Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ana Nóvoa"'
Autor:
Rion Brattig-Correia, Joana M Almeida, Margot Julia Wyrwoll, Irene Julca, Daniel Sobral, Chandra Shekhar Misra, Sara Di Persio, Leonardo Gastón Guilgur, Hans-Christian Schuppe, Neide Silva, Pedro Prudêncio, Ana Nóvoa, Ana S Leocádio, Joana Bom, Sandra Laurentino, Moises Mallo, Sabine Kliesch, Marek Mutwil, Luis M Rocha, Frank Tüttelmann, Jörg D Becker, Paulo Navarro-Costa
Publikováno v:
eLife, Vol 13 (2024)
Male germ cells share a common origin across animal species, therefore they likely retain a conserved genetic program that defines their cellular identity. However, the unique evolutionary dynamics of male germ cells coupled with their widespread lea
Externí odkaz:
https://doaj.org/article/2abf73b38c2f4697a2904a171653c40a
Autor:
Liliana Oliveira, M. Carolina Silva, Ana P. Gomes, Rita F. Santos, Marcos S. Cardoso, Ana Nóvoa, Hervé Luche, Bruno Cavadas, Irina Amorim, Fátima Gärtner, Bernard Malissen, Moisés Mallo, Alexandre M. Carmo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sepsis results from systemic, dysregulated inflammatory responses to infection, culminating in multiple organ failure. Here, we demonstrate the utility of CD5L for treating experimental sepsis caused by cecal ligation and puncture (CLP). We
Externí odkaz:
https://doaj.org/article/b069eaf5d01f4fed8e7e71994fabe4ac
Autor:
Anastasiia Lozovska, Artemis G. Korovesi, André Dias, Alexandre Lopes, Donald A. Fowler, Gabriel G. Martins, Ana Nóvoa, Moisés Mallo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The hindlimb and external genitalia of present-day tetrapods are thought to derive from an ancestral common primordium that evolved to generate a wide diversity of structures adapted for efficient locomotion and mating in the ecological nich
Externí odkaz:
https://doaj.org/article/6d4bb31d50b74e95a1a9a8674316316b
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Development of vertebrate embryos is characterized by early formation of the anterior tissues followed by the sequential extension of the axis at their posterior end to build the trunk and tail structures, first by the activity of
Externí odkaz:
https://doaj.org/article/71a5ff7db0ac40d491ec27ebe651536b
Autor:
Thomas Spruce, Mireya Plass, André Gohr, Debashish Ray, María Martínez de Lagrán, Gregor Rot, Ana Nóvoa, Demian Burguera, Jon Permanyer, Marta Miret, Hong Zheng, Maurice S Swanson, Quaid Morris, Moises Mallo, Mara Dierssen, Timothy R Hughes, Barbara Pernaute, Manuel Irimia
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001615 (2022)
Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process of evolutionary specializati
Externí odkaz:
https://doaj.org/article/123842fa9e434a1097df0caff61e1e6d
Autor:
André Dias, Anastasiia Lozovska, Filip J Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral, Gabriel G Martins, Valerie Wilson, Moises Mallo
Publikováno v:
eLife, Vol 9 (2020)
Formation of the vertebrate postcranial body axis follows two sequential but distinct phases. The first phase generates pre-sacral structures (the so-called primary body) through the activity of the primitive streak on axial progenitors within the ep
Externí odkaz:
https://doaj.org/article/2737e4e803004f67abc130ae14520e08
Development of vertebrate embryos is characterized by early formation of the anterior tissues followed by the sequential extension of the axis at their posterior end to build the trunk and tail structures, first by the activity of the primitive strea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb23f49c229ef9d51c0c4fa7b41c5eb
https://doi.org/10.1101/2022.12.18.520961
https://doi.org/10.1101/2022.12.18.520961
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 251(10)
The turtle carapace is an evolutionary novelty resulting from changes in the processes that build ribs and their associated muscles in most tetrapod species. Turtle embryos have several unique features that might play a role in this process, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf251ba8a61cc962d2644bae8f78446
https://pubmed.ncbi.nlm.nih.gov/35618666
https://pubmed.ncbi.nlm.nih.gov/35618666
Autor:
Rita F. Santos, Annika De Sousa Linhares, Marcos S. Cardoso, Ana Nóvoa, Hervé Luche, Fátima Gärtner, Bernard Malissen, Peter Steinberger, Simon. J. Davis, Moisés Mallo, Liliana Oliveira, Alexandre M. Carmo
T-cell membrane scaffold proteins play important roles in T cell biology, functioning as multi-functional signaling hubs. CD6 assembles a large intracellular signalosome but, unlike typical membrane-attached scaffolds like LAT or PAG, it has a sizeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8e52444fee8c6e0d85943771c8163b
https://doi.org/10.1101/2022.04.29.490054
https://doi.org/10.1101/2022.04.29.490054
Publikováno v:
Development. 149
The vertebrate body is built during embryonic development by the sequential addition of new tissue as the embryo grows at its caudal end. During this process, progenitor cells within the neuromesodermal competent (NMC) region generate the postcranial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df4503626646de830c6b6aa1d00a7f0
https://doi.org/10.1242/dev.198812
https://doi.org/10.1242/dev.198812