uveitis in Transgenic Rats
Autor: Charles E. Egwuagu, Jorge Sztein, Rashid M. Mahdi, Wenmei Li, Chi Chao-Chan, Janine A. Smith, Puwat Charukamnoetkanok, Ana B. Chepelinsky
Publikováno v: The Journal of Immunology. 162:510-517
Experimental autoimmune uveitis (EAU) is a predominantly Th1-mediated intraocular inflammatory disease that serves as a model for studying the immunopathogenic mechanisms of uveitis and organ-specific autoimmune diseases. Despite the well-documented
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a867790dee95c3c9388703a96c61a8e
https://doi.org/10.4049/jimmunol.162.1.510
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8
A Novel Alternative Spliced Variant of the Transcription Factor AP2α Is Expressed in the Murine Ocular Lens
Autor: Chiaki Ohtaka-Maruyama, Ana B. Chepelinsky, Fumio Hanaoka
Publikováno v: Developmental Biology. 202(1):125-135
The AP2alpha gene encodes a transcription factor containing a basic, helix-span-helix DNA-binding/dimerization domain, which is developmentally regulated and retinoic acid inducible. Recent reports about AP2alpha null mice indicate that AP2alpha play
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a85e735a833417520921f7d4a903592
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9
Overlapping Sp1 and AP2 binding sites in a promoter element of the lens-specific MIP gene
Autor: Chiaki Ohtaka-Maruyama, Hong Ge, Ana B. Chepelinsky, Xiao Yan Wang
Publikováno v: Nucleic Acids Research. 26:407-414
The MIP gene, the founder of the MIP family of channel proteins, is specifically expressed in fiber cells of the ocular lens and expression is regulated temporally and spatially during development. We previously found that a DNA fragment containing 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf3e0840246ea1a4c4434d55db71cd9
https://doi.org/10.1093/nar/26.2.407
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