Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ana Águeda-Pinto"'
Publikováno v:
Viruses, Vol 16, Iss 8, p 1272 (2024)
Viruses are obligate intracellular pathogens as their replication depends on the metabolism of the host cell. The induction of cellular suicide, known as programmed cell death (PCD), has the potential to hinder viral replication and act as a first li
Externí odkaz:
https://doaj.org/article/25fa9561d3254f328108306d39ec421e
Autor:
Ana Águeda-Pinto, Simona Kraberger, Anne Everts, Ami Gutierrez-Jensen, Honor L. Glenn, Kevin P. Dalton, Ana Podadera, Francisco Parra, Monica Martinez-Haro, José Alberto Viñuelas, Arvind Varsani, Grant McFadden, Masmudur M. Rahman, Pedro J. Esteves
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Myxoma virus (MYXV) is naturally found in rabbit Sylvilagus species and is known to cause lethal myxomatosis in European rabbits (Oryctolagus cuniculus). In 2019, an MYXV strain (MYXV strain Toledo [MYXV-Tol]) causing myxomatosis-like diseas
Externí odkaz:
https://doaj.org/article/87034227d5ba4791a6a2dd9b2a7b0047
Autor:
Ana Pinheiro, Ana Águeda-Pinto, José Melo-Ferreira, Fabiana Neves, Joana Abrantes, Pedro J. Esteves
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Toll-like receptors (TLRs) are the most widely studied innate immunity receptors responsible for recognition of invading pathogens. Among the TLR family, TLR5 is the only that senses and recognizes flagellin, the major protein of
Externí odkaz:
https://doaj.org/article/85c7e1a5d06749498e13f36958a7697a
Autor:
Ana Águeda-Pinto, Luís Q. Alves, Fabiana Neves, Grant McFadden, Bertram L. Jacobs, L. Filipe C. Castro, Masmudur M. Rahman, Pedro J. Esteves
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Programmed cell death is a vital process in the life cycle of organisms. Necroptosis, an evolutionary form of programmed necrosis, contributes to the innate immune response by killing pathogen-infected cells. This virus-host interaction pathway is or
Externí odkaz:
https://doaj.org/article/8c01b8504b1f4abaa2f2da8e4970b4de
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The S100A7 gene, also called psoriasin, was first described as an upregulated protein in psoriatic skin. For the past years, the importance of this protein as a key effector of innate immunity has been clearly established, not onl
Externí odkaz:
https://doaj.org/article/1b774a72cd504c3c9e0dd84483173bee
Publikováno v:
Viruses, Vol 14, Iss 2, p 345 (2022)
The innate immunological response in mammals involves a diverse and complex network of many proteins. Over the last years, the tripartite motif-containing protein 5 (TRIM5) and 22 (TRIM22) have shown promise as restriction factors of a plethora of vi
Externí odkaz:
https://doaj.org/article/5d57f3d91dc343ee9f0aeb7633502a6d
Publikováno v:
Viruses, Vol 14, Iss 2, p 169 (2022)
Chemokine receptors are an important determinant for the infectiousness of different pathogens, which are able to target the host cells by binding to the extracellular domains of these proteins. This is the mechanism of infection of HIV-1, among othe
Externí odkaz:
https://doaj.org/article/c7b6260be8b54a53866c155101fce62c
Autor:
Ana Águeda-Pinto, Ana Lemos de Matos, Ana Pinheiro, Fabiana Neves, Patrícia de Sousa-Pereira, Pedro J Esteves
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226202 (2019)
The plethora of restriction factors with the ability to inhibit the replication of retroviruses have been widely studied and genetic hallmarks of evolutionary selective pressures in Primates have been well documented. One example is the tripartite mo
Externí odkaz:
https://doaj.org/article/12a92e05b70a480b95244105e914eb19
Autor:
Ana Águeda-Pinto, Simona Kraberger, Michael C. Lund, Christian Gortázar, Grant McFadden, Arvind Varsani, Pedro J. Esteves
Publikováno v:
Viruses, Vol 12, Iss 3, p 340 (2020)
Viruses are ubiquitous in nature; however, very few have been identified in the Leporid species. In the fall of 2018, an outbreak of myxomatosis in Iberian hares (Lepus granatensis) was reported in Spain and a novel recombinant myxoma virus strain (M
Externí odkaz:
https://doaj.org/article/88a4b820cd0b4bcdbb8bdc5a4b39f74c
Autor:
Ana Águeda-Pinto, Ana Lemos de Matos, Mário Abrantes, Simona Kraberger, Maria A. Risalde, Christian Gortázar, Grant McFadden, Arvind Varsani, Pedro J. Esteves
Publikováno v:
Viruses, Vol 11, Iss 6, p 530 (2019)
Myxomatosis is a lethal disease in wild European and domestic rabbits (Oryctolagus cuniculus), which is caused by a Myxoma virus (MYXV) infection—a leporipoxvirus that is found naturally in some Sylvilagus rabbit species in South America and Califo
Externí odkaz:
https://doaj.org/article/2eb249ae960c495b92995a6dd97771d6