Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.

Autor: Marine Blanc, Clara Lettl, Jérémy Guérin, Anaïs Vieille, Sven Furler, Sylvie Briand-Schumacher, Birgit Dreier, Célia Bergé, Andreas Plückthun, Sandrine Vadon-Le Goff, Rémi Fronzes, Patricia Rousselle, Wolfgang Fischer, Laurent Terradot

Publikováno v: PLoS Pathogens, Vol 19, Iss 5, p e1011368 (2023)

The bacterial human pathogen Helicobacter pylori produces a type IV secretion system (cagT4SS) to inject the oncoprotein CagA into gastric cells. The cagT4SS external pilus mediates attachment of the apparatus to the target cell and the delivery of C

Externí odkaz: https://doaj.org/article/7044c6721af0495787ccdbe2bca8e138

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.

Autor: Blanc, Marine¹ (AUTHOR), Lettl, Clara² (AUTHOR), Guérin, Jérémy¹ (AUTHOR), Vieille, Anaïs¹ (AUTHOR), Furler, Sven³ (AUTHOR), Briand-Schumacher, Sylvie³ (AUTHOR), Dreier, Birgit³ (AUTHOR), Bergé, Célia¹ (AUTHOR), Plückthun, Andreas³ (AUTHOR), Vadon-Le Goff, Sandrine⁴ (AUTHOR), Fronzes, Rémi⁵ (AUTHOR), Rousselle, Patricia⁴ (AUTHOR), Fischer, Wolfgang² (AUTHOR) Fischer@mvp.lmu.de, Terradot, Laurent¹ (AUTHOR) Fischer@mvp.lmu.de

Publikováno v: PLoS Pathogens. 5/8/2023, Vol. 18 Issue 5, p1-26. 26p.

Vindictus : Thriller

Autor: Patricia Vidal Schneider

Retrait du titre par le distributeur numérique, à la demande de l'éditeur.